Bioorg. Med. Chem.

A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens.

Vella P, Rudraraju RS, Lundbäck T, ..., Schneider G, Schnell R

Bioorg. Med. Chem. 30 (-) 115898 [2021-01-15; online 2020-12-05]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands.

Wannberg J, Gising J, Lindman J, ..., Hallberg M, Larhed M

Bioorg. Med. Chem. 29 (-) 115859 [2021-01-01; online 2020-11-07]

Drug Discovery and Development (DDD) [Collaborative]

Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB).

De Rosa M, Lu L, Zamaratski E, ..., Mowbray SL, Karlén A

Bioorg. Med. Chem. 25 (3) 897-911 [2017-02-01; online 2016-12-07]

Spatial Mass Spectrometry [Service]

Vinylated linear P2 pyrimidinyloxyphenylglycine based inhibitors of the HCV NS3/4A protease and corresponding macrocycles.

Lampa A, Alogheli H, Ehrenberg AE, ..., Karlén A, Sandström A

Bioorg. Med. Chem. 22 (23) 6595-6615 [2014-12-01; online 2014-12-03]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]