Immunity 43 (6) 1035-1037 [2015-12-15; online 2015-12-20]
In this issue of Immunity, Andres-Terre et al. (2015) and Nakaya et al. (2015) perform multi-cohort meta-analyses of immune responses to viruses and vaccines. With increased statistical power and more diverse sampling populations, their findings promise to be more generally applicable and suggestive of novel mechanisms for regulating immunity.