Data on the expression of cellular lncRNAs in human adenovirus infected cells.

Chen M, Zhao H, Lind SB, Pettersson U

Data Brief 8 (-) 1263-1279 [2016-09-00; online 2016-08-23]

Expression of cellular long non-coding RNAs (lncRNAs) in human primary lung fibroblasts (IMR-90) during the course of adenovirus type 2 (Ad2) infection was studied by strand-specific whole transcriptome sequencing. In total, 645 cellular lncRNAs were expressed at a significant level and 398 of them were changed more than 2-fold. The changes in expression followed a distinct temporal pattern. Significantly, 80% of the changes occurred at the late phase and 80% of the de-regulated lncRNAs were up-regulated. The three largest groups of deregulated lncRNAs were 125 antisense RNAs, 111 pseudogenes and 85 long intergenic non-coding RNAs (lincRNAs). Lastly, more than 36% of lncRNAs have been shown to interact with RNA binding proteins.

Bioinformatics Compute and Storage [Service]

NGI Uppsala (SNP&SEQ Technology Platform) [Service]

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PubMed 27547808

DOI 10.1016/j.dib.2016.06.053

Crossref 10.1016/j.dib.2016.06.053

S2352-3409(16)30421-8

pmc PMC4983107