Publications 2011

Mechanisms underlying the sparing of masticatory versus limb muscle function in an experimental critical illness model.

Aare S, Ochala J, Norman HS, ..., Hoffman EP, Larsson L

Physiol. Genomics 43 (24) 1334-1350 [2011-12-16; online 2011-10-20]

Association between body mass index and insulin receptor substrate-4 (IRS-4) gene polymorphisms in patients with schizophrenia.

Melkersson K, Persson B

Neuro Endocrinol. Lett. 32 (5) 634-640 [2011-12-15; online 2011-12-15]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Identification of immunogenic proteins in Treponema phagedenis-like strain V1 from digital dermatitis lesions by phage display.

Rosander A, Guss B, Frykberg L, ..., Näslund K, Pringle M

Vet. Microbiol. 153 (3-4) 315-322 [2011-12-15; online 2011-07-19]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.

Huffman JE, Knezevic A, Vitart V, ..., Wright AF, Lauc G

Hum. Mol. Genet. 20 (24) 5000-5011 [2011-12-15; online 2011-09-13]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

The inner nuclear membrane proteins Man1 and Ima1 link to two different types of chromatin at the nuclear periphery in S. pombe.

Steglich B, Filion GJ, van Steensel B, Ekwall K

Nucleus 3 (1) 77-87 [2011-12-14; online 2011-12-14]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Muscle wasting and the temporal gene expression pattern in a novel rat intensive care unit model.

Llano-Diez M, Gustafson AM, Olsson C, Goransson H, Larsson L

pmc

BMC Genomics 12 (-) 602 [2011-12-13; online 2011-12-13]

Array and Analysis Facility

PubMed DOI Crossref

Blood pressure loci identified with a gene-centric array.

Johnson T, Gaunt TR, Newhouse SJ, ..., Caulfield MJ, Munroe PB

pmc

Am. J. Hum. Genet. 89 (6) 688-700 [2011-12-09; online 2011-11-22]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers.

Cox DG, Simard J, Sinnett D, ..., Sinilnikova OM, Consortium of Investigators of Modifiers of BRCA1/2

pmc

Hum. Mol. Genet. 20 (23) 4732-4747 [2011-12-01; online 2011-09-06]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Pathway-based analysis of genetic susceptibility to cervical cancer in situ: HLA-DPB1 affects risk in Swedish women.

Ivansson EL, Juko-Pecirep I, Erlich HA, Gyllensten UB

Genes Immun. 12 (8) 605-614 [2011-12-00; online 2011-07-01]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Salt-inducible kinase 1 influences Na(+),K(+)-ATPase activity in vascular smooth muscle cells and associates with variations in blood pressure.

Popov S, Silveira A, Wågsäter D, ..., Melander O, Bertorello AM

J. Hypertens. 29 (12) 2395-2403 [2011-12-00; online 2011-11-03]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer.

Hjelm B, Brennan DJ, Zendehrokh N, ..., Jirström K, Uhlen M

Proteomics Clin Appl 5 (11-12) 624-635 [2011-12-00; online 2011-10-01]

Tissue Profiling

PubMed DOI Crossref

A complex genomic rearrangement involving the endothelin 3 locus causes dermal hyperpigmentation in the chicken.

Dorshorst B, Molin A, Rubin C, ..., Ashwell C, Andersson L

pmc

PLoS Genet. 7 (12) e1002412 [2011-12-00; online 2011-12-22]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Targeting acetylcholinesterase: identification of chemical leads by high throughput screening, structure determination and molecular modeling.

Berg L, Andersson CD, Artursson E, ..., Linusson A, Ekström F

pmc

PLoS ONE 6 (11) e26039 [2011-11-30; online 2011-11-30]

Chemical Biology Consortium Sweden (CBCS) [Service]

PubMed DOI Crossref

Next-generation sequencing technologies and applications for human genetic history and forensics.

Berglund EC, Kiialainen A, Syvänen AC

pmc

Investig Genet 2 (-) 23 [2011-11-24; online 2011-11-24]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Counting absolute numbers of molecules using unique molecular identifiers.

Kivioja T, Vähärautio A, Karlsson K, ..., Linnarsson S, Taipale J

Nat. Methods 9 (1) 72-74 [2011-11-20; online 2011-11-20]

Karolinska High Throughput Center (KHTC)

PubMed DOI Crossref

Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks.

Deneberg S, Guardiola P, Lennartsson A, ..., Döhner K, Lehmann S

Blood 118 (20) 5573-5582 [2011-11-17; online 2011-10-01]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model.

Kato BS, Nicholson G, Neiman M, ..., Spector TD, Schwenk JM

pmc

Proteome Sci 9 (-) 73 [2011-11-17; online 2011-11-17]

Plasma Profiling [Collaborative]

PubMed DOI Crossref

Genome sequencing reveals a phage in Helicobacter pylori.

Lehours P, Vale FF, Bjursell MK, ..., Engstrand L, Andersson AF

MBio 2 (6) - [2011-11-15; online 2011-11-15]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1.

Bown MJ, Jones GT, Harrison SC, ..., Deloukas P, Samani NJ

pmc

Am. J. Hum. Genet. 89 (5) 619-627 [2011-11-11; online 2011-11-08]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

A lateral flow protein microarray for rapid and sensitive antibody assays.

Gantelius J, Bass T, Sjöberg R, Nilsson P, Andersson-Svahn H

pmc

Int J Mol Sci 12 (11) 7748-7759 [2011-11-09; online 2011-11-09]

PubMed DOI Crossref

Inhibition of proteasome deubiquitinating activity as a new cancer therapy.

D'Arcy P, Brnjic S, Olofsson MH, ..., Larsson R, Linder S

GEO

Nat. Med. 17 (12) 1636-1640 [2011-11-06; online 2011-11-06]

Array and Analysis Facility

PubMed DOI Crossref

Total RNA sequencing reveals nascent transcription and widespread co-transcriptional splicing in the human brain.

Ameur A, Zaghlool A, Halvardson J, ..., Cavelier L, Feuk L

Nat. Struct. Mol. Biol. 18 (12) 1435-1440 [2011-11-06; online 2011-11-06]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Plasma profiling reveals human fibulin-1 as candidate marker for renal impairment.

Neiman M, Hedberg JJ, Dönnes PR, ..., Schwenk JM, Nilsson P

J. Proteome Res. 10 (11) 4925-4934 [2011-11-04; online 2011-09-29]

Plasma Profiling [Collaborative]

PubMed DOI Crossref

SWI/SNF regulates the alternative processing of a specific subset of pre-mRNAs in Drosophila melanogaster.

Waldholm J, Wang Z, Brodin D, ..., Farrants AK, Visa N

pmc

BMC Mol. Biol. 12 (-) 46 [2011-11-02; online 2011-11-02]

Bioinformatics and Expression Analysis (BEA)

PubMed DOI Crossref

Abundant class of non-coding RNA regulates development in the social amoeba Dictyostelium discoideum.

Avesson L, Schumacher HT, Fechter P, ..., Hellman U, Söderbom F

RNA Biol 8 (6) 1094-1104 [2011-11-01; online 2011-09-24]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse.

Lindfors C, Nilsson IA, Garcia-Roves PM, ..., Schalling M, Johansen JE

pmc

Proc. Natl. Acad. Sci. U.S.A. 108 (44) 18108-18113 [2011-11-01; online 2011-10-26]

Fluorescence Tissue Profiling

PubMed DOI Crossref

Targeted enrichment of genomic DNA regions for next-generation sequencing.

Mertes F, Elsharawy A, Sauer S, ..., Lehrach H, Brookes AJ

pmc

Brief Funct Genomics 10 (6) 374-386 [2011-11-00; online 2011-11-26]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Gene copy number aberrations are associated with survival in histologic subgroups of non-small cell lung cancer.

Micke P, Edlund K, Holmberg L, ..., Isaksson A, Botling J

J Thorac Oncol 6 (11) 1833-1840 [2011-11-00; online 2011-10-21]

Array and Analysis Facility

PubMed DOI Crossref

The Human Protein Atlas as a proteomic resource for biomarker discovery.

Pontén F, Schwenk JM, Asplund A, Edqvist PD

J. Intern. Med. 270 (5) 428-446 [2011-11-00; online 2011-07-15]

Plasma Profiling [Technology development] Tissue Profiling

PubMed DOI Crossref

Western blotting via proximity ligation for high performance protein analysis.

Liu Y, Gu J, Hagner-McWhirter Å, ..., Ivansson D, Landegren U

pmc

Mol. Cell Proteomics 10 (11) O111.011031 [2011-11-00; online 2011-08-05]

PLA and Single Cell Proteomics

PubMed DOI Crossref

Generation of monospecific antibodies based on affinity capture of polyclonal antibodies.

Hjelm B, Forsström B, Igel U, ..., Johansson C, Uhlén M

pmc

Protein Sci. 20 (11) 1824-1835 [2011-11-00; online 2011-09-08]

Autoimmunity Profiling [Technology development] Cell Profiling Plasma Profiling [Technology development]

PubMed DOI Crossref

Increasing the dynamic range of in situ PLA.

Clausson C, Allalou A, Weibrecht I, ..., Wählby C, Söderberg O

Nat. Methods 8 (11) 892-893 [2011-10-28; online 2011-10-28]

BioImage Informatics [Collaborative] PLA and Single Cell Proteomics

PubMed DOI Crossref

Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity.

Rasmussen M, Sundström M, Göransson Kultima H, ..., Glimelius B, Isaksson A

pmc

Genome Biol. 12 (10) R108 [2011-10-24; online 2011-10-24]

Array and Analysis Facility

PubMed DOI Crossref

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.

Chambers JC, Zhang W, Sehmi J, ..., Elliott P, Kooner JS

pmc mid

Nat. Genet. 43 (11) 1131-1138 [2011-10-16; online 2011-10-16]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas.

Mäkinen N, Mehine M, Tolvanen J, ..., Vahteristo P, Aaltonen LA

GEO

Science 334 (6053) 252-255 [2011-10-14; online 2011-08-27]

Karolinska High Throughput Center (KHTC)

PubMed DOI Crossref

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.

Rivas MA, Beaudoin M, Gardet A, ..., Xavier RJ, Daly MJ

pmc mid

Nat. Genet. 43 (11) 1066-1073 [2011-10-09; online 2011-10-09]

Mutation Analysis Facility (MAF)

PubMed DOI Crossref

Pseudoceramines A-D, new antibacterial bromotyrosine alkaloids from the marine sponge Pseudoceratina sp.

Yin S, Davis RA, Shelper T, ..., Sundin C, Quinn RJ

Org. Biomol. Chem. 9 (19) 6755-6760 [2011-10-07; online 2011-08-19]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

PubMed DOI Crossref

Adenosine kinase deficiency disrupts the methionine cycle and causes hypermethioninemia, encephalopathy, and abnormal liver function.

Bjursell MK, Blom HJ, Cayuela JA, ..., Lundeberg J, Wedell A

pmc

Am. J. Hum. Genet. 89 (4) 507-515 [2011-10-07; online 2011-10-04]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Genetic variation in complement component C3 shows association with ischaemic stroke.

Olsson S, Stokowska A, Holmegaard L, ..., Pekna M, Jern C

Eur. J. Neurol. 18 (10) 1272-1274 [2011-10-00; online 2011-03-19]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Evidence for involvement of Dicer-like, Argonaute and histone deacetylase proteins in gene silencing in Phytophthora infestans.

Vetukuri RR, Avrova AO, Grenville-Briggs LJ, ..., Whisson SC, Dixelius C

Mol. Plant Pathol. 12 (8) 772-785 [2011-10-00; online 2011-07-06]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

DOI Crossref

Tracking Phytophthora infestans with SSR markers within and between seasons - a field study in Sweden

Widmark AK, Andersson B, Sandström M, Yuen JE

Plant Pathol 60 (5) 938-945 [2011-10-00; online 2011-03-16]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

No evidence for an association between genetic variation at the SERPINI1 locus and ischemic stroke.

Tjärnlund-Wolf A, Olsson S, Jood K, Blomstrand C, Jern C

J. Neurol. 258 (10) 1885-1887 [2011-10-00; online 2011-04-14]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Early transcriptional regulation by C-peptide in freshly isolated rat proximal tubular cells.

Lindahl E, Nordquist L, Müller P, ..., Palm F, Jörnvall H

Diabetes Metab. Res. Rev. 27 (7) 697-704 [2011-10-00; online 2011-05-28]

Bioinformatics and Expression Analysis (BEA)

PubMed DOI Crossref

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.

Strawbridge RJ, Dupuis J, Prokopenko I, ..., Hamsten A, Florez JC

pmc

Diabetes 60 (10) 2624-2634 [2011-10-00; online 2011-08-30]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

High-risk HPV infection and CIN grade correlates to the expression of c-myc, CD4+, FHIT, E-cadherin, Ki-67, and p16INK4a.

Samir R, Asplund A, Tot T, Pekar G, Hellberg D

J Low Genit Tract Dis 15 (4) 280-286 [2011-10-00; online 2011-05-12]

Tissue Profiling

PubMed DOI Crossref

Histone modifications influence mediator interactions with chromatin.

Zhu X, Zhang Y, Bjornsdottir G, ..., Gustafsson CM, Myers LC

pmc

Nucleic Acids Res. 39 (19) 8342-8354 [2011-10-00; online 2011-07-12]

Bioinformatics and Expression Analysis (BEA)

PubMed DOI Crossref

The Lin28/let-7 axis regulates glucose metabolism.

Zhu H, Shyh-Chang N, Segrè AV, ..., Altshuler D, Daley GQ

pmc mid

Cell 147 (1) 81-94 [2011-09-30; online 2011-10-04]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing.

Darmanis S, Nong RY, Vänelid J, ..., Kamali-Moghaddam M, Landegren U

pmc

PLoS ONE 6 (9) e25583 [2011-09-29; online 2011-09-29]

PLA and Single Cell Proteomics

PubMed DOI Crossref

High RBM3 expression in prostate cancer independently predicts a reduced risk of biochemical recurrence and disease progression.

Jonsson L, Gaber A, Ulmert D, ..., Bjartell A, Jirström K

pmc

Diagn Pathol 6 (-) 91 [2011-09-28; online 2011-09-28]

Tissue Profiling

PubMed DOI Crossref

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.

Wain LV, Verwoert GC, O'Reilly PF, ..., Elliott P, van Duijn CM

pmc mid

Nat. Genet. 43 (10) 1005-1011 [2011-09-11; online 2011-09-11]

NGI Uppsala (SNP&SEQ Technology Platform) [Service]

PubMed DOI Crossref

Engineering GST M2-2 for high activity with indene 1,2-oxide and indication of an H-site residue sustaining catalytic promiscuity.

Norrgård MA, Mannervik B

J. Mol. Biol. 412 (1) 111-120 [2011-09-09; online 2011-08-09]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Large-scale protein profiling in human cell lines using antibody-based proteomics.

Fagerberg L, Strömberg S, El-Obeid A, ..., Ponten F, Asplund A

J. Proteome Res. 10 (9) 4066-4075 [2011-09-02; online 2011-07-06]

Tissue Profiling

PubMed DOI Crossref

Transcriptional profiling of C. elegans DAF-19 uncovers a ciliary base-associated protein and a CDK/CCRK/LF2p-related kinase required for intraflagellar transport.

Phirke P, Efimenko E, Mohan S, ..., Leroux MR, Swoboda P

pmc mid

Dev. Biol. 357 (1) 235-247 [2011-09-01; online 2011-07-12]

Bioinformatics and Expression Analysis (BEA)

PubMed DOI Crossref

Genomic and clinical characteristics of six patients with partially overlapping interstitial deletions at 10p12p11.

Wentzel C, Rajcan-Separovic E, Ruivenkamp CA, ..., Giurgea I, Thuresson AC

pmc

Eur. J. Hum. Genet. 19 (9) 959-964 [2011-09-00; online 2011-04-28]

Array and Analysis Facility NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers.

Andreou D, Saetre P, Kähler AK, ..., Terenius L, Jönsson EG

Eur Neuropsychopharmacol 21 (9) 700-704 [2011-09-00; online 2011-02-08]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Variants in STAT5B associate with serum TC and LDL-C levels.

Kornfeld JW, Isaacs A, Vitart V, ..., Pramstaller PP, Hicks AA

J. Clin. Endocrinol. Metab. 96 (9) E1496-E1501 [2011-09-00; online 2011-07-15]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Structural features determining the intestinal epithelial permeability and efflux of novel HIV-1 protease inhibitors.

Lazorova L, Hubatsch I, Ekegren JK, ..., Larhed M, Artursson P

pmc

J Pharm Sci 100 (9) 3763-3772 [2011-09-00; online 2011-04-15]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

PubMed DOI Crossref

Large-scale gene-centric analysis identifies novel variants for coronary artery disease.

IBC 50K CAD Consortium N

pmc

PLoS Genet. 7 (9) e1002260 [2011-09-00; online 2011-09-22]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis.

Kanoni S, Nettleton JA, Hivert MF, ..., Franks PW, Dedoussis GV

pmc

Diabetes 60 (9) 2407-2416 [2011-09-00; online 2011-08-04]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Combinations of SNPs related to signal transduction in bipolar disorder.

Koefoed P, Andreassen OA, Bennike B, ..., Werge T, Mellerup E

pmc

PLoS ONE 6 (8) e23812 [2011-08-29; online 2011-08-29]

NGI Uppsala (SNP&SEQ Technology Platform) [Service]

PubMed DOI Crossref

Identification of Bacterial Target Proteins for the Salicylidene Acylhydrazide Class of Virulence-blocking Compounds

Wang D, Zetterström CE, Gabrielsen M, ..., Elofsson M, Roe AJ

J. Biol. Chem. 286 (34) 29922-29931 [2011-08-26; online 2011-07-01]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

PubMed DOI Crossref

Changes in the acetogenic population in a mesophilic anaerobic digester in response to increasing ammonia concentration.

Westerholm M, Müller B, Arthurson V, Schnürer A

GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK

Microbes Environ. 26 (4) 347-353 [2011-08-24; online 2011-08-24]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels.

Debette S, Visvikis-Siest S, Chen MH, ..., Vasan RS, Seshadri S

pmc mid

Circ. Res. 109 (5) 554-563 [2011-08-19; online 2011-07-16]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Characterization of a 8q21.11 microdeletion syndrome associated with intellectual disability and a recognizable phenotype.

Palomares M, Delicado A, Mansilla E, ..., Hennekam RC, Lapunzina P

pmc

Am. J. Hum. Genet. 89 (2) 295-301 [2011-08-12; online 2011-08-02]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

International Multiple Sclerosis Genetics Consortium , Wellcome Trust Case Control Consortium 2 , Sawcer S, ..., Donnelly P, Compston A

pmc mid

Nature 476 (7359) 214-219 [2011-08-10; online 2011-08-10]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Functional and prognostic relevance of the homeobox protein MSX2 in malignant melanoma.

Gremel G, Ryan D, Rafferty M, ..., Ponten F, Gallagher WM

pmc

Br. J. Cancer 105 (4) 565-574 [2011-08-09; online 2011-07-07]

Tissue Profiling

PubMed DOI Crossref

Mapping the subcellular protein distribution in three human cell lines.

Fagerberg L, Stadler C, Skogs M, ..., Uhlén M, Lundberg E

J. Proteome Res. 10 (8) 3766-3777 [2011-08-05; online 2011-06-17]

Cell Profiling

PubMed DOI Crossref

Complete genome sequence of Brachyspira intermedia reveals unique genomic features in Brachyspira species and phage-mediated horizontal gene transfer.

Håfström T, Jansson DS, Segerman B

pmc

BMC Genomics 12 (-) 395 [2011-08-04; online 2011-08-04]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

The genetic structure of the Swedish population.

Humphreys K, Grankvist A, Leu M, ..., Palmgren J, Magnusson PK

pmc

PLoS ONE 6 (8) e22547 [2011-08-04; online 2011-08-04]

NGI Uppsala (SNP&SEQ Technology Platform) [Service]

PubMed DOI Crossref

Influence of the COMT genotype on working memory and brain activity changes during development.

Dumontheil I, Roggeman C, Ziermans T, ..., Kere J, Klingberg T

Biol. Psychiatry 70 (3) 222-229 [2011-08-01; online 2011-04-26]

Mutation Analysis Facility (MAF)

PubMed DOI Crossref

Evaluation of Fanconi anaemia genes FANCA, FANCC and FANCL in cervical cancer susceptibility.

Juko-Pecirep I, Ivansson EL, Gyllensten UB

Gynecol. Oncol. 122 (2) 377-381 [2011-08-00; online 2011-05-06]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia.

Gunnarsson R, Mansouri L, Isaksson A, ..., Juliusson G, Rosenquist R

pmc

Haematologica 96 (8) 1161-1169 [2011-08-00; online 2011-05-07]

Array and Analysis Facility NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Lack of association between two dopamine D2 receptor gene polymorphisms and schizophrenia.

Caprini S, Saetre P, Melle I, ..., Terenius L, Jönsson EG

Psychiatr. Genet. 21 (4) 214-215 [2011-08-00; online 2011-06-30]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Gene-environment interactions between CRHR1 variants and physical assault in suicide attempts.

Ben-Efraim YJ, Wasserman D, Wasserman J, Sokolowski M

Genes Brain Behav. 10 (6) 663-672 [2011-08-00; online 2011-05-25]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Hyphae-colonizing Burkholderia sp.--a new source of biological control agents against sheath blight disease (Rhizoctonia solani AG1-IA) in rice.

Cuong ND, Nicolaisen MH, Sørensen J, Olsson S

Microb. Ecol. 62 (2) 425-434 [2011-08-00; online 2011-03-03]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

The short non-coding transcriptome of the protozoan parasite Trypanosoma cruzi.

Franzén O, Arner E, Ferella M, ..., Andersson B, Daub CO

pmc

PLoS Negl Trop Dis 5 (8) e1283 [2011-08-00; online 2011-08-30]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Correlation between LRIG1 and LRIG2 expressions and expression of 11 tumor markers, with special reference to tumor suppressors, in CIN and normal cervical epithelium.

Lindström AK, Asplund A, Hellberg D

Gynecol. Oncol. 122 (2) 372-376 [2011-08-00; online 2011-06-03]

Tissue Profiling

PubMed DOI Crossref

Lack of association between genetic variations in the KALRN region and ischemic stroke.

Olsson S, Jood K, Melander O, ..., Lindgren A, Jern C

Clin. Biochem. 44 (12) 1018-1020 [2011-08-00; online 2011-06-15]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Antimicrobial susceptibility of Brachyspira spp. isolated from commercial laying hens and free-living wild mallards (Anas platyrhynchos).

Jansson DS, Pringle M

Avian Pathol. 40 (4) 387-393 [2011-08-00; online 2011-08-05]

NGI Uppsala (Uppsala Genome Center)

PubMed

RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer.

Ehlén Å, Nodin B, Rexhepaj E, ..., Brennan DJ, Jirström K

pmc

Transl Oncol 4 (4) 212-221 [2011-08-00; online 2011-08-01]

Tissue Profiling

PubMed DOI Crossref

Performance of ultra-deep pyrosequencing in analysis of HIV-1 pol gene variation.

Mild M, Hedskog C, Jernberg J, Albert J

pmc

PLoS ONE 6 (7) e22741 [2011-07-25; online 2011-07-25]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Structural alterations from multiple displacement amplification of a human genome revealed by mate-pair sequencing.

Jiao X, Rosenlund M, Hooper SD, ..., Mangion J, Sjöblom T

pmc

PLoS ONE 6 (7) e22250 [2011-07-22; online 2011-07-22]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Low RBM3 protein expression correlates with tumour progression and poor prognosis in malignant melanoma: an analysis of 215 cases from the Malmö Diet and Cancer Study.

Jonsson L, Bergman J, Nodin B, ..., Uhlén M, Jirström K

pmc

J Transl Med 9 (-) 114 [2011-07-21; online 2011-07-21]

Tissue Profiling

PubMed DOI Crossref

The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits.

Min JL, Taylor JM, Richards JB, ..., Spector TD, Zondervan KT

pmc

PLoS ONE 6 (7) e22070 [2011-07-15; online 2011-07-15]

Mutation Analysis Facility (MAF)

PubMed DOI Crossref

Scalable transcriptome preparation for massive parallel sequencing.

Stranneheim H, Werne B, Sherwood E, Lundeberg J

pmc

PLoS ONE 6 (7) e21910 [2011-07-07; online 2011-07-07]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Identification of noncoding transcripts from within CENP-A chromatin at fission yeast centromeres.

Choi ES, Strålfors A, Castillo AG, ..., Ekwall K, Allshire RC

pmc

J. Biol. Chem. 286 (26) 23600-23607 [2011-07-01; online 2011-05-03]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Potential association of muscarinic receptor 3 gene variants with primary Sjogren's syndrome.

Appel S, Le Hellard S, Bruland O, ..., Wahren-Herlenius M, Jonsson R

Ann. Rheum. Dis. 70 (7) 1327-1329 [2011-07-00; online 2011-04-01]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Species sorting and neutral processes are both important during the initial assembly of bacterial communities.

Langenheder S, Székely AJ

pmc

ISME J 5 (7) 1086-1094 [2011-07-00; online 2011-01-29]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Genetic architecture of circulating lipid levels.

Demirkan A, Amin N, Isaacs A, ..., van Duijn CM, ENGAGE CONSORTIUM

pmc

Eur. J. Hum. Genet. 19 (7) 813-819 [2011-07-00; online 2011-03-30]

NGI Uppsala (SNP&SEQ Technology Platform) [Service]

PubMed DOI Crossref

SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas.

Magnusson K, de Wit M, Brennan DJ, ..., Jirström K, Pontén F

Am. J. Surg. Pathol. 35 (7) 937-948 [2011-07-00; online 2011-06-17]

Cell Profiling Tissue Profiling

PubMed DOI Crossref

Concomitant autoimmunity in myasthenia gravis--lack of association with IgA deficiency.

Ramanujam R, Piehl F, Pirskanen R, Gregersen PK, Hammarström L

pmc mid

J. Neuroimmunol. 236 (1-2) 118-122 [2011-07-00; online 2011-06-15]

Mutation Analysis Facility (MAF)

PubMed DOI Crossref

Replication and explorations of high-order epistasis using a large advanced intercross line pedigree.

Pettersson M, Besnier F, Siegel PB, Carlborg O

pmc

PLoS Genet. 7 (7) e1002180 [2011-07-00; online 2011-07-21]

NGI Uppsala (SNP&SEQ Technology Platform) [Service]

PubMed DOI Crossref

Prostasomal DNA characterization and transfer into human sperm.

Ronquist GK, Larsson A, Ronquist G, ..., Carlsson L, Stavreus-Evers A

Mol. Reprod. Dev. 78 (7) 467-476 [2011-07-00; online 2011-06-04]

Array and Analysis Facility

PubMed DOI Crossref

Genome wide association study identifies KCNMA1 contributing to human obesity.

Jiao H, Arner P, Hoffstedt J, ..., Clement K, Dahlman I

pmc

BMC Med Genomics 4 (-) 51 [2011-06-28; online 2011-06-28]

Bioinformatics and Expression Analysis (BEA) Mutation Analysis Facility (MAF) NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.

Kilpeläinen TO, Zillikens MC, Stančákova A, ..., Laakso M, Loos RJ

pmc mid

Nat. Genet. 43 (8) 753-760 [2011-06-26; online 2011-06-26]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Specific syndecan-1 domains regulate mesenchymal tumor cell adhesion, motility and migration.

Zong F, Fthenou E, Mundt F, ..., Hjerpe A, Dobra K

pmc

PLoS ONE 6 (6) e14816 [2011-06-23; online 2011-06-23]

Bioinformatics and Expression Analysis (BEA)

PubMed DOI Crossref

KIT pathway alterations in mucosal melanomas of the vulva and other sites.

Omholt K, Grafström E, Kanter-Lewensohn L, Hansson J, Ragnarsson-Olding BK

Clin. Cancer Res. 17 (12) 3933-3942 [2011-06-15; online 2011-06-18]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Translational database selection and multiplexed sequence capture for up front filtering of reliable breast cancer biomarker candidates.

Ståhl PL, Bjursell MK, Mahdessian H, ..., Jirström K, Lundeberg J

pmc

PLoS ONE 6 (6) e20794 [2011-06-15; online 2011-06-15]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

(R,S)-dichlorprop herbicide in agricultural soil induces proliferation and expression of multiple dioxygenase-encoding genes in the indigenous microbial community.

Paulin MM, Nicolaisen MH, Sørensen J

GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK

Environ. Microbiol. 13 (6) 1513-1523 [2011-06-00; online 2011-03-23]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Genetic association and gene expression analysis identify FGFR1 as a new susceptibility gene for human obesity.

Jiao H, Arner P, Dickson SL, ..., Clement K, Dahlman I

J. Clin. Endocrinol. Metab. 96 (6) E962-E966 [2011-06-00; online 2011-03-25]

Bioinformatics and Expression Analysis (BEA) Mutation Analysis Facility (MAF) NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men.

Benedict C, Jacobsson JA, Rönnemaa E, ..., Kilander L, Schiöth HB

Neurobiol. Aging 32 (6) 1159.e1-1159.e5 [2011-06-00; online 2011-04-05]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Cytochrome P450 1A, 1B, and 1C mRNA induction patterns in three-spined stickleback exposed to a transient and a persistent inducer.

Gao K, Brandt I, Goldstone JV, Jönsson ME

pmc mid

Comp. Biochem. Physiol. C Toxicol. Pharmacol. 154 (1) 42-55 [2011-06-00; online 2011-03-01]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Feather pecking behavior in laying hens: hypothalamic gene expression in birds performing and receiving pecks.

Brunberg E, Jensen P, Isaksson A, Keeling L

Poult. Sci. 90 (6) 1145-1152 [2011-06-00; online 2011-05-21]

Array and Analysis Facility

PubMed DOI Crossref

Co-occurring SHOC2 and PTPN11 mutations in a patient with severe/complex Noonan syndrome-like phenotype.

Ekvall S, Hagenäs L, Allanson J, Annerén G, Bondeson ML

Am. J. Med. Genet. A 155A (6) 1217-1224 [2011-06-00; online 2011-05-07]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Tepidanaerobacter acetatoxydans sp. nov., an anaerobic, syntrophic acetate-oxidizing bacterium isolated from two ammonium-enriched mesophilic methanogenic processes.

Westerholm M, Roos S, Schnürer A

GENBANK GENBANK GENBANK GENBANK

Syst. Appl. Microbiol. 34 (4) 260-266 [2011-06-00; online 2011-04-19]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly.

Jacobsson JA, Almén MS, Benedict C, ..., Lind L, Schiöth HB

pmc

PLoS ONE 6 (5) e20158 [2011-05-27; online 2011-05-27]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer.

Tavoosidana G, Ronquist G, Darmanis S, ..., Landegren UD, Kamali-Moghaddam M

pmc

Proc. Natl. Acad. Sci. U.S.A. 108 (21) 8809-8814 [2011-05-24; online 2011-05-11]

Clinical Biomarkers PLA and Single Cell Proteomics

PubMed DOI Crossref

Sequence and generation of mature ribosomal RNA transcripts in Dictyostelium discoideum.

Boesler C, Kruse J, Söderbom F, Hammann C

pmc GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK GENBANK

J. Biol. Chem. 286 (20) 17693-17703 [2011-05-20; online 2011-04-02]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

A roadmap to generate renewable protein binders to the human proteome.

Colwill K, Renewable Protein Binder Working Group , Gräslund S

Nat. Methods 8 (7) 551-558 [2011-05-15; online 2011-05-15]

Autoimmunity Profiling [Technology development] Plasma Profiling [Technology development]

PubMed DOI Crossref

Cardio-facio-cutaneous syndrome: does genotype predict phenotype?

Allanson JE, Annerén G, Aoki Y, ..., Verloes A, Zenker M

pmc mid

Am J Med Genet C Semin Med Genet 157C (2) 129-135 [2011-05-15; online 2011-04-16]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Experimental evidence supports a sex-specific selective sieve in mitochondrial genome evolution.

Innocenti P, Morrow EH, Dowling DK

GEO

Science 332 (6031) 845-848 [2011-05-13; online 2011-05-14]

Array and Analysis Facility

PubMed DOI Crossref

Cys-X scanning for expansion of active-site residues and modulation of catalytic functions in a glutathione transferase.

Norrgård MA, Hellman U, Mannervik B

pmc

J. Biol. Chem. 286 (19) 16871-16878 [2011-05-13; online 2011-04-02]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Methods for Analysis of Transcription Factor DNA-Binding Specificity In Vitro.

Jolma A, Taipale J

Subcell. Biochem. 52 (-) 155-173 [2011-05-11; online 2011-05-11]

Karolinska High Throughput Center (KHTC)

PubMed DOI Crossref

Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer.

Wallin U, Glimelius B, Jirström K, ..., Påhlman L, Birgisson H

pmc

Br. J. Cancer 104 (10) 1619-1627 [2011-05-10; online 2011-04-07]

Tissue Profiling

PubMed DOI Crossref

Melanoma cells produce multiple laminin isoforms and strongly migrate on α5 laminin(s) via several integrin receptors.

Oikawa Y, Hansson J, Sasaki T, ..., Tryggvason K, Patarroyo M

Exp. Cell Res. 317 (8) 1119-1133 [2011-05-01; online 2011-01-05]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Characterization of NPY Y2 receptor protein expression in the mouse brain. II. Coexistence with NPY, the Y1 receptor, and other neurotransmitter-related molecules.

Stanić D, Mulder J, Watanabe M, Hökfelt T

J. Comp. Neurol. 519 (7) 1219-1257 [2011-05-01; online 2011-04-01]

Fluorescence Tissue Profiling

PubMed DOI Crossref

Directional genetic selection by pulp mill effluent on multiple natural populations of three-spined stickleback (Gasterosteus aculeatus).

Lind EE, Grahn M

pmc

Ecotoxicology 20 (3) 503-512 [2011-05-00; online 2011-04-02]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

The 12q14 microdeletion syndrome: six new cases confirming the role of HMGA2 in growth.

Lynch SA, Foulds N, Thuresson AC, ..., Ennis S, Sharkey F

pmc

Eur. J. Hum. Genet. 19 (5) 534-539 [2011-05-00; online 2011-01-27]

Array and Analysis Facility NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Parental criticism and externalizing behavior problems in adolescents: the role of environment and genotype-environment correlation.

Narusyte J, Neiderhiser JM, Andershed AK, ..., Ganiban J, Lichtenstein P

pmc mid

J Abnorm Psychol 120 (2) 365-376 [2011-05-00; online 2011-02-02]

Mutation Analysis Facility (MAF)

PubMed DOI Crossref

Nitrogenase gene amplicons from global marine surface waters are dominated by genes of non-cyanobacteria.

Farnelid H, Andersson AF, Bertilsson S, ..., Hagström Å, Riemann L

pmc

PLoS ONE 6 (4) e19223 [2011-04-29; online 2011-04-29]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Large scale library generation for high throughput sequencing.

Borgström E, Lundin S, Lundeberg J

pmc

PLoS ONE 6 (4) e19119 [2011-04-27; online 2011-04-27]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

Jakobsen L, Vanselow K, Skogs M, ..., Hyman AA, Andersen JS

pmc

EMBO J. 30 (8) 1520-1535 [2011-04-20; online 2011-03-15]

Cell Profiling

PubMed DOI Crossref

Structure and assembly-disassembly properties of wild-type transthyretin amyloid protofibrils observed with atomic force microscopy.

Pires RH, Saraiva MJ, Damas AM, Kellermayer MS

J. Mol. Recognit. 24 (3) 467-476 [2011-04-20; online 2011-04-20]

Mass Spectrometry-based Proteomics, Uppsala

PubMed DOI Crossref

Clostridium botulinum group III: a group with dual identity shaped by plasmids, phages and mobile elements.

Skarin H, Håfström T, Westerberg J, Segerman B

pmc

BMC Genomics 12 (-) 185 [2011-04-12; online 2011-04-12]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Synthesis and application of a bromomethyl substituted scaffold to be used for efficient optimization of anti-virulence activity.

Chorell E, Bengtsson C, Sainte-Luce Banchelin T, ..., Hultgren SJ, Almqvist F

pmc mid

Eur J Med Chem 46 (4) 1103-1116 [2011-04-00; online 2011-02-15]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

PubMed DOI Crossref

A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE.

Sandling JK, Garnier S, Sigurdsson S, ..., Rönnblom L, Syvänen AC

pmc

Eur. J. Hum. Genet. 19 (4) 479-484 [2011-04-00; online 2010-12-24]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: an association study.

Holtze M, Saetre P, Erhardt S, ..., Jönsson EG, Schalling M

Schizophr. Res. 127 (1-3) 270-272 [2011-04-00; online 2010-10-30]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Utilizing twins concordance rates to infer the predisposition to myasthenia gravis.

Ramanujam R, Pirskanen R, Ramanujam S, Hammarström L

Twin Res Hum Genet 14 (2) 129-136 [2011-04-00; online 2011-03-24]

Mutation Analysis Facility (MAF)

PubMed DOI Crossref

FATP4 missense and nonsense mutations cause similar features in Ichthyosis Prematurity Syndrome.

Sobol M, Dahl N, Klar J

pmc

BMC Res Notes 4 (-) 90 [2011-03-30; online 2011-03-30]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Human oral, gut, and plaque microbiota in patients with atherosclerosis.

Koren O, Spor A, Felin J, ..., Ley RE, Bäckhed F

pmc

Proc. Natl. Acad. Sci. U.S.A. 108 Suppl 1 (-) 4592-4598 [2011-03-15; online 2010-10-13]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP).

Hashemi J, Worrall C, Vasilcanu D, ..., Larsson O, Larsson C

pmc

PLoS ONE 6 (3) e14757 [2011-03-14; online 2011-03-14]

Mutation Analysis Facility (MAF)

PubMed

An assessment of CETP sequence variation in relation to cognitive decline and dementia risk.

Reynolds CA, Gatz M, Pedersen NL, Prince JA

pmc

Int J Mol Epidemiol Genet 2 (2) 122-129 [2011-03-10; online 2011-03-10]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Decoding a substantial set of samples in parallel by massive sequencing.

Neiman M, Lundin S, Savolainen P, Ahmadian A

pmc

PLoS ONE 6 (3) e17785 [2011-03-09; online 2011-03-09]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.

Coronary Artery Disease (C4D) Genetics Consortium

Nat. Genet. 43 (4) 339-344 [2011-03-06; online 2011-03-06]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Antibody suspension bead arrays.

Schwenk JM, Nilsson P

Methods Mol. Biol. 723 (-) 29-36 [2011-03-04; online 2011-03-04]

Plasma Profiling [Technology development]

PubMed DOI Crossref

Bioinformatic tools for using whole genome sequencing as a rapid high resolution diagnostic typing tool when tracing bioterror organisms in the food and feed chain.

Segerman B, De Medici D, Ehling Schulz M, ..., Van Rotterdam B, Knutsson R

Int. J. Food Microbiol. 145 Suppl 1 (-) S167-S176 [2011-03-01; online 2010-09-10]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome.

Nordmark G, Kristjansdottir G, Theander E, ..., Jonsson R, Syvänen AC

Genes Immun. 12 (2) 100-109 [2011-03-00; online 2010-09-24]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.

Ameur A, Stewart JB, Freyer C, ..., Larsson N, Gyllensten U

pmc

PLoS Genet. 7 (3) e1002028 [2011-03-00; online 2011-03-24]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

CUBN is a gene locus for albuminuria.

Böger CA, Chen MH, Tin A, ..., Fox CS, Kao WH

pmc

J. Am. Soc. Nephrol. 22 (3) 555-570 [2011-03-00; online 2011-03-01]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

A novel unstable duplication upstream of HAS2 predisposes to a breed-defining skin phenotype and a periodic fever syndrome in Chinese Shar-Pei dogs.

Olsson M, Meadows JRS, Truvé K, ..., Tintle L, Lindblad-Toh K

pmc

PLoS Genet. 7 (3) e1001332 [2011-03-00; online 2011-03-17]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.

Speliotes EK, Yerges-Armstrong LM, Wu J, ..., Borecki IB, GOLD Consortium

pmc

PLoS Genet. 7 (3) e1001324 [2011-03-00; online 2011-03-10]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Systematic antibody and antigen-based proteomic profiling with microarrays.

Ayoglu B, Häggmark A, Neiman M, ..., Schwenk JM, Nilsson P

Expert Rev. Mol. Diagn. 11 (2) 219-234 [2011-03-00; online 2011-03-17]

Autoimmunity Profiling [Technology development] Plasma Profiling [Technology development]

PubMed DOI Crossref

Expression of 5,8-LDS of Aspergillus fumigatus and its dioxygenase domain. A comparison with 7,8-LDS, 10-dioxygenase, and cyclooxygenase.

Hoffmann I, Jernerén F, Garscha U, Oliw EH

Arch. Biochem. Biophys. 506 (2) 216-222 [2011-02-15; online 2010-12-07]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Identification of epigenetically regulated genes that predict patient outcome in neuroblastoma.

Carén H, Djos A, Nethander M, ..., Nilsson S, Martinsson T

pmc

BMC Cancer 11 (-) 66 [2011-02-11; online 2011-02-11]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Performance of microarray and liquid based capture methods for target enrichment for massively parallel sequencing and SNP discovery.

Kiialainen A, Karlberg O, Ahlford A, ..., Lindblad-Toh K, Syvänen AC

pmc

PLoS ONE 6 (2) e16486 [2011-02-09; online 2011-02-09]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Genetic association of sequence variants near AGER/NOTCH4 and dementia.

Bennet AM, Reynolds CA, Eriksson UK, ..., Pedersen NL, Prince JA

pmc mid

J. Alzheimers Dis. 24 (3) 475-484 [2011-02-08; online 2011-02-08]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Diagnostic biomarkers of prostate cancer.

Häggarth L, Hägglöf C, Jaraj SJ, ..., Ostman A, Egevad L

Scand. J. Urol. Nephrol. 45 (1) 60-67 [2011-02-00; online 2010-11-03]

Tissue Profiling

PubMed DOI Crossref

The Swedish new variant of Chlamydia trachomatis.

Unemo M, Clarke IN

Curr. Opin. Infect. Dis. 24 (1) 62-69 [2011-02-00; online 2010-12-16]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

GAD1 is a biomarker for benign and malignant prostatic tissue.

Jaraj SJ, Augsten M, Häggarth L, ..., Ostman A, Egevad L

Scand. J. Urol. Nephrol. 45 (1) 39-45 [2011-02-00; online 2010-11-26]

Tissue Profiling

PubMed DOI Crossref

Sun-induced nonsynonymous p53 mutations are extensively accumulated and tolerated in normal appearing human skin.

Ståhl PL, Stranneheim H, Asplund A, ..., Pontén F, Lundeberg J

J. Invest. Dermatol. 131 (2) 504-508 [2011-02-00; online 2010-10-15]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Common pathogenetic mechanism involving human chromosome 18 in familial and sporadic ileal carcinoid tumors.

Cunningham JL, Díaz de Ståhl T, Sjöblom T, ..., Dumanski JP, Janson ET

Genes Chromosomes Cancer 50 (2) 82-94 [2011-02-00; online 2010-11-26]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

L'Episcopo F, Tirolo C, Testa N, ..., Pluchino S, Marchetti B

pmc mid

Neurobiol. Dis. 41 (2) 508-527 [2011-02-00; online 2010-11-09]

Bioinformatics and Expression Analysis (BEA)

PubMed DOI Crossref

High-resolution genomic screening in mantle cell lymphoma--specific changes correlate with genomic complexity, the proliferation signature and survival.

Halldórsdóttir AM, Sander B, Göransson H, ..., Rosenquist R, Ehrencrona H

Genes Chromosomes Cancer 50 (2) 113-121 [2011-02-00; online 2010-12-01]

Array and Analysis Facility NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production)

PubMed DOI Crossref

Genetic variation on chromosome 9p21 shows association with the ischaemic stroke subtype large-vessel disease in a Swedish sample aged ≤ 70.

Olsson S, Jood K, Blomstrand C, Jern C

Eur. J. Neurol. 18 (2) 365-367 [2011-02-00; online 2010-05-27]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen.

Brennan DJ, Laursen H, O'Connor DP, ..., Rydén L, Jirström K

pmc

Breast Cancer Res. 13 (1) R12 [2011-01-31; online 2011-01-31]

Tissue Profiling

PubMed DOI Crossref

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF.

Rolny C, Mazzone M, Tugues S, ..., Claesson-Welsh L, Carmeliet P

Cancer Cell 19 (1) 31-44 [2011-01-18; online 2011-01-11]

Tissue Profiling

PubMed DOI Crossref

Fine mapping and replication of QTL in outbred chicken advanced intercross lines.

Besnier F, Wahlberg P, Rönnegård L, ..., Siegel PB, Carlborg O

pmc

Genet. Sel. Evol. 43 (1) 3 [2011-01-17; online 2011-01-17]

NGI Uppsala (SNP&SEQ Technology Platform)

PubMed DOI Crossref

New CYP1 genes in the frog Xenopus (Silurana) tropicalis: induction patterns and effects of AHR agonists during development.

Jönsson ME, Berg C, Goldstone JV, Stegeman JJ

pmc mid

Toxicol. Appl. Pharmacol. 250 (2) 170-183 [2011-01-15; online 2010-10-23]

NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

A systems biology model of the regulatory network in Populus leaves reveals interacting regulators and conserved regulation.

Street NR, Jansson S, Hvidsten TR

pmc

BMC Plant Biol. 11 (-) 13 [2011-01-13; online 2011-01-13]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Vitamin D receptor genotypes, ultraviolet radiation exposure, and risk of non-Hodgkin lymphoma.

Smedby KE, Eloranta S, Duvefelt K, ..., Hjalgrim H, Chang ET

Am. J. Epidemiol. 173 (1) 48-54 [2011-01-01; online 2010-11-16]

Mutation Analysis Facility (MAF)

PubMed DOI Crossref

Mechanisms of blast induced brain injuries, experimental studies in rats.

Risling M, Plantman S, Angeria M, ..., Arborelius U, Davidsson J

Neuroimage 54 Suppl 1 (-) S89-S97 [2011-01-00; online 2010-05-25]

Bioinformatics and Expression Analysis (BEA)

PubMed DOI Crossref

Targeted resequencing of candidate genes using selector probes.

Johansson H, Isaksson M, Sörqvist EF, ..., Ericsson O, Nilsson M

pmc

Nucleic Acids Res. 39 (2) e8 [2011-01-00; online 2010-11-10]

Array and Analysis Facility NGI Uppsala (Uppsala Genome Center)

PubMed DOI Crossref

Structure and etiology of co-occurring internalizing and externalizing disorders in adolescents.

Cosgrove VE, Rhee SH, Gelhorn HL, ..., Young SE, Hewitt JK

pmc mid

J Abnorm Child Psychol 39 (1) 109-123 [2011-01-00; online 2010-08-05]

Mutation Analysis Facility (MAF)

PubMed DOI Crossref

Meta-analysis of the association between variants in SORL1 and Alzheimer disease.

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