Lack of association between genetic variations in the KALRN region and ischemic stroke.

Olsson S, Jood K, Melander O, Sjögren M, Norrving B, Nilsson M, Lindgren A, Jern C

Clin. Biochem. 44 (12) 1018-1020 [2011-08-00; online 2011-06-15]

To investigate whether KALRN gene variation is associated with ischemic stroke (IS). Associations to overall IS and IS subtypes were investigated in SAHLSIS, which comprises 844 patients with IS and 668 controls. Associations between KALRN SNPs and overall IS and cardioembolic stroke were detected. Associations for overall IS were investigated in two additional Swedish samples, but could not be replicated. KALRN gene variation is not associated with overall IS.

NGI Uppsala (SNP&SEQ Technology Platform)

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PubMed 21664346

DOI 10.1016/j.clinbiochem.2011.05.025

Crossref 10.1016/j.clinbiochem.2011.05.025

S0009-9120(11)00376-6