Concomitant autoimmunity in myasthenia gravis--lack of association with IgA deficiency.

Ramanujam R, Piehl F, Pirskanen R, Gregersen PK, Hammarström L

J. Neuroimmunol. 236 (1-2) 118-122 [2011-07-00; online 2011-06-15]

A marked increase in concomitant autoimmune diseases has previously been noted in patients with myasthenia gravis (MG). We show that these diseases occur both before and after the onset of MG and that the process is not influenced by thymectomy. IgA deficiency (IgAD), which is strongly associated with the same HLA haplotype as early onset MG, has recently been suggested to be an autoimmune disease. However, there was no increase in the prevalence of IgAD in a large cohort of Swedish MG patients.

Mutation Analysis Facility (MAF)

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PubMed 21669464

DOI 10.1016/j.jneuroim.2011.05.008

Crossref 10.1016/j.jneuroim.2011.05.008

mid NIHMS305414

S0165-5728(11)00138-X

pmc PMC3230785