Publications 2011

164 publications

PubMed DOI Crossref
Muscle wasting and the temporal gene expression pattern in a novel rat intensive care unit model.
Llano-Diez M, Gustafson AM, Olsson C, Goransson H, Larsson L
pmc
BMC Genomics 12 (-) 602 [2011-12-13; online 2011-12-13]
Array and Analysis Facility
PubMed DOI Crossref
Blood pressure loci identified with a gene-centric array.
Johnson T, Gaunt TR, Newhouse SJ, ..., Caulfield MJ, Munroe PB
pmc
Am. J. Hum. Genet. 89 (6) 688-700 [2011-12-09; online 2011-11-22]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers.
Cox DG, Simard J, Sinnett D, ..., Sinilnikova OM, Consortium of Investigators of Modifiers of BRCA1/2
pmc
Hum. Mol. Genet. 20 (23) 4732-4747 [2011-12-01; online 2011-09-06]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)
PubMed DOI Crossref
High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer.
Hjelm B, Brennan DJ, Zendehrokh N, ..., Jirström K, Uhlen M
Proteomics Clin Appl 5 (11-12) 624-635 [2011-12-00; online 2011-10-01]
Tissue Profiling
PubMed DOI Crossref
Counting absolute numbers of molecules using unique molecular identifiers.
Kivioja T, Vähärautio A, Karlsson K, ..., Linnarsson S, Taipale J
Nat. Methods 9 (1) 72-74 [2011-11-20; online 2011-11-20]
Karolinska High Throughput Center (KHTC)
PubMed DOI Crossref
A lateral flow protein microarray for rapid and sensitive antibody assays.
Gantelius J, Bass T, Sjöberg R, Nilsson P, Andersson-Svahn H
pmc
Int J Mol Sci 12 (11) 7748-7759 [2011-11-09; online 2011-11-09]
PubMed DOI Crossref
Inhibition of proteasome deubiquitinating activity as a new cancer therapy.
D'Arcy P, Brnjic S, Olofsson MH, ..., Larsson R, Linder S
GEO
Nat. Med. 17 (12) 1636-1640 [2011-11-06; online 2011-11-06]
Array and Analysis Facility
PubMed DOI Crossref
Plasma profiling reveals human fibulin-1 as candidate marker for renal impairment.
Neiman M, Hedberg JJ, Dönnes PR, ..., Schwenk JM, Nilsson P
J. Proteome Res. 10 (11) 4925-4934 [2011-11-04; online 2011-09-29]
Plasma Profiling [Collaborative]
PubMed DOI Crossref
Abundant class of non-coding RNA regulates development in the social amoeba Dictyostelium discoideum.
Avesson L, Schumacher HT, Fechter P, ..., Hellman U, Söderbom F
RNA Biol 8 (6) 1094-1104 [2011-11-01; online 2011-09-24]
NGI Uppsala (Uppsala Genome Center)
PubMed DOI Crossref
Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse.
Lindfors C, Nilsson IA, Garcia-Roves PM, ..., Schalling M, Johansen JE
pmc
Proc. Natl. Acad. Sci. U.S.A. 108 (44) 18108-18113 [2011-11-01; online 2011-10-26]
Fluorescence Tissue Profiling
PubMed DOI Crossref
Western blotting via proximity ligation for high performance protein analysis.
Liu Y, Gu J, Hagner-McWhirter Å, ..., Ivansson D, Landegren U
pmc
Mol. Cell Proteomics 10 (11) O111.011031 [2011-11-00; online 2011-08-05]
PLA Proteomics
PubMed DOI Crossref
Increasing the dynamic range of in situ PLA.
Clausson C, Allalou A, Weibrecht I, ..., Wählby C, Söderberg O
Nat. Methods 8 (11) 892-893 [2011-10-28; online 2011-10-28]
BioImage Informatics [Collaborative] PLA Proteomics
PubMed DOI Crossref
Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity.
Rasmussen M, Sundström M, Göransson Kultima H, ..., Glimelius B, Isaksson A
pmc
Genome Biol. 12 (10) R108 [2011-10-24; online 2011-10-24]
Array and Analysis Facility
PubMed DOI Crossref
MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas.
Mäkinen N, Mehine M, Tolvanen J, ..., Vahteristo P, Aaltonen LA
GEO
Science 334 (6053) 252-255 [2011-10-14; online 2011-08-27]
Karolinska High Throughput Center (KHTC)
PubMed DOI Crossref
Histone modifications influence mediator interactions with chromatin.
Zhu X, Zhang Y, Bjornsdottir G, ..., Gustafsson CM, Myers LC
pmc
Nucleic Acids Res. 39 (19) 8342-8354 [2011-10-00; online 2011-07-12]
Bioinformatics and Expression Analysis (BEA)
PubMed DOI Crossref
The Lin28/let-7 axis regulates glucose metabolism.
Zhu H, Shyh-Chang N, Segrè AV, ..., Altshuler D, Daley GQ
pmc mid
Cell 147 (1) 81-94 [2011-09-30; online 2011-10-04]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing.
Darmanis S, Nong RY, Vänelid J, ..., Kamali-Moghaddam M, Landegren U
pmc
PLoS ONE 6 (9) e25583 [2011-09-29; online 2011-09-29]
PLA Proteomics
PubMed DOI Crossref
Large-scale protein profiling in human cell lines using antibody-based proteomics.
Fagerberg L, Strömberg S, El-Obeid A, ..., Ponten F, Asplund A
J. Proteome Res. 10 (9) 4066-4075 [2011-09-02; online 2011-07-06]
Tissue Profiling
PubMed DOI Crossref
Variants in STAT5B associate with serum TC and LDL-C levels.
Kornfeld JW, Isaacs A, Vitart V, ..., Pramstaller PP, Hicks AA
J. Clin. Endocrinol. Metab. 96 (9) E1496-E1501 [2011-09-00; online 2011-07-15]
NGI Uppsala (Uppsala Genome Center)
PubMed DOI Crossref
Combinations of SNPs related to signal transduction in bipolar disorder.
Koefoed P, Andreassen OA, Bennike B, ..., Werge T, Mellerup E
pmc
PLoS ONE 6 (8) e23812 [2011-08-29; online 2011-08-29]
NGI Uppsala (SNP&SEQ Technology Platform) [Service]
PubMed DOI Crossref
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
International Multiple Sclerosis Genetics Consortium , Wellcome Trust Case Control Consortium 2 , Sawcer S, ..., Donnelly P, Compston A
pmc mid
Nature 476 (7359) 214-219 [2011-08-10; online 2011-08-10]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Functional and prognostic relevance of the homeobox protein MSX2 in malignant melanoma.
Gremel G, Ryan D, Rafferty M, ..., Ponten F, Gallagher WM
pmc
Br. J. Cancer 105 (4) 565-574 [2011-08-09; online 2011-07-07]
Tissue Profiling
PubMed DOI Crossref
Mapping the subcellular protein distribution in three human cell lines.
Fagerberg L, Stadler C, Skogs M, ..., Uhlén M, Lundberg E
J. Proteome Res. 10 (8) 3766-3777 [2011-08-05; online 2011-06-17]
Cell Profiling
PubMed DOI Crossref
The genetic structure of the Swedish population.
Humphreys K, Grankvist A, Leu M, ..., Palmgren J, Magnusson PK
pmc
PLoS ONE 6 (8) e22547 [2011-08-04; online 2011-08-04]
NGI Uppsala (SNP&SEQ Technology Platform) [Service]
PubMed DOI Crossref
Influence of the COMT genotype on working memory and brain activity changes during development.
Dumontheil I, Roggeman C, Ziermans T, ..., Kere J, Klingberg T
Biol. Psychiatry 70 (3) 222-229 [2011-08-01; online 2011-04-26]
Mutation Analysis Facility (MAF)
PubMed
RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer.
Ehlén Å, Nodin B, Rexhepaj E, ..., Brennan DJ, Jirström K
pmc
Transl Oncol 4 (4) 212-221 [2011-08-00; online 2011-08-01]
Tissue Profiling
PubMed DOI Crossref
Potential association of muscarinic receptor 3 gene variants with primary Sjogren's syndrome.
Appel S, Le Hellard S, Bruland O, ..., Wahren-Herlenius M, Jonsson R
Ann. Rheum. Dis. 70 (7) 1327-1329 [2011-07-00; online 2011-04-01]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Genetic architecture of circulating lipid levels.
Demirkan A, Amin N, Isaacs A, ..., van Duijn CM, ENGAGE CONSORTIUM
pmc
Eur. J. Hum. Genet. 19 (7) 813-819 [2011-07-00; online 2011-03-30]
NGI Uppsala (SNP&SEQ Technology Platform) [Service]
PubMed DOI Crossref
SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas.
Magnusson K, de Wit M, Brennan DJ, ..., Jirström K, Pontén F
Am. J. Surg. Pathol. 35 (7) 937-948 [2011-07-00; online 2011-06-17]
Cell Profiling Tissue Profiling
PubMed DOI Crossref
Concomitant autoimmunity in myasthenia gravis--lack of association with IgA deficiency.
Ramanujam R, Piehl F, Pirskanen R, Gregersen PK, Hammarström L
pmc mid
J. Neuroimmunol. 236 (1-2) 118-122 [2011-07-00; online 2011-06-15]
Mutation Analysis Facility (MAF)
PubMed DOI Crossref
Prostasomal DNA characterization and transfer into human sperm.
Ronquist GK, Larsson A, Ronquist G, ..., Carlsson L, Stavreus-Evers A
Mol. Reprod. Dev. 78 (7) 467-476 [2011-07-00; online 2011-06-04]
Array and Analysis Facility
PubMed DOI Crossref
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.
Kilpeläinen TO, Zillikens MC, Stančákova A, ..., Laakso M, Loos RJ
pmc mid
Nat. Genet. 43 (8) 753-760 [2011-06-26; online 2011-06-26]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
KIT pathway alterations in mucosal melanomas of the vulva and other sites.
Omholt K, Grafström E, Kanter-Lewensohn L, Hansson J, Ragnarsson-Olding BK
Clin. Cancer Res. 17 (12) 3933-3942 [2011-06-15; online 2011-06-18]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)
PubMed DOI Crossref
The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men.
Benedict C, Jacobsson JA, Rönnemaa E, ..., Kilander L, Schiöth HB
Neurobiol. Aging 32 (6) 1159.e1-1159.e5 [2011-06-00; online 2011-04-05]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer.
Tavoosidana G, Ronquist G, Darmanis S, ..., Landegren UD, Kamali-Moghaddam M
pmc
Proc. Natl. Acad. Sci. U.S.A. 108 (21) 8809-8814 [2011-05-24; online 2011-05-11]
Clinical Biomarkers PLA Proteomics
PubMed DOI Crossref
Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer.
Wallin U, Glimelius B, Jirström K, ..., Påhlman L, Birgisson H
pmc
Br. J. Cancer 104 (10) 1619-1627 [2011-05-10; online 2011-04-07]
Tissue Profiling
PubMed DOI Crossref
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
Jakobsen L, Vanselow K, Skogs M, ..., Hyman AA, Andersen JS
pmc
EMBO J. 30 (8) 1520-1535 [2011-04-20; online 2011-03-15]
Cell Profiling
PubMed DOI Crossref
Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: an association study.
Holtze M, Saetre P, Erhardt S, ..., Jönsson EG, Schalling M
Schizophr. Res. 127 (1-3) 270-272 [2011-04-00; online 2010-10-30]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Utilizing twins concordance rates to infer the predisposition to myasthenia gravis.
Ramanujam R, Pirskanen R, Ramanujam S, Hammarström L
Twin Res Hum Genet 14 (2) 129-136 [2011-04-00; online 2011-03-24]
Mutation Analysis Facility (MAF)
PubMed DOI Crossref
Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP).
Hashemi J, Worrall C, Vasilcanu D, ..., Larsson O, Larsson C
pmc
PLoS ONE 6 (3) e14757 [2011-03-14; online 2011-03-14]
Mutation Analysis Facility (MAF)
PubMed DOI Crossref
Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome.
Nordmark G, Kristjansdottir G, Theander E, ..., Jonsson R, Syvänen AC
Genes Immun. 12 (2) 100-109 [2011-03-00; online 2010-09-24]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.
Ameur A, Stewart JB, Freyer C, ..., Larsson N, Gyllensten U
pmc
PLoS Genet. 7 (3) e1002028 [2011-03-00; online 2011-03-24]
NGI Uppsala (Uppsala Genome Center)
PubMed DOI Crossref
CUBN is a gene locus for albuminuria.
Böger CA, Chen MH, Tin A, ..., Fox CS, Kao WH
pmc
J. Am. Soc. Nephrol. 22 (3) 555-570 [2011-03-00; online 2011-03-01]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Genetic association of sequence variants near AGER/NOTCH4 and dementia.
Bennet AM, Reynolds CA, Eriksson UK, ..., Pedersen NL, Prince JA
pmc mid
J. Alzheimers Dis. 24 (3) 475-484 [2011-02-08; online 2011-02-08]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Diagnostic biomarkers of prostate cancer.
Häggarth L, Hägglöf C, Jaraj SJ, ..., Ostman A, Egevad L
Scand. J. Urol. Nephrol. 45 (1) 60-67 [2011-02-00; online 2010-11-03]
Tissue Profiling
PubMed DOI Crossref
GAD1 is a biomarker for benign and malignant prostatic tissue.
Jaraj SJ, Augsten M, Häggarth L, ..., Ostman A, Egevad L
Scand. J. Urol. Nephrol. 45 (1) 39-45 [2011-02-00; online 2010-11-26]
Tissue Profiling
PubMed DOI Crossref
Fine mapping and replication of QTL in outbred chicken advanced intercross lines.
Besnier F, Wahlberg P, Rönnegård L, ..., Siegel PB, Carlborg O
pmc
Genet. Sel. Evol. 43 (1) 3 [2011-01-17; online 2011-01-17]
NGI Uppsala (SNP&SEQ Technology Platform)
PubMed DOI Crossref
Vitamin D receptor genotypes, ultraviolet radiation exposure, and risk of non-Hodgkin lymphoma.
Smedby KE, Eloranta S, Duvefelt K, ..., Hjalgrim H, Chang ET
Am. J. Epidemiol. 173 (1) 48-54 [2011-01-01; online 2010-11-16]
Mutation Analysis Facility (MAF)
PubMed DOI Crossref
Mechanisms of blast induced brain injuries, experimental studies in rats.
Risling M, Plantman S, Angeria M, ..., Arborelius U, Davidsson J
Neuroimage 54 Suppl 1 (-) S89-S97 [2011-01-00; online 2010-05-25]
Bioinformatics and Expression Analysis (BEA)
PubMed DOI Crossref
Meta-analysis of the association between variants in SORL1 and Alzheimer disease.
Reitz C, Cheng R, Rogaeva E, ..., Mayeux R, Genetic and Environmental Risk in Alzheimer Disease 1 Consortium
pmc mid
Arch. Neurol. 68 (1) 99-106 [2011-01-00; online 2011-01-12]
NGI Uppsala (SNP&SEQ Technology Platform)