Publications 2015

375 publications

PubMed DOI Crossref
Exploring water as building bricks in enzyme engineering.
Hendil-Forssell P, Martinelle M, Syrén PO
Chem. Commun. (Camb.) 51 (97) 17221-17224 [2015-12-18; online 2015-10-02]
Protein Science Facility
PubMed DOI Crossref
Protein profiling reveals consequences of lifestyle choices on predicted biological aging.
Enroth S, Enroth SB, Johansson Å, Gyllensten U
Sci Rep 5 (-) 17282 [2015-12-01; online 2015-12-01]
Clinical Biomarkers
PubMed DOI Crossref
Bacterial diversity along a 2600 km river continuum.
Savio D, Sinclair L, ..., Farnleitner AH, Eiler A
Environ. Microbiol. 17 (12) 4994-5007 [2015-12-00; online 2015-04-30]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Identification of proteins from human permanent erupted enamel.
Castiblanco GA, Rutishauser D, ..., Castellanos JE, Mejía W
Eur. J. Oral Sci. 123 (6) 390-395 [2015-12-00; online 2015-10-04]
Advanced Mass Spectrometry Proteomics
PubMed DOI Crossref
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Gaulton KJ, Ferreira T, ..., Morris AP, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Nat. Genet. 47 (12) 1415-1425 [2015-12-00; online 2015-11-10]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Discovery of New Risk Markers for Ischemic Stroke Using a Novel Targeted Proteomics Chip.
Lind L, Siegbahn A, ..., Sundström J, Ärnlöv J
Stroke 46 (12) 3340-3347 [2015-12-00; online 2015-11-07]
Clinical Biomarkers
PubMed DOI Crossref
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
Paternoster L, Standl M, ..., Weidinger S, EArly Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium
Nat. Genet. 47 (12) 1449-1456 [2015-12-00; online 2015-10-21]
Mutation Analysis Facility (MAF)
PubMed DOI Crossref
Immunocapture strategies in translational proteomics.
Fredolini C, Byström S, ..., Nilsson P, Schwenk JM
Expert Rev Proteomics 13 (1) 83-98 [2015-11-11; online 2015-11-11]
Plasma Profiling
PubMed DOI Crossref
Meta-analysis identifies seven susceptibility loci involved in the atopic march.
Marenholz I, Esparza-Gordillo J, ..., Henderson AJ, Lee YA
Nat Commun 6 (-) 8804 [2015-11-06; online 2015-11-06]
Mutation Analysis Facility (MAF)
PubMed DOI Crossref
Quantitative proteogenomics of human pathogens using DIA-MS.
Malmström L, Bakochi A, ..., Karlsson C, Malmström J
J Proteomics 129 (-) 98-107 [2015-11-03; online 2015-09-19]
Bioinformatics Short-term Support and Infrastructure (BILS)
PubMed DOI Crossref
Mutation in CEP63 co-segregating with developmental dyslexia in a Swedish family.
Einarsdottir E, Svensson I, ..., Kere J, Matsson H
Hum. Genet. 134 (11-12) 1239-1248 [2015-11-00; online 2015-09-25]
NGI Uppsala (Uppsala Genome Center)
PubMed DOI Crossref
Membrane vesicle-mediated release of bacterial RNA.
Sjöström AE, Sandblad L, Uhlin BE, Wai SN
Sci Rep 5 (-) 15329 [2015-10-20; online 2015-10-20]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation.
Gustafsson Sheppard N, Jarl L, ..., Jain M, Nilsson R
Sci Rep 5 (-) 15029 [2015-10-13; online 2015-10-13]
Cell Profiling
DOI Crossref
Acid-Base Catalyst Discriminates between a Fructose 6-Phosphate Aldolase and a Transaldolase
Stellmacher L, Sandalova T, ..., Sprenger GA, Samland AK
ChemCatChem 7 (19) 3140-3151 [2015-10-00; online 2015-08-06]
Protein Science Facility
PubMed DOI Crossref
Trimeric microsomal glutathione transferase 2 displays one third of the sites reactivity.
Ahmad S, Thulasingam M, ..., Haeggström JZ, Rinaldo-Matthis A
Biochim. Biophys. Acta 1854 (10 Pt A) 1365-1371 [2015-10-00; online 2015-06-13]
Protein Science Facility
PubMed DOI Crossref
A New Method for Detecting Associations with Rare Copy-Number Variants.
Tzeng JY, Magnusson PK, ..., Swedish Schizophrenia Consortium , Szatkiewicz JP
PLoS Genet. 11 (10) e1005403 [2015-10-00; online 2015-10-02]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
The effects of age and gender on plasma levels of 63 cytokines.
Larsson A, Carlsson L, ..., Thulin M, Kamali-Moghaddam M
J. Immunol. Methods 425 (-) 58-61 [2015-10-00; online 2015-06-17]
Clinical Biomarkers
PubMed DOI Crossref
Dormant phages of Helicobacter pylori reveal distinct populations in Europe.
Vale FF, Vadivelu J, ..., Mégraud F, Lehours P
Sci Rep 5 (-) 14333 [2015-09-21; online 2015-09-21]
Clinical Genomics
PubMed DOI Crossref
Gene expression profiling of pre-eclamptic placentae by RNA sequencing.
Kaartokallio T, Cervera A, ..., Laivuori H, FINNPEC Core Investigator Group
Sci Rep 5 (-) 14107 [2015-09-21; online 2015-09-21]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)
PubMed DOI Crossref
Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing.
Parry M, Rose-Zerilli MJ, ..., Oscier D, Strefford JC
Clin. Cancer Res. 21 (18) 4174-4183 [2015-09-15; online 2015-03-18]
Clinical Sequencing
PubMed DOI Crossref
Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project.
Horvatovich P, Lundberg EK, ..., Paik YK, Hancock WS
J. Proteome Res. 14 (9) 3415-3431 [2015-09-04; online 2015-06-16]
Cell Profiling
PubMed DOI Crossref
Transcriptomics of colour patterning and coloration shifts in crows.
Poelstra JW, Vijay N, Hoeppner MP, Wolf JB
Mol. Ecol. 24 (18) 4617-4628 [2015-09-00; online 2015-08-25]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
In Vitro and In Vivo Response to Low-Modulus PMMA-Based Bone Cement.
Carlsson E, Mestres G, ..., Larsson S, Persson C
Biomed Res Int 2015 (-) 594284 [2015-08-20; online 2015-08-20]
BioMaterial Interactions (BioMat)
PubMed DOI Crossref
Comprehensive genomic profiles of small cell lung cancer.
George J, Lim JS, ..., Sage J, Thomas RK
Nature 524 (7563) 47-53 [2015-08-06; online 2015-07-15]
Clinical Sequencing
PubMed DOI Crossref
Heat differentiated complement factor profiling.
Hamsten C, Skattum L, ..., Nilsson P, Neiman M
J Proteomics 126 (-) 155-162 [2015-08-03; online 2015-06-07]
Plasma Profiling
PubMed DOI Crossref
Effect of genetic variations on ticagrelor plasma levels and clinical outcomes.
Varenhorst C, Eriksson N, ..., Wallentin L, PLATO Investigators
Eur. Heart J. 36 (29) 1901-1912 [2015-08-01; online 2015-05-04]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Directional dominance on stature and cognition in diverse human populations.
Joshi PK, Esko T, ..., Polašek O, Wilson JF
Nature 523 (7561) 459-462 [2015-07-23; online 2015-07-02]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Scaffolding of a bacterial genome using MinION nanopore sequencing.
Karlsson E, Lärkeryd A, ..., Forsman M, Stenberg P
Sci Rep 5 (-) 11996 [2015-07-07; online 2015-07-07]
NGI Uppsala (Uppsala Genome Center)
PubMed DOI Crossref
CTCF/cohesin-binding sites are frequently mutated in cancer.
Katainen R, Dave K, ..., Taipale J, Aaltonen LA
Nat. Genet. 47 (7) 818-821 [2015-07-00; online 2015-06-09]
Karolinska High Throughput Center (KHTC)
PubMed DOI Crossref
Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate.
Trésaugues L, Lundbäck T, ..., Gräslund S, Nordlund P
PLoS ONE 10 (6) e0131507 [2015-06-29; online 2015-06-29]
Protein Science Facility
PubMed DOI Crossref
Structure of the nuclease subunit of human mitochondrial RNase P.
Reinhard L, Sridhara S, Hällberg BM
Nucleic Acids Res. 43 (11) 5664-5672 [2015-06-23; online 2015-05-09]
Protein Science Facility
PubMed DOI Crossref
Dynamics of Cell Generation and Turnover in the Human Heart.
Bergmann O, Zdunek S, ..., Druid H, Frisén J
Cell 161 (7) 1566-1575 [2015-06-18; online 2015-06-16]
Advanced Light Microscopy
PubMed DOI Crossref
Evolutionary analysis of the female-specific avian W chromosome.
Smeds L, Warmuth V, ..., Török J, Ellegren H
Nat Commun 6 (-) 7330 [2015-06-04; online 2015-06-04]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Human adaptation to arsenic-rich environments.
Schlebusch CM, Gattepaille LM, ..., Jakobsson M, Broberg K
Mol. Biol. Evol. 32 (6) 1544-1555 [2015-06-00; online 2015-03-06]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Zebrafish: A possible tool to evaluate bioactive ions.
Montazerolghaem M, Nyström L, Engqvist H, Karlsson Ott M
Acta Biomater 19 (-) 10-14 [2015-06-00; online 2015-03-17]
Zebrafish
PubMed DOI Crossref
The impact of low-frequency and rare variants on lipid levels.
Surakka I, Horikoshi M, ..., Ripatti S, ENGAGE Consortium
Nat. Genet. 47 (6) 589-597 [2015-06-00; online 2015-05-12]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Phylogeny, evolution and classification of gall wasps: the plot thickens.
Ronquist F, Nieves-Aldrey JL, ..., Liljeblad J, Nylander JA
PLoS ONE 10 (5) e0123301 [2015-05-20; online 2015-05-20]
Bioinformatics Short-term Support and Infrastructure (BILS)
PubMed DOI Crossref
CGGBP1 mitigates cytosine methylation at repetitive DNA sequences.
Agarwal P, Collier P, ..., Westermark B, Singh U
BMC Genomics 16 (-) 390 [2015-05-16; online 2015-05-16]
NGI Uppsala (Uppsala Genome Center)
PubMed DOI Crossref
Quantifying the impact of transporters on cellular drug permeability.
Matsson P, Fenu LA, ..., Kansy M, Artursson P
Trends Pharmacol. Sci. 36 (5) 255-262 [2015-05-00; online 2015-03-24]
ADME of Therapeutics (UDOPP)
PubMed DOI Crossref
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.
Coffee and Caffeine Genetics Consortium , Cornelis MC, ..., van Dam RM, Chasman DI
Mol. Psychiatry 20 (5) 647-656 [2015-05-00; online 2014-10-08]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Age- and sex-specific causal effects of adiposity on cardiovascular risk factors.
Fall T, Hägg S, ..., Ingelsson E, ENGAGE Consortium
Diabetes 64 (5) 1841-1852 [2015-05-00; online 2015-02-26]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Tracking the origin of metastatic prostate cancer.
Lindberg J, Kristiansen A, ..., Grönberg H, Egevad L
Eur. Urol. 67 (5) 819-822 [2015-05-00; online 2014-09-24]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)
PubMed
Diagnostic urinary proteome profile for immunoglobulin a nephropathy.
Samavat S, Kalantari S, ..., Parvin M, Zubarev RA
Iran J Kidney Dis 9 (3) 239-248 [2015-05-00; online 2015-05-10]
Advanced Mass Spectrometry Proteomics
PubMed DOI Crossref
Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery.
Mørch Ý, Hansen R, ..., de Lange Davies C, Stenstad PM
Contrast Media Mol Imaging 10 (5) 356-366 [2015-04-30; online 2015-04-30]
Advanced Light Microscopy
PubMed DOI Crossref
Genetically determined height and coronary artery disease.
Nelson CP, Hamby SE, ..., Samani NJ, CARDIoGRAM+C4D Consortium
N. Engl. J. Med. 372 (17) 1608-1618 [2015-04-23; online 2015-04-09]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Common genetic variants influence human subcortical brain structures.
Hibar DP, Stein JL, ..., Thompson PM, Medland SE
Nature 520 (7546) 224-229 [2015-04-09; online 2015-01-22]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Adiposity as a cause of cardiovascular disease: a Mendelian randomization study.
Hägg S, Fall T, ..., Ingelsson E, European Network for Genetic and Genomic Epidemiology Consortium
Int J Epidemiol 44 (2) 578-586 [2015-04-00; online 2015-05-27]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Fluctuating expression of microRNAs in adenovirus infected cells.
Zhao H, Chen M, Tellgren-Roth C, Pettersson U
Virology 478 (-) 99-111 [2015-04-00; online 2015-03-07]
NGI Uppsala (Uppsala Genome Center)
PubMed DOI Crossref
Methylation levels of SLC23A2 and NCOR2 genes correlate with spinal muscular atrophy severity.
Zheleznyakova GY, Nilsson EK, ..., Baranov VS, Schiöth HB
PLoS ONE 10 (3) e0121964 [2015-03-30; online 2015-03-30]
NGI Uppsala (Uppsala Genome Center)
PubMed DOI Crossref
Complete genome sequence of Borrelia afzelii K78 and comparative genome analysis.
Schüler W, Bunikis I, ..., Bergström S, Lundberg U
PLoS ONE 10 (3) e0120548 [2015-03-23; online 2015-03-23]
NGI Uppsala (Uppsala Genome Center)
PubMed DOI Crossref
SLC10A4 is a vesicular amine-associated transporter modulating dopamine homeostasis.
Larhammar M, Patra K, ..., Wallén-Mackenzie Å, Kullander K
Biol. Psychiatry 77 (6) 526-536 [2015-03-15; online 2014-09-02]
Advanced Light Microscopy
PubMed
Genomewide association study of body weight traits in Baluchi sheep.
Gholizadeh M, Rahimi-Mianji G, Nejati-Javaremi A
J. Genet. 94 (1) 143-146 [2015-03-00; online 2015-04-08]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Evolution of Darwin's finches and their beaks revealed by genome sequencing.
Lamichhaney S, Berglund J, ..., Webster MT, Andersson L
Nature 518 (7539) 371-375 [2015-02-19; online 2015-02-18]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Genetic studies of body mass index yield new insights for obesity biology.
Locke AE, Kahali B, ..., Loos RJ, Speliotes EK
Nature 518 (7538) 197-206 [2015-02-12; online 2015-02-13]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
New genetic loci link adipose and insulin biology to body fat distribution.
Shungin D, Winkler TW, ..., Lindgren CM, Mohlke KL
Nature 518 (7538) 187-196 [2015-02-12; online 2015-02-13]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
The composition of the gut microbiota shapes the colon mucus barrier.
Jakobsson HE, Rodríguez-Piñeiro AM, ..., Hansson GC, Johansson ME
EMBO Rep. 16 (2) 164-177 [2015-02-00; online 2014-12-20]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)
PubMed DOI Crossref
Variation in the human immune system is largely driven by non-heritable influences.
Brodin P, Jojic V, ..., Maecker HT, Davis MM
Cell 160 (1-2) 37-47 [2015-01-15; online 2015-01-17]
Mass Cytometry
PubMed DOI Crossref
Defects of CRB2 cause steroid-resistant nephrotic syndrome.
Ebarasi L, Ashraf S, ..., Hildebrandt F, Majumdar A
Am. J. Hum. Genet. 96 (1) 153-161 [2015-01-08; online 2015-01-06]
Zebrafish
PubMed DOI Crossref
A secretagogin locus of the mammalian hypothalamus controls stress hormone release.
Romanov RA, Alpár A, ..., Hökfelt T, Harkany T
EMBO J. 34 (1) 36-54 [2015-01-02; online 2014-11-29]
Fluorescence Tissue Profiling
PubMed DOI Crossref
Mutagenesis. Smoking is associated with mosaic loss of chromosome Y.
Dumanski JP, Rasi C, ..., Ingelsson E, Forsberg LA
Science 347 (6217) 81-83 [2015-01-02; online 2014-12-06]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Scavenging effect of Trolox released from brushite cements.
Mestres G, Santos CF, ..., Persson C, Ott MK
Acta Biomater 11 (-) 459-466 [2015-01-00; online 2014-09-18]
BioMaterial Interactions (BioMat)
PubMed DOI Crossref
The Biobanking Analysis Resource Catalogue (BARCdb): a new research tool for the analysis of biobank samples.
Galli J, Oelrich J, ..., Ortega-Paino E, Landegren U
Nucleic Acids Res. 43 (Database issue) D1158-D1162 [2015-01-00; online 2014-10-23]
PLA Proteomics