Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1

Llona-Minguez S, Höglund A, Jacques SA, Johansson L, Calderón-Montaño JM, Claesson M, Loseva O, Valerie NCK, Lundbäck T, Piedrafita J, Maga G, Crespan E, Meijer L, Burgos Morón E, Baranczewski P, Hagbjörk AL, Svensson R, Wiita E, Almlöf I, Visnes T, Jeppsson F, Sigmundsson K, Jensen AJ, Artursson P, Jemth AS, Stenmark P, Warpman Berglund U, Scobie M, Helleday T

J. Med. Chem. 59 (3) 1140-1148 [2016-02-11; online 2016-02-11]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

Drug Discovery and Development (DDD) [Collaborative]

Protein Science Facility (PSF) [Service]

QC bibliography QC xrefs

PubMed 26771665

DOI 10.1021/acs.jmedchem.5b01741

Crossref 10.1021/acs.jmedchem.5b01741

Laboratories for Chemical Biology at Karolinska Institutet (LCBKI)
Uppsala Drug Optimization and Pharmaceutical Profiling (UDOPP)