Fluorescence Tissue Profiling

Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain.

Bazov I, Sarkisyan D, Kononenko O, ..., Yakovleva T, Bakalkin G

Cereb. Cortex 28 (9) 3129-3142 [2018-09-01; online 2017-10-03]

Bioinformatics Support for Computational Resources [Service] Fluorescence Tissue Profiling [Collaborative] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Year 2017

A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover.

Malenczyk K, Girach F, Szodorai E, ..., Groop L, Harkany T

EMBO J. 36 (14) 2107-2125 [2017-07-14; online 2017-06-21]

Injury Leads to the Appearance of Cells with Characteristics of Both Microglia and Astrocytes in Mouse and Human Brain.

Wilhelmsson U, Andersson D, de Pablo Y, ..., Pekny M, Pekna M

Cereb. Cortex 27 (6) 3360-3377 [2017-06-01; online 2017-04-12]

Fluorescence Tissue Profiling [Collaborative] Integrated Microscopy Technologies Gothenburg [Service]

An automated method measures variability in P-glycoprotein and ABCG2 densities across brain regions and brain matter.

Kannan P, Schain M, Kretzschmar WW, ..., Hall MD, Mulder J

J. Cereb. Blood Flow Metab. - (-) 271678X16660984 [2017-06-00; online 2016-08-05]

Fluorescence Tissue Profiling [Technology development]

FZD10-Gα13 signalling axis points to a role of FZD10 in CNS angiogenesis.

Hot B, Valnohova J, Arthofer E, ..., Mulder J, Schulte G

Cell. Signal. 32 (-) 93-103 [2017-04-00; online 2017-01-24]

Development of [(11)C]/[(3)H]THK-5351 - A potential novel carbon-11 tau imaging PET radioligand.

Stepanov V, Svedberg M, Jia Z, ..., Nordberg A, Halldin C

Nucl. Med. Biol. 46 (-) 50-53 [2017-03-00; online 2016-12-26]

Opioid precursor protein isoform is targeted to the cell nuclei in the human brain.

Kononenko O, Bazov I, Watanabe H, ..., Yakovleva T, Bakalkin G

Biochimica et Biophysica Acta (BBA) - General Subjects 1861 (2) 246-255 [2017-02-00; online 2016-11-10]

Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.

Romanov RA, Zeisel A, Bakker J, ..., Horvath TL, Harkany T

Nat. Neurosci. 20 (2) 176-188 [2017-02-00; online 2016-12-19]

Year 2016

CSF profiling of the human brain enriched proteome reveals associations of neuromodulin and neurogranin to Alzheimer's disease.

Remnestål J, Just D, Mitsios N, ..., Nilsson P, Häggmark-Månberg A

Proteomics Clin Appl 10 (12) 1242-1253 [2016-12-00; online 2016-10-10]

Affinity Proteomics Stockholm [Collaborative] Fluorescence Tissue Profiling [Collaborative]

Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer.

Mezheyeuski A, Bradic Lindh M, Guren TK, ..., Sorbye H, Östman A

Oncotarget 7 (27) 41948-41958 [2016-07-05; online 2016-06-02]

Fluorescence Tissue Profiling [Collaborative] Tissue Profiling [Collaborative]

Visualization and analysis of gene expression in tissue sections by spatial transcriptomics.

Ståhl PL, Salmén F, Vickovic S, ..., Lundeberg J, Frisén J

Science 353 (6294) 78-82 [2016-07-01; online 2016-07-02]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] Fluorescence Tissue Profiling [Collaborative] NGI Stockholm (Genomics Applications) [Collaborative] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Tissue Profiling [Collaborative]

Lesion Size Is Exacerbated in Hypoxic Rats Whereas Hypoxia-Inducible Factor-1 Alpha and Vascular Endothelial Growth Factor Increase in Injured Normoxic Rats: A Prospective Cohort Study of Secondary Hypoxia in Focal Traumatic Brain Injury.

Thelin EP, Frostell A, Mulder J, ..., Morganti-Kossmann MC, Bellander BM

Front Neurol 7 (-) 23 [2016-03-07; online 2016-03-07]

Anoctamin 2 identified as an autoimmune target in multiple sclerosis.

Ayoglu B, Mitsios N, Kockum I, ..., Olsson T, Nilsson P

Proc. Natl. Acad. Sci. U.S.A. 113 (8) 2188-2193 [2016-02-23; online 2016-02-09]

Autoimmunity and Serology Profiling [Collaborative] Fluorescence Tissue Profiling [Collaborative]

Year 2015

A secretagogin locus of the mammalian hypothalamus controls stress hormone release.

Romanov RA, Alpár A, Zhang MD, ..., Hökfelt T, Harkany T

EMBO J. 34 (1) 36-54 [2015-01-02; online 2014-11-27]

Year 2014

Evaluation of efficacy of a new MEK inhibitor, RO4987655, in human tumor xenografts by [(18)F] FDG-PET imaging combined with proteomic approaches.

Tegnebratt T, Ruge E, Bader S, ..., Tessier J, Stone-Elander S

EJNMMI Res 4 (1) 34 [2014-12-00; online 2014-09-09]

Affinity proteomic profiling of plasma, cerebrospinal fluid, and brain tissue within multiple sclerosis.

Byström S, Ayoglu B, Häggmark A, ..., Nilsson P, Schwenk JM

J. Proteome Res. 13 (11) 4607-4619 [2014-11-07; online 2014-09-19]

Affinity Proteomics Stockholm [Collaborative] Fluorescence Tissue Profiling

Visualization of angiogenesis during cancer development in the polyoma middle T breast cancer model: molecular imaging with (R)-[11C]PAQ.

Samén E, Lu L, Mulder J, ..., Rundqvist H, Stone-Elander S

EJNMMI Res 4 (1) 17 [2014-03-26; online 2014-03-26]

Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia and excitatory spinal neurons and are regulated by nerve injury.

Zhang MD, Tortoriello G, Hsueh B, ..., Harkany T, Hökfelt TG

Proc. Natl. Acad. Sci. U.S.A. 111 (12) E1149-E1158 [2014-03-25; online 2014-03-13]

Year 2013

Renal sensory and sympathetic nerves reinnervate the kidney in a similar time-dependent fashion after renal denervation in rats.

Mulder J, Hökfelt T, Knuepfer MM, Kopp UC

Am. J. Physiol. Regul. Integr. Comp. Physiol. 304 (8) R675-R682 [2013-04-15; online 2013-02-15]

Year 2012

Secretagogin is expressed in sensory CGRP neurons and in spinal cord of mouse and complements other calcium-binding proteins, with a note on rat and human.

Shi TJ, Xiang Q, Zhang MD, ..., Harkany T, Hökfelt T

Mol Pain 8 (-) 80 [2012-10-29; online 2012-10-29]

Year 2011

Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse.

Lindfors C, Nilsson IA, Garcia-Roves PM, ..., Schalling M, Johansen JE

Proc. Natl. Acad. Sci. U.S.A. 108 (44) 18108-18113 [2011-11-01; online 2011-10-26]

Characterization of NPY Y2 receptor protein expression in the mouse brain. II. Coexistence with NPY, the Y1 receptor, and other neurotransmitter-related molecules.

Stanić D, Mulder J, Watanabe M, Hökfelt T

J. Comp. Neurol. 519 (7) 1219-1257 [2011-05-01; online 2011-04-01]