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Teixeira PF, Kmiec B, Branca RM, Murcha MW, Byzia A, Ivanova A, Whelan J, Drag M, Lehtiö J, Glaser E
Nat. Chem. Biol. 13 (1) 15-17 [2017-01-00; online 2016-10-31]
Plastids (including chloroplasts) are subcellular sites for a plethora of proteolytic reactions, required in functions ranging from protein biogenesis to quality control. Here we show that peptides generated from pre-protein maturation within chloroplasts of Arabidopsis thaliana are degraded to amino acids by a multi-step peptidolytic cascade consisting of oligopeptidases and aminopeptidases, effectively allowing the recovery of single amino acids within these organelles.
Clinical Proteomics Mass spectrometry [Collaborative]
Global Proteomics and Proteogenomics [Collaborative]
Swedish Metabolomics Centre (SMC) [Service]
PubMed 27820795
DOI 10.1038/nchembio.2227
Crossref 10.1038/nchembio.2227
pii: nchembio.2227