Dispersed Uniform Nanoparticles from a Macroscopic Organosilica Powder.

Church TL, Bernin D, Garcia-Bennett AE, Hedin N

Langmuir 34 (6) 2274-2281 [2018-02-13; online 2018-02-05]

A colloidal dispersion of uniform organosilica nanoparticles could be produced via the disassembly of the non-surfactant-templated organosilica powder nanostructured folate material (NFM-1). This unusual reaction pathway was available because the folate and silica-containing moieties in NFM-1 are held together by noncovalent interactions. No precipitation was observed from the colloidal dispersion after a week, though particle growth occurred at a solvent-dependent rate that could be described by the Lifshitz-Slyozov-Wagner equation. An organosilica film that was prepared from the colloidal dispersion adsorbed folate-binding protein from solution but adsorbed ions from a phosphate-buffered saline solution to a larger degree. To our knowledge, this is the first instance of a colloidal dispersion of organosilica nanoparticles being derived from a macroscopic material rather than from molecular precursors.

Swedish NMR Centre (SNC) [Collaborative]

PubMed 29400064

DOI 10.1021/acs.langmuir.7b03705

Crossref 10.1021/acs.langmuir.7b03705

Publications 9.5.0