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Varghese OP, Liu J, Sundaram K, Hilborn J, Oommen OP
Biomater Sci 4 (9) 1310-1313 [2016-08-16; online 2016-07-20]
Glycosaminoglycan derived nanoparticles are a promising delivery system owing to their unique tumour targeting ability. Exploiting fluorescein for inducing amphiphilicity in these biopolymers provides inherent imaging and drug stabilization capabilities by π-π stacking interactions with aromatic antineoplastic agents. This offers a versatile and highly customizable nanocarrier with narrow size distribution and high drug loading efficiency (80%) with sustained drug release.
Karolinska High Throughput Center (KHTC) [Service]
PubMed 27431007
DOI 10.1039/c6bm00335d
Crossref 10.1039/c6bm00335d