Publications 2016

664 publications

Zebrafish (Danio rerio) behaviour is largely unaffected by elevated pCO2.
Vossen LE, Jutfelt F, Cocco A, Thörnqvist P, Winberg S
Conserv Physiol 4 (1) cow065 [2016-12-29; online 2016-12-29]
Genome Engineering Zebrafish [Service]
The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.
van Kempen LC, Redpath M, Elchebly M, ..., Feunteun J, Spatz A
Sci Transl Med 8 (369) 369ra177 [2016-12-14; online 2016-12-16]
Tissue Profiling [Collaborative]
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
Mansouri L, Noerenberg D, Young E, ..., Rosenquist R, Damm F
Blood 128 (23) 2666-2670 [2016-12-08; online 2016-09-26]
Clinical Genomics Uppsala [Collaborative]
An oxygen-sensitive toxin-antitoxin system.
Marimon O, Teixeira JM, Cordeiro TN, ..., Wood TK, Pons M
Nat Commun 7 (-) 13634 [2016-12-08; online 2016-12-08]
Swedish NMR Centre (SNC) [Collaborative]
Iron chelators target both proliferating and quiescent cancer cells.
Fryknäs M, Zhang X, Bremberg U, ..., Linder S, Larsson R
Sci Rep 6 (-) 38343 [2016-12-07; online 2016-12-07]
Drug Discovery and Development (DDD) [Service]
Study on genetic stability in human urothelial cells in vitro.
Chamorro CI, Zeiai S, Reinfeldt Engberg G, ..., Nordenskjöld A, Fossum M
J Tissue Eng Regen Med - (-) - [2016-11-12; online 2016-11-12]
Bioinformatics and Expression Analysis (BEA) [Service]
Case-specific potentiation of glioblastoma drugs by pterostilbene.
Schmidt L, Baskaran S, Johansson P, ..., Krona C, Nelander S
Oncotarget 7 (45) 73200-73215 [2016-11-08; online 2016-10-01]
Drug Discovery and Development (DDD) [Collaborative]
Looking for Missing Proteins in the Proteome of Human Spermatozoa: An Update.
Vandenbrouck Y, Lane L, Carapito C, ..., Garin J, Pineau C
J. Proteome Res. 15 (11) 3998-4019 [2016-11-04; online 2016-08-23]
Tissue Profiling [Collaborative]
The H3 chaperone function of NASP is conserved in Arabidopsis.
Maksimov V, Nakamura M, Wildhaber T, ..., Bergquist J, Hennig L
Plant J. 88 (3) 425-436 [2016-11-00; online 2016-09-15]
Mass Spectrometry-based Proteomics, Uppsala [Collaborative]
Long-term outcome in young women with breast cancer: a population-based study.
Fredholm H, Magnusson K, Lindström LS, ..., Frisell J, Fredriksson I
Breast Cancer Res. Treat. 160 (1) 131-143 [2016-11-00; online 2016-09-13]
Tissue Profiling [Collaborative]
A ribonucleotide reductase inhibitor with deoxyribonucleoside-reversible cytotoxicity.
Crona M, Codó P, Jonna VR, ..., Fernandes AP, Tholander F
Mol Oncol 10 (9) 1375-1386 [2016-11-00; online 2016-07-26]
Protein Science Facility (PSF) [Service]
(13)C NMR assignments of regenerated cellulose from solid-state 2D NMR spectroscopy.
Idström A, Schantz S, Sundberg J, ..., Gatenholm P, Nordstierna L
Carbohydr Polym 151 (-) 480-487 [2016-10-20; online 2016-05-31]
Swedish NMR Centre (SNC) [Service]
High-Throughput Analysis of the Plasma N-Glycome by UHPLC.
Adamczyk B, Stöckmann H, O'Flaherty R, Karlsson NG, Rudd PM
Methods Mol. Biol. 1503 (-) 97-108 [2016-10-16; online 2016-10-16]
Glycoproteomics and MS Proteomics [Technology development]
Databases and Associated Tools for Glycomics and Glycoproteomics.
Lisacek F, Mariethoz J, Alocci D, ..., Jin C, Karlsson NG
Methods Mol. Biol. 1503 (-) 235-264 [2016-10-16; online 2016-10-16]
Glycoproteomics and MS Proteomics [Collaborative]
Supersaturation of poorly soluble drugs induced by mesoporous magnesium carbonate.
Zhang P, Zardán Gómez de la Torre T, Welch K, Bergström C, Strømme M
Eur J Pharm Sci 93 (-) 468-474 [2016-10-10; online 2016-08-31]
BioMaterial Interactions (BioMat) [Service]
Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism.
Jia M, Andreassen T, Jensen L, ..., Moestue SA, Dahlman-Wright K
Cancer Res. 76 (19) 5634-5646 [2016-10-01; online 2016-07-28]
Swedish Metabolomics Centre (SMC) [Service]
Direct acquisition of organic N by white clover even in the presence of inorganic N
Czaban W, Jämtgård S, Näsholm T, ..., Nicolaisen M, Fomsgaard IS
Plant Soil 407 (1-2) 91-107 [2016-10-00; online 2016-04-15]
Swedish Metabolomics Centre (SMC) [Service]
A proposal for validation of antibodies.
Uhlen M, Bandrowski A, Carr S, ..., Snyder M, Yamamoto T
Nat. Methods 13 (10) 823-827 [2016-10-00; online 2016-09-05]
Spatial Proteomics [Collaborative]
Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome.
Butler LM, Hallström BM, Fagerberg L, ..., Renné T, Odeberg J
Cell Syst 3 (3) 287-301.e3 [2016-09-28; online 2016-09-15]
Tissue Profiling [Collaborative]
Naphthalene Derivatives from the Roots of Pentas parvifolia and Pentas bussei.
Abdissa N, Pan F, Gruhonjic A, ..., Yenesew A, Erdélyi M
J. Nat. Prod. 79 (9) 2181-2187 [2016-09-23; online 2016-08-12]
Swedish NMR Centre (SNC) [Service]
Genetic Spectrum of Idiopathic Restrictive Cardiomyopathy Uncovered by Next-Generation Sequencing.
Kostareva A, Kiselev A, Gudkova A, ..., Sejersen T, Shlyakhto E
PLoS ONE 11 (9) e0163362 [2016-09-23; online 2016-09-23]
Clinical Genomics Stockholm [Service]
Linkage between Fitness of Yeast Cells and Adenylate Kinase Catalysis
Tükenmez H, Magnussen HM, Kovermann M, Byström A, Wolf-Watz M
PLoS ONE 11 (9) e0163115 [2016-09-19; online 2016-09-19]
Swedish NMR Centre (SNC) [Service]
Tissue microarray profiling in human heart failure.
Lal S, Nguyen L, Tezone R, ..., Li A, Dos Remedios C
Proteomics 16 (17) 2319-2326 [2016-09-00; online 2016-08-11]
Tissue Profiling [Collaborative]
Exploring structure and interactions of the bacterial adaptor protein YjbH by crosslinking mass spectrometry.
Al-Eryani Y, Ib Rasmussen M, Kjellström S, ..., Emanuelsson C, von Wachenfeldt C
Proteins 84 (9) 1234-1245 [2016-09-00; online 2016-06-15]
Structural Proteomics [Service]
Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond.
Rosenquist R, Rosenwald A, Du MQ, ..., Stamatopoulos K, European Research Initiative on CLL (ERIC) and the European Association for Haematopathology (EAHP)
Haematologica 101 (9) 1002-1009 [2016-09-00; online 2016-09-02]
Clinical Genomics Uppsala [Collaborative]
Autoantibody targets in vaccine-associated narcolepsy.
Häggmark-Månberg A, Zandian A, Forsström B, ..., Olsson T, Nilsson P
Autoimmunity 49 (6) 421-433 [2016-09-00; online 2016-05-20]
Autoimmunity and Serology Profiling [Collaborative]
Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity.
Ahmad S, Ytterberg AJ, Thulasingam M, ..., Rinaldo-Matthis A, Haeggström JZ
J. Biol. Chem. 291 (35) 18410-18418 [2016-08-26; online 2016-06-30]
Advanced Mass Spectrometry Proteomics [Collaborative]
Substituent Effects on the [N-I-N](+) Halogen Bond.
Carlsson AC, Mehmeti K, Uhrbom M, ..., Rissanen K, Erdélyi M
J. Am. Chem. Soc. 138 (31) 9853-9863 [2016-08-10; online 2016-06-17]
Swedish NMR Centre (SNC) [Service]
ω-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease: Pooling Project of 19 Cohort Studies.
Del Gobbo LC, Imamura F, Aslibekyan S, ..., Mozaffarian D, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCe)
JAMA Intern Med 176 (8) 1155-1166 [2016-08-01; online 2016-07-01]
Bioinformatics Support for Computational Resources [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]
Profilin connects actin assembly with microtubule dynamics.
Nejedla M, Sadi S, Sulimenko V, ..., Aspenström P, Karlsson R
Mol. Biol. Cell 27 (15) 2381-2393 [2016-08-01; online 2016-06-17]
Integrated Microscopy Technologies Stockholm [Collaborative]
Kinetic investigation of human 5-lipoxygenase with arachidonic acid.
Mittal M, Kumar RB, Balagunaseelan N, ..., Haeggström JZ, Rinaldo-Matthis A
Bioorg. Med. Chem. Lett. 26 (15) 3547-3551 [2016-08-01; online 2016-06-11]
Protein Science Facility (PSF) [Service]
SATB2 is expressed in Merkel cell carcinoma.
Fukuhara M, Agnarsdóttir M, Edqvist PH, Coter A, Ponten F
Arch. Dermatol. Res. 308 (6) 449-454 [2016-08-00; online 2016-06-04]
Tissue Profiling [Technology development]
Intra-tumour IgA1 is common in cancer and is correlated with poor prognosis in bladder cancer.
Welinder C, Jirström K, Lehn S, ..., Danielsson L, Jansson B
Heliyon 2 (8) e00143 [2016-08-00; online 2016-08-16]
Structural Proteomics [Service]
Effects of Fluoxetine on Human Embryo Development.
Kaihola H, Yaldir FG, Hreinsson J, ..., Åkerud H, Sundström-Poromaa I
Front Cell Neurosci 10 (-) 160 [2016-06-16; online 2016-06-16]
Mass Spectrometry-based Proteomics, Uppsala [Collaborative]
Elevated levels of FN1 and CCL2 in bronchoalveolar lavage fluid from sarcoidosis patients.
Hamsten C, Wiklundh E, Grönlund H, ..., Grunewald J, Häggmark-Månberg A
Respir. Res. 17 (1) 69 [2016-06-04; online 2016-06-04]
Affinity Proteomics Stockholm [Collaborative]
Common and Rare Genetic Variation in CCR2, CCR5, or CX3CR1 and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic Traits.
Golbus JR, Stitziel NO, Zhao W, ..., Reilly MP, CARDIoGRAMplusC4D, Myocardial Infarction Genetics (MIGen), Exome Sequencing Project and Early-Onset Myocardial Infarction (ESP EOMI), and the Pakistan Risk of Myocardial Infarction Study (PROMIS) Consortia*
Circ Cardiovasc Genet 9 (3) 250-258 [2016-06-00; online 2016-03-26]
NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]
Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma.
Roy A, Femel J, Huijbers EJ, ..., Olsson AK, Åbrink M
PLoS ONE 11 (5) e0156151 [2016-05-25; online 2016-05-25]
Array and Analysis Facility [Service]
New technologies for DNA analysis--a review of the READNA Project.
McGinn S, Bauer D, Brefort T, ..., Willcocks JP, Gut IG
N Biotechnol 33 (3) 311-330 [2016-05-25; online 2015-10-26]
Clinical Genomics Uppsala [Collaborative]
Chroman-4-one and chromone based somatostatin β-turn mimetics.
Fridén-Saxin M, Seifert T, Malo M, ..., Grøtli M, Luthman K
Eur J Med Chem 114 (-) 59-64 [2016-05-23; online 2016-02-21]
Swedish NMR Centre (SNC) [Service]
A Population Shift between Sparsely Populated Folding Intermediates Determines Amyloidogenicity.
Karamanos TK, Pashley CL, Kalverda AP, ..., Orekhov VY, Radford SE
J. Am. Chem. Soc. 138 (19) 6271-6280 [2016-05-18; online 2016-05-06]
Swedish NMR Centre (SNC) [Collaborative]
A combined computational and structural model of the full-length human prolactin receptor.
Bugge K, Papaleo E, Haxholm GW, ..., Lindorff-Larsen K, Kragelund BB
Nat Commun 7 (-) 11578 [2016-05-13; online 2016-05-13]
Swedish NMR Centre (SNC) [Service]
Divergent non-heme iron enzymes in the nogalamycin biosynthetic pathway.
Siitonen V, Selvaraj B, Niiranen L, ..., Schneider G, Metsä-Ketelä M
Proc. Natl. Acad. Sci. U.S.A. 113 (19) 5251-5256 [2016-05-10; online 2016-04-25]
Protein Science Facility (PSF) [Service]
The Effects of High Steady State Auxin Levels on Root Cell Elongation in Brachypodium.
Pacheco-Villalobos D, Díaz-Moreno SM, van der Schuren A, ..., Bulone V, Hardtke CS
Plant Cell - (-) - [2016-05-05; online 2016-05-05]
Swedish Metabolomics Centre (SMC) [Service]
TOR Signaling and Nutrient Sensing.
Dobrenel T, Caldana C, Hanson J, ..., Veit B, Meyer C
Annu Rev Plant Biol 67 (-) 261-285 [2016-04-29; online 2016-02-26]
Swedish Metabolomics Centre (SMC) [Service]
Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells.
Bourseau-Guilmain E, Menard JA, Lindqvist E, ..., Welinder C, Belting M
Nat Commun 7 (-) 11371 [2016-04-20; online 2016-04-20]
Structural Proteomics [Service]
Single-cell transcriptome analysis of endometrial tissue.
Krjutškov K, Katayama S, Saare M, ..., Salumets A, Kere J
Hum. Reprod. 31 (4) 844-853 [2016-04-00; online 2016-02-13]
Bioinformatics and Expression Analysis (BEA) [Service]
A saposin-lipoprotein nanoparticle system for membrane proteins.
Frauenfeld J, Löving R, Armache JP, ..., Cheng Y, Nordlund P
Nat. Methods 13 (4) 345-351 [2016-04-00; online 2016-03-07]
Protein Science Facility (PSF) [Service]
A Facile Synthesis of NODASA-Functionalized Peptide
Naicker T, Albericio F, Dutta J, ..., Kruger H, Govender T
Synlett 27 (11) 1685-1688 [2016-03-30; online 2016-03-30]
Drug Discovery and Development (DDD) [Collaborative]
System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis.
Pozniak Y, Balint-Lahat N, Rudolph JD, ..., Barshack I, Geiger T
Cell Syst 2 (3) 172-184 [2016-03-23; online 2016-03-03]
Tissue Profiling [Collaborative]
On-Water Synthesis of Biaryl Sulfonyl Fluorides.
Chinthakindi PK, Kruger HG, Govender T, Naicker T, Arvidsson PI
J. Org. Chem. 81 (6) 2618-2623 [2016-03-18; online 2016-02-24]
Drug Discovery and Development (DDD) [Collaborative]
Thiazolino 2-Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity.
Good JA, Silver J, Núñez-Otero C, ..., Bergström S, Almqvist F
J. Med. Chem. 59 (5) 2094-2108 [2016-03-10; online 2016-02-22]
Chemical Biology Consortium Sweden (CBCS) [Collaborative]
Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease.
Khoonsari PE, Häggmark A, Lönnberg M, ..., Kultima K, Shevchenko G
PLoS ONE 11 (3) e0150672 [2016-03-07; online 2016-03-07]
Affinity Proteomics Stockholm [Collaborative]
Disruption of POGZ Is Associated with Intellectual Disability and Autism Spectrum Disorders.
Stessman HA, Willemsen MH, Fenckova M, ..., Eichler EE, Kleefstra T
Am. J. Hum. Genet. 98 (3) 541-552 [2016-03-03; online 2016-03-05]
Clinical Genomics Stockholm [Service]
Oncogene-Induced Senescence in Pituitary Adenomas--an Immunohistochemical Study.
Manojlovic-Gacic E, Skender-Gazibara M, Popovic V, ..., Pontén F, Casar-Borota O
Endocr. Pathol. 27 (1) 1-11 [2016-03-00; online 2015-11-18]
Tissue Profiling [Collaborative]
Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?
Pospisilova S, Sutton LA, Malcikova J, ..., Ghia P, European Research Initiative on CLL (ERIC)
Haematologica 101 (3) 263-265 [2016-03-00; online 2016-03-02]
Clinical Genomics Uppsala [Service]
Characterization of genetic variation in TLR8 in relation to allergic rhinitis.
Henmyr V, Lind-Halldén C, Carlberg D, ..., Säll T, Cardell LO
Allergy 71 (3) 333-341 [2016-03-00; online 2015-11-12]
Mutation Analysis Facility (MAF)
Biochemical Conversion of Torrefied Norway Spruce After Pretreatment with Acid or Ionic Liquid
Normark M, Pommer L, Gräsvik J, ..., Winestrand S, Jönsson LJ
Bioenerg. Res. 9 (1) 355-368 [2016-03-00; online 2015-11-26]
Swedish NMR Centre (SNC) [Collaborative]
Efficient Isotope Editing of Proteins for Site-Directed Vibrational Spectroscopy.
Peuker S, Andersson H, Gustavsson E, ..., Erdelyi M, Westenhoff S
J. Am. Chem. Soc. 138 (7) 2312-2318 [2016-02-24; online 2016-02-10]
Swedish NMR Centre (SNC) [Collaborative]
Stereoselective synthesis towards unnatural proline based amino acids
S.Makhathini S, Das SK, Singh T, ..., Govender T, Naicker T
ARKIVOC 2016 (3) 134-144 [2016-02-07; online 2016-02-07]
Drug Discovery and Development (DDD) [Collaborative]
Systems Proteomics View of the Endogenous Human Claudin Protein Family.
Liu F, Koval M, Ranganathan S, ..., Kelleher NL, Baker MS
J. Proteome Res. 15 (2) 339-359 [2016-02-05; online 2016-01-12]
Spatial Proteomics [Service]
Elucidating the Molecular Composition of Cartilage by Proteomics.
Hsueh MF, Khabut A, Kjellström S, Önnerfjord P, Kraus VB
J. Proteome Res. 15 (2) 374-388 [2016-02-05; online 2016-01-15]
Structural Proteomics [Service]
Tissue sample stability: thawing effect on multi-organ samples
Torell F, Bennett K, Cereghini S, ..., Trygg J, Lundstedt T
Metabolomics 12 (2) - [2016-02-00; online 2015-12-31]
Swedish Metabolomics Centre (SMC) [Service]
The C repressor of the P2 bacteriophage.
Massad T, Papadopolos E, Stenmark P, Damberg P
J. Biomol. NMR 64 (2) 175-180 [2016-02-00; online 2015-12-22]
Swedish NMR Centre (SNC) [Service]
Diffusion-Controlled Drug Release From the Mesoporous Magnesium Carbonate Upsalite(®).
Zhang P, Zardán Gómez de la Torre T, Forsgren J, Bergström CA, Strømme M
J Pharm Sci 105 (2) 657-663 [2016-02-00; online 2015-06-20]
BioMaterial Interactions (BioMat)
Metabolites in Blood for Prediction of Bacteremic Sepsis in the Emergency Room.
Kauppi AM, Edin A, Ziegler I, ..., Strålin K, Johansson A
PLoS ONE 11 (1) e0147670 [2016-01-22; online 2016-01-22]
Swedish Metabolomics Centre (SMC) [Service]
Backbone Assignment of the MALT1 Paracaspase by Solution NMR.
Unnerståle S, Nowakowski M, Baraznenok V, ..., Orekhov V, Agback T
PLoS ONE 11 (1) e0146496 [2016-01-20; online 2016-01-20]
Swedish NMR Centre (SNC) [Collaborative]
The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling.
Raja E, Tzavlaki K, Vuilleumier R, ..., Heldin CH, Moustakas A
Oncotarget 7 (2) 1120-1143 [2016-01-12; online 2015-12-25]
Clinical Genomics Uppsala [Collaborative]
The 5300-year-old Helicobacter pylori genome of the Iceman.
Maixner F, Krause-Kyora B, Turaev D, ..., Rattei T, Zink A
Science 351 (6269) 162-165 [2016-01-08; online 2016-01-09]
Clinical Genomics Stockholm [Collaborative]
Characterization and Expression of the Zebrafish qki Paralogs.
Radomska KJ, Sager J, Farnsworth B, ..., Jazin E, Emilsson LS
PLoS ONE 11 (1) e0146155 [2016-01-04; online 2016-01-04]
Genome Engineering Zebrafish [Service]
GREM1 and POLE variants in hereditary colorectal cancer syndromes.
Rohlin A, Eiengård F, Lundstam U, ..., Björk J, Nordling M
Genes Chromosomes Cancer 55 (1) 95-106 [2016-01-00; online 2015-10-23]
Swedish NMR Centre (SNC) [Collaborative]
NMR analysis of the human saliva metabolome distinguishes dementia patients from matched controls
Figueira J, Jonsson P, Nordin Adolfsson A, ..., Nyberg L, Öhman A
Mol. BioSyst. 12 (8) 2562-2571 [2016-00-00; online 2016-00-00]
Swedish NMR Centre (SNC) [Collaborative]

Publications 9.5.0