Human population dynamics and Yersinia pestis in ancient northeast Asia.

Kılınç GM, Kashuba N, Koptekin D, Bergfeldt N, Dönertaş HM, Rodríguez-Varela R, Shergin D, Ivanov G, Kichigin D, Pestereva K, Volkov D, Mandryka P, Kharinskii A, Tishkin A, Ineshin E, Kovychev E, Stepanov A, Dalén L, Günther T, Kırdök E, Jakobsson M, Somel M, Krzewińska M, Storå J, Götherström A

Sci Adv 7 (2) - [2021-01-00; online 2021-01-06]

We present genome-wide data from 40 individuals dating to c.16,900 to 550 years ago in northeast Asia. We describe hitherto unknown gene flow and admixture events in the region, revealing a complex population history. While populations east of Lake Baikal remained relatively stable from the Mesolithic to the Bronze Age, those from Yakutia and west of Lake Baikal witnessed major population transformations, from the Late Upper Paleolithic to the Neolithic, and during the Bronze Age, respectively. We further locate the Asian ancestors of Paleo-Inuits, using direct genetic evidence. Last, we report the most northeastern ancient occurrence of the plague-related bacterium, Yersinia pestis Our findings indicate the highly connected and dynamic nature of northeast Asia populations throughout the Holocene.

NGI Stockholm (Genomics Applications)

NGI Stockholm (Genomics Production)

National Genomics Infrastructure

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PubMed 33523963

DOI 10.1126/sciadv.abc4587

Crossref 10.1126/sciadv.abc4587

pii: 7/2/eabc4587
pmc: PMC7787494