Publications 2018

643 publications

Cryo-EM structure of the yeast respiratory supercomplex
Rathore S, Berndtsson J, Marin-Buera L, ..., Brzezinski P, Ott M
Nat Struct Mol Biol - (-) - [2018-12-31; online 2018-12-31]
Cryo-EM [Collaborative]
B cell alterations during BAFF inhibition with belimumab in SLE.
Ramsköld D, Parodis I, Lakshmikanth T, ..., Gunnarsson I, Malmström V
EBioMedicine - (-) - [2018-12-25; online 2018-12-25]
Cellular Immunomonitoring [Service]
Deep Learning in Image Cytometry: A Review
Gupta A, Harrison PJ, Wieslander H, ..., Sintorn IM, Wählby C
Cytometry - (-) - [2018-12-19; online 2018-12-19]
BioImage Informatics [Collaborative]
Carbon’s Three-Center, Four-Electron Tetrel Bond, Treated Experimentally
Karim A, Schulz N, Andersson H, ..., Keller S, Erdélyi M
J. Am. Chem. Soc. - (-) - [2018-12-07; online 2018-12-07]
Swedish NMR Centre (SNC) [Service]
Cotranslational Folding of a Pentarepeat β-Helix Protein.
Notari L, Martínez-Carranza M, Farías-Rico JA, Stenmark P, von Heijne G
J. Mol. Biol. 430 (24) 5196-5206 [2018-12-07; online 2018-10-27]
Protein Science Facility (PSF) [Service]
Porous Cellulose Nanofiber-Based Microcapsules for Biomolecular Sensing
Paulraj T, Wennmalm S, Riazanova AV, ..., Crespo GA, Svagan AJ
ACS Appl. Mater. Interfaces 10 (48) 41146-41154 [2018-12-05; online 2018-11-09]
Integrated Microscopy Technologies Stockholm [Collaborative]
Crystal Structures and Cytotoxicity of ent-Kaurane-Type Diterpenoids from Two Aspilia Species
Yaouba S, Valkonen A, Coghi P, ..., Erdélyi M, Yenesew A
Molecules 23 (12) 3199 [2018-12-04; online 2018-12-04]
Swedish NMR Centre (SNC) [Service]
Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins
Spåhr H, Chia T, Lingford JP, ..., Filipovska A, Rackham O
Nat Commun 9 (1) - [2018-12-00; online 2018-06-07]
Protein Science Facility (PSF) [Service]
Structure of a functional obligate complex III2IV2 respiratory supercomplex from Mycobacterium smegmatis
Wiseman B, Nitharwal RG, Fedotovskaya O, ..., Brzezinski P, Högbom M
Nat Struct Mol Biol 25 (12) 1128-1136 [2018-12-00; online 2018-12-05]
Cryo-EM [Service]
New tools for automated high-resolution cryo-EM structure determination in RELION-3
Zivanov J, Nakane T, Forsberg BO, ..., Lindahl E, Scheres SH
Elife 7 (-) - [2018-11-09; online 2018-11-09]
Cryo-EM [Technology development]
Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens
Srinivas V, Lebrette H, Lundin D, ..., Sjöberg BM, Högbom M
Nature 563 (7731) 416-420 [2018-11-00; online 2018-10-31]
Global Proteomics and Proteogenomics [Collaborative]
Glycomics@ExPASy: Bridging the Gap.
Mariethoz J, Alocci D, Gastaldello A, ..., Packer NH, Lisacek F
Mol. Cell Proteomics 17 (11) 2164-2176 [2018-11-00; online 2018-08-10]
Glycoproteomics [Collaborative]
Uncovering the regional localization of inhaled salmeterol retention in the lung.
Bäckström E, Hamm G, Nilsson A, ..., Goodwin RJA, Fridén M
Drug Deliv 25 (1) 838-845 [2018-11-00; online 2018-03-29]
Spatial Mass Spectrometry [Service]
XLSY: Extra-Large NMR Spectroscopy
Pustovalova Y, Mayzel M, Orekhov VY
Angew. Chem. Int. Ed. 57 (43) 14043-14045 [2018-10-22; online 2018-10-01]
Swedish NMR Centre (SNC) [Technology development]
Halogen Bond Asymmetry in Solution
Lindblad S, Mehmeti K, Veiga AX, ..., Gräfenstein J, Erdélyi M
J. Am. Chem. Soc. 140 (41) 13503-13513 [2018-10-17; online 2018-09-20]
Swedish NMR Centre (SNC) [Service]
BabA-mediated adherence of pediatric ulcerogenic H. pylori strains to gastric mucins at neutral and acidic pH.
Quintana-Hayashi MP, Rocha R, Padra M, ..., Oleastro M, Lindén SK
Virulence 9 (1) 1699-1717 [2018-10-10; online 2018-10-10]
Glycoproteomics [Service]
MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP
Jemth AS, Gustafsson R, Bräutigam L, ..., Stenmark P, Helleday T
Nucleic Acids Res - (-) - [2018-10-10; online 2018-10-10]
Protein Science Facility (PSF) [Service]
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Evangelou E, Warren HR, Mosen-Ansorena D, ..., Caulfield MJ, Million Veteran Program
Nat. Genet. 50 (10) 1412-1425 [2018-10-00; online 2018-09-17]
Bioinformatics Compute and Storage [Service]
Using Scipion for stream image processing at Cryo-EM facilities
Gómez-Blanco J, de la Rosa-Trevín JM, Marabini R, ..., Conesa P, Carazo JM
Journal of Structural Biology - (-) - [2018-10-00; online 2018-10-00]
Cryo-EM [Technology development]
Associations of Circulating Protein Levels With Lipid Fractions in the General Population
Figarska SM, Gustafsson S, Sundström J, ..., Lind L, Ingelsson E
Arterioscler Thromb Vasc Biol 38 (10) 2505-2518 [2018-10-00; online 2018-10-00]
Clinical Biomarkers [Service]
Plasma levels of the proprotein convertase furin and incidence of diabetes and mortality
Fernandez C, Rysä J, Almgren P, ..., Ruskoaho H, Melander O
J Intern Med 284 (4) 377-387 [2018-10-00; online 2018-07-02]
Clinical Biomarkers [Service]
The Xerobranching Response Represses Lateral Root Formation When Roots Are Not in Contact with Water
Orman-Ligeza B, Morris EC, Parizot B, ..., Beeckman T, Draye X
Current Biology 28 (19) 3165-3173.e5 [2018-10-00; online 2018-10-00]
Swedish Metabolomics Centre (SMC) [Service]
NMR Determination of the Binding Constant of Ionic Species: A Caveat
Schulz N, Schindler S, Huber SM, Erdelyi M
J. Org. Chem. 83 (18) 10881-10886 [2018-09-21; online 2018-08-15]
Swedish NMR Centre (SNC) [Service]
System-wide Identification and prioritization of Enzyme Substrates by Thermal Analysis (SIESTA)
Saei AA, Beusch C, Sabatier P, ..., Schuler H, Zubarev R
- - (-) - [2018-09-21; online 2018-09-21]
Chemical Proteomics [Collaborative]
ProTargetMiner: A proteome signature library of anticancer molecules for functional discovery
Saei AA, Chernobrovkin A, Sabatier P, ..., Vegvari A, Zubarev R
- - (-) - [2018-09-18; online 2018-09-18]
Chemical Proteomics [Technology development]
Neuroblastoma with flat genomic profile: a question of representativity?
Valind A, Öra I, Mertens F, Gisselsson D
BMJ Case Reports - (-) bcr-2018-225568 [2018-09-08; online 2018-09-08]
Clinical Genomics Lund [Service]
FADD (Fas-Associated Protein With Death Domain), Caspase-3, and Caspase-8 and Incidence of Ischemic Stroke
Muhammad IF, Borné Y, Melander O, ..., Söderholm M, Engström G
Stroke 49 (9) 2224-2226 [2018-09-00; online 2018-09-00]
Clinical Biomarkers [Service]
Ein Fall von Pankreaskarzinom
Löhr JM, Kordes M, Gustafsson-Liljefors M, ..., Permert J, Jäger D
Forum 33 (4) 232-235 [2018-09-00; online 2018-08-14]
Clinical Genomics Stockholm [Collaborative]
Broad spectrum developmental role of Brachypodium AUX1
van der Schuren A, Voiniciuc C, Bragg J, ..., Pauly M, Hardtke CS
New Phytol 219 (4) 1216-1223 [2018-09-00; online 2018-06-27]
Swedish Metabolomics Centre (SMC) [Service]
STK25 regulates oxidative capacity and metabolic efficiency in adipose tissue
Sütt S, Cansby E, Paul A, ..., Enerbäck S, Mahlapuu M
- 238 (3) 187-202 [2018-09-00; online 2018-09-00]
Integrated Microscopy Technologies Gothenburg [Service]
Diversity of Interneurons in the Dorsal Striatum Revealed by Single-Cell RNA Sequencing and PatchSeq.
Muñoz-Manchado AB, Bengtsson Gonzales C, Zeisel A, ..., Linnarsson S, Hjerling-Leffler J
Cell Rep 24 (8) 2179-2190.e7 [2018-08-21; online 2018-08-23]
Eukaryotic Single Cell Genomics (ESCG) [Service]
Pharmacokinetic Properties of the Nephrotoxin Orellanine in Rats.
Najar D, Haraldsson B, Thorsell A, ..., Nyström J, Ebefors K
Toxins (Basel) 10 (8) - [2018-08-17; online 2018-08-17]
Glycoproteomics [Service]
Proteomic Biomarkers for Incident Aortic Stenosis Requiring Valvular Replacement
Ljungberg J, Janiec M, Bergdahl IA, ..., Fall T, Söderberg S
Circulation 138 (6) 590-599 [2018-08-07; online 2018-08-07]
Clinical Biomarkers [Service]
A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function.
Jerlström Hultqvist J, Warsi O, Söderholm A, ..., Selmer M, Andersson DI
Nat Ecol Evol 2 (8) 1321-1330 [2018-08-00; online 2018-05-28]
Glycoproteomics [Collaborative]
Autoantibody profiling in intraocular fluid of patients with uveitis.
Ten Berge JC, Schreurs MW, van Rosmalen J, Rothova A
Exp. Eye Res. 176 (-) 141-146 [2018-07-10; online 2018-07-10]
Autoimmunity and Serology Profiling [Service]
Metabolic Profiling of Multiorgan Samples: Evaluation of MODY5/RCAD Mutant Mice
Torell F, Bennett K, Cereghini S, ..., Trygg J, Lundstedt T
J. Proteome Res. 17 (7) 2293-2306 [2018-07-06; online 2018-06-06]
Swedish Metabolomics Centre (SMC) [Service]
appreci8: a pipeline for precise variant calling integrating 8 tools
Sandmann S, Karimi M, de Graaf AO, ..., Jansen JH, Dugas M
- - (-) - [2018-06-26; online 2018-06-26]
Clinical Genomics Uppsala [Service]
Liquid Norbornadiene Photoswitches for Solar Energy Storage
Dreos A, Wang Z, Udmark J, ..., Nielsen MB, Moth-Poulsen K
Adv. Energy Mater. 8 (18) 1703401 [2018-06-00; online 2018-03-25]
Swedish NMR Centre (SNC) [Service]
The Properties of Amyloid-β Fibrils Are Determined by their Path of Formation
Brännström K, Islam T, Gharibyan AL, ..., Pamrén A, Olofsson A
Journal of Molecular Biology 430 (13) 1940-1949 [2018-06-00; online 2018-06-00]
Cryo-EM [Service]
Quantitation of Endogenous Metabolites in Mouse Tumors Using Mass-Spectrometry Imaging.
Swales JG, Dexter A, Hamm G, ..., Critchlow SE, Goodwin RJA
Anal. Chem. 90 (10) 6051-6058 [2018-05-15; online 2018-04-26]
Spatial Mass Spectrometry [Service]
Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells
Guzzi N, Cieśla M, Ngoc PCT, ..., Hsieh AC, Bellodi C
Cell 173 (5) 1204-1216.e26 [2018-05-00; online 2018-05-00]
Structural Proteomics [Service]
Identification of novel diagnostic biomarkers for deep venous thrombosis
Memon AA, Sundquist K, PirouziFard M, ..., Sundquist J, Zöller B
Br J Haematol 181 (3) 378-385 [2018-05-00; online 2018-04-19]
Clinical Biomarkers [Service]
Kynurenine pathway is altered in patients with SLE and associated with severe fatigue
Åkesson K, Pettersson S, Ståhl S, ..., Svenungsson E, Idborg H
Lupus Sci Med 5 (1) e000254 [2018-05-00; online 2018-05-23]
Swedish NMR Centre (SNC) [Collaborative]
Ethylene signaling induces gelatinous layers with typical features of tension wood in hybrid aspen
Felten J, Vahala J, Love J, ..., Mellerowicz EJ, Sundberg B
New Phytol 218 (3) 999-1014 [2018-05-00; online 2018-03-12]
Cryo-EM [Service]
Ultra-rapid auxin metabolite profiling for high-throughput mutant screening in Arabidopsis
Pěnčík A, Casanova-Sáez R, Pilařová V, ..., Ljung K, Novák O
- 69 (10) 2569-2579 [2018-04-27; online 2018-03-03]
Swedish Metabolomics Centre (SMC) [Service]
Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions
Spiess M, Hernandez-Varas P, Oddone A, ..., Lakadamyali M, Strömblad S
J. Cell Biol. - (-) jcb.201707075 [2018-04-09; online 2018-04-09]
Integrated Microscopy Technologies Stockholm [Collaborative]
Allele-selective RUNX1 binding regulates P1 blood group status by transcriptional control of A4GALT.
Westman JS, Stenfelt L, Vidovic K, ..., Kjellström S, Olsson ML
Blood 131 (14) 1611-1616 [2018-04-05; online 2018-02-08]
Structural Proteomics [Service]
Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor
Boerema AP, Aibara S, Paul B, ..., Lindahl E, Amunts A
NPLANTS 4 (4) 212-217 [2018-04-00; online 2018-04-02]
Cryo-EM [Service]
Peptide ion channel toxins from the bootlace worm, the longest animal on Earth.
Jacobsson E, Andersson HS, Strand M, ..., Tytgat J, Göransson U
Sci Rep 8 (1) 4596 [2018-03-22; online 2018-03-22]
Spatial Mass Spectrometry [Service]
Molecular mechanism of ATP versus GTP selectivity of adenylate kinase
Rogne P, Rosselin M, Grundström C, ..., Sauer UH, Wolf-Watz M
Proc Natl Acad Sci USA 115 (12) 3012-3017 [2018-03-20; online 2018-03-05]
Swedish NMR Centre (SNC) [Service]
Myopathy With SQSTM1 and TIA1 Variants: Clinical and Pathological Features.
Niu Z, Pontifex CS, Berini S, ..., Pfeffer G, Milone M
Front Neurol 9 (-) 147 [2018-03-19; online 2018-03-19]
Spatial Proteomics [Service]
Transcriptional stimulation of rate-limiting components of the autophagic pathway improves plant fitness
Minina EA, Moschou PN, Vetukuri RR, ..., Hofius D, Bozhkov PV
- 69 (6) 1415-1432 [2018-03-14; online 2018-01-20]
Swedish Metabolomics Centre (SMC) [Service]
Darkened leaves use different metabolic strategies for senescence and survival
Law SR, Chrobok D, Juvany M, ..., Gardestrom P, Keech O
Plant Physiol. - (-) pp.00062.2018 [2018-03-09; online 2018-03-09]
Swedish Metabolomics Centre (SMC) [Service]
Sexual dimorphism in the width of the mouse synaptonemal complex
Agostinho A, Kouznetsova A, Hernández-Hernández A, ..., Brismar H, Höög C
J Cell Sci 131 (5) jcs212548 [2018-03-01; online 2018-02-02]
Integrated Microscopy Technologies Stockholm [Collaborative]
Proteomic Profiling for Cardiovascular Biomarker Discovery in Orthostatic Hypotension
Johansson M, Ricci F, Aung N, ..., Melander O, Fedorowski A
Hypertension 71 (3) 465-472 [2018-03-00; online 2018-03-00]
Clinical Biomarkers [Service]
Galectin-3 levels relate in children to total body fat, abdominal fat, body fat distribution, and cardiac size
Dencker M, Arvidsson D, Karlsson MK, ..., Andersen LB, Thorsson O
Eur J Pediatr 177 (3) 461-467 [2018-03-00; online 2018-01-11]
Clinical Biomarkers [Service]
Current applications of antibody microarrays.
Chen Z, Dodig-Crnković T, Schwenk JM, Tao SC
Clin Proteomics 15 (-) 7 [2018-02-28; online 2018-02-28]
Affinity Proteomics Stockholm [Collaborative]
Dispersed Uniform Nanoparticles from a Macroscopic Organosilica Powder
Church TL, Bernin D, Garcia-Bennett AE, Hedin N
Langmuir 34 (6) 2274-2281 [2018-02-13; online 2018-02-05]
Swedish NMR Centre (SNC) [Collaborative]
Proteomic analyses identify prognostic biomarkers for pancreatic ductal adenocarcinoma.
Hu D, Ansari D, Pawłowski K, ..., Marko-Varga G, Andersson R
Oncotarget 9 (11) 9789-9807 [2018-02-09; online 2018-01-03]
Structural Proteomics [Service]
Human NUDT22 Is a UDP-Glucose/Galactose Hydrolase Exhibiting a Unique Structural Fold
Carter M, Jemth AS, Carreras-Puigvert J, ..., Helleday T, Stenmark P
Structure 26 (2) 295-303.e6 [2018-02-00; online 2018-02-00]
Protein Science Facility (PSF) [Service]
Establishment of Photosynthesis through Chloroplast Development Is Controlled by Two Distinct Regulatory Phases
Dubreuil C, Jin X, Barajas-López JdD, ..., Small I, Strand Å
Plant Physiol. 176 (2) 1199-1214 [2018-02-00; online 2017-06-16]
Cryo-EM [Service]
Quantitative image analysis of protein expression and colocalisation in skin sections
Zhang H, Ericsson M, Virtanen M, ..., Vahlquist A, Törmä H
Exp Dermatol 27 (2) 196-199 [2018-02-00; online 2018-01-09]
BioImage Informatics [Service]
Differential impact of RB status on E2F1 reprogramming in human cancer.
McNair C, Xu K, Mandigo AC, ..., Brown M, Knudsen KE
J. Clin. Invest. 128 (1) 341-358 [2018-01-02; online 2017-12-04]
Clinical Genomics Stockholm [Service]
Surface treatment of cellulose nanocrystals (CNC): effects on dispersion rheology
Sahlin K, Forsgren L, Moberg T, ..., Rigdahl M, Westman G
Cellulose 25 (1) 331-345 [2018-01-00; online 2017-11-28]
Swedish NMR Centre (SNC) [Collaborative]
Optimising methods for the recovery and quantification of di- and tripeptides in soil
J�mtg�rd S, Robinson N, Moritz T, Colgrave ML, Schmidt S
Soil Res. - (-) - [2018-00-00; online 2018-00-00]
Swedish Metabolomics Centre (SMC) [Service]
Synthesis of novel 1,2,4-thiadiazinane 1,1-dioxides via three component SuFEx type reaction
Khumalo MF, Akpan ED, Chinthakindi PK, ..., Naicker T, Arvidsson PI
RSC Adv. 8 (65) 37503-37507 [2018-00-00; online 2018-00-00]
Drug Discovery and Development (DDD) [Technology development]
Whole Slide Image Registration for the Study of Tumor Heterogeneity
Solorzano L, Almeida GM, Mesquita B, ..., Oliveira C, Wählby C
- - (-) 95-102 [2018-00-00; online 2018-09-14]
BioImage Informatics [Technology development]