Publications 2010

139 publications

SOX10 expression in superficial spreading and nodular malignant melanomas.
Agnarsdóttir M, Sooman L, Bolander A, ..., Uhlen M, Hedstrand H
Melanoma Res. 20 (6) 468-478 [2010-12-00; online 2010-10-05]
Tissue Profiling
Towards a knowledge-based Human Protein Atlas.
Uhlen M, Oksvold P, Fagerberg L, ..., Björling L, Ponten F
pii: nbt1210-1248
Nat. Biotechnol. 28 (12) 1248-1250 [2010-12-00; online 2010-12-09]
Autoimmunity and Serology Profiling [Technology development] Cell Profiling
Creation of an antibody-based subcellular protein atlas.
Lundberg E, Uhlén M
Proteomics 10 (22) 3984-3996 [2010-11-00; online 2010-07-22]
Cell Profiling
Sensitive detection of Aβ protofibrils by proximity ligation--relevance for Alzheimer's disease.
Kamali-Moghaddam M, Pettersson FE, Wu D, ..., Lannfelt L, Landegren U
pii: 1471-2202-11-124 pmc: PMC2959092
BMC Neurosci 11 (-) 124 [2010-10-05; online 2010-10-05]
PLA and Single Cell Proteomics
Linkage to 20p13 including the ANGPT4 gene in families with mixed Alzheimer's disease and vascular dementia.
Sillén A, Brohede J, Lilius L, ..., Winblad B, Graff C
pii: jhg201079
J. Hum. Genet. 55 (10) 649-655 [2010-10-00; online 2010-07-03]
Mutation Analysis Facility (MAF)
A chromatin-remodeling protein is a component of fission yeast mediator.
Khorosjutina O, Wanrooij PH, Walfridsson J, ..., Ekwall K, Gustafsson CM
pii: M110.153858 pmc: PMC2943280
J. Biol. Chem. 285 (39) 29729-29737 [2010-09-24; online 2010-07-14]
Bioinformatics and Expression Analysis (BEA)
Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.
Ferreira RC, Pan-Hammarström Q, Graham RR, ..., Behrens TW, Hammarström L
pii: ng.644
Nat. Genet. 42 (9) 777-780 [2010-09-00; online 2010-08-10]
Mutation Analysis Facility (MAF)
Topoisomerase I amplification in melanoma is associated with more advanced tumours and poor prognosis.
Ryan D, Rafferty M, Hegarty S, ..., Dervan PA, Gallagher WM
pii: PCR720
Pigment Cell Melanoma Res 23 (4) 542-553 [2010-08-00; online 2010-05-15]
Tissue Profiling
Different SNP combinations in the GCH1 gene and use of labor analgesia.
Dabo F, Grönbladh A, Nyberg F, Sundström-Poromaa I, Akerud H
pii: 1744-8069-6-41 pmc: PMC2912270
Mol Pain 6 (-) 41 [2010-07-15; online 2010-07-15]
NGI Uppsala (Uppsala Genome Center) National Genomics Infrastructure
Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo.
Wei GH, Badis G, Berger MF, ..., Bulyk ML, Taipale J
pii: emboj2010106 pmc: PMC2905244
EMBO J. 29 (13) 2147-2160 [2010-07-07; online 2010-06-03]
Karolinska High Throughput Center (KHTC)
Topoisomerase I regulates open chromatin and controls gene expression in vivo.
Durand-Dubief M, Persson J, Norman U, Hartsuiker E, Ekwall K
pii: emboj2010109 pmc: PMC2905247
EMBO J. 29 (13) 2126-2134 [2010-07-07; online 2010-06-08]
Bioinformatics and Expression Analysis (BEA)
Gene expression analysis in hypoplastic lungs in the nitrofen model of congenital diaphragmatic hernia.
Burgos CM, Uggla AR, Fagerström-Billai F, ..., Frenckner B, Nord M
pii: S0022-3468(09)00764-7
J. Pediatr. Surg. 45 (7) 1445-1454 [2010-07-00; online 2010-07-20]
Bioinformatics and Expression Analysis (BEA)
Ontogenetic complexity of sexual dimorphism and sex-specific selection.
Mank JE, Nam K, Brunström B, Ellegren H
pii: msq042
Mol. Biol. Evol. 27 (7) 1570-1578 [2010-07-00; online 2010-02-10]
Array and Analysis Facility
Genetic evidence of multiple loci in dystocia--difficult labour.
Algovik M, Kivinen K, Peterson H, Westgren M, Kere J
pii: 1471-2350-11-105 pmc: PMC2914646
BMC Med. Genet. 11 (-) 105 [2010-06-30; online 2010-06-30]
Bioinformatics and Expression Analysis (BEA)
Alpha terpineol: a potential anticancer agent which acts through suppressing NF-kappaB signalling.
Hassan SB, Gali-Muhtasib H, Göransson H, Larsson R
pii: 30/6/1911
Anticancer Res. 30 (6) 1911-1919 [2010-06-00; online 2010-07-24]
Array and Analysis Facility
Improving Bayesian credibility intervals for classifier error rates using maximum entropy empirical priors.
Gustafsson MG, Wallman M, Wickenberg Bolin U, ..., Andersson CR, Isaksson A
pii: S0933-3657(10)00025-4
Artif Intell Med 49 (2) 93-104 [2010-06-00; online 2010-03-30]
Array and Analysis Facility
A variant near the interleukin-6 gene is associated with fat mass in Caucasian men.
Andersson N, Strandberg L, Nilsson S, ..., Jansson JO, Osteoporotic Fractures in Men MrOS Research Group
Int J Obes (Lond) 34 (6) 1011-1019 [2010-06-00; online 2010-02-17]
NGI Uppsala (SNP&SEQ Technology Platform) National Genomics Infrastructure
Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets.
Lindskog C, Asplund A, Engkvist M, ..., Korsgren O, Ponten F
Discov Med 9 (49) 565-578 [2010-06-00; online 2010-07-01]
Tissue Profiling
Genetics of HPA-axis, depression and suicidality.
Wasserman D, Wasserman J, Sokolowski M
pii: S0924-9338(10)00062-3
Eur. Psychiatry 25 (5) 278-280 [2010-06-00; online 2010-05-07]
NGI Uppsala (SNP&SEQ Technology Platform) National Genomics Infrastructure
Adipose tissue pathways involved in weight loss of cancer cachexia.
Dahlman I, Mejhert N, Linder K, ..., Rydén M, Arner P
pii: 6605665 pmc: PMC2869165
Br. J. Cancer 102 (10) 1541-1548 [2010-05-11; online 2010-04-22]
Bioinformatics and Expression Analysis (BEA)
Gene-specific and global methylation patterns predict outcome in patients with acute myeloid leukemia.
Deneberg S, Grövdal M, Karimi M, ..., Hellström-Lindberg E, Lehmann S
pii: leu201041
Leukemia 24 (5) 932-941 [2010-05-00; online 2010-03-20]
Bioinformatics and Expression Analysis (BEA)
Mapping of the fibroblast growth factors in human white adipose tissue.
Mejhert N, Galitzky J, Pettersson AT, ..., Arner P, Rydén M
pii: jc.2009-2049
J. Clin. Endocrinol. Metab. 95 (5) 2451-2457 [2010-05-00; online 2010-03-17]
Bioinformatics and Expression Analysis (BEA)
A single fixation protocol for proteome-wide immunofluorescence localization studies.
Stadler C, Skogs M, Brismar H, Uhlén M, Lundberg E
pii: S1874-3919(09)00310-8
J Proteomics 73 (6) 1067-1078 [2010-04-18; online 2009-11-10]
Cell Profiling
Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer.
Brennan DJ, Brändstedt J, Rexhepaj E, ..., O'Herlihy C, Jirstrom K
pii: 1471-2407-10-125 pmc: PMC3087316
BMC Cancer 10 (-) 125 [2010-04-01; online 2010-04-01]
Tissue Profiling
The recombination landscape of the zebra finch Taeniopygia guttata genome.
Backström N, Forstmeier W, Schielzeth H, ..., Kempenaers B, Ellegren H
pii: gr.101410.109 pmc: PMC2847751
Genome Res. 20 (4) 485-495 [2010-04-00; online 2010-03-31]
NGI Uppsala (SNP&SEQ Technology Platform) National Genomics Infrastructure
ELMOD2, a candidate gene for idiopathic pulmonary fibrosis, regulates antiviral responses.
Pulkkinen V, Bruce S, Rintahaka J, ..., Matikainen S, Kere J
pii: fj.09-138545
FASEB J. 24 (4) 1167-1177 [2010-04-00; online 2009-12-08]
Bioinformatics and Expression Analysis (BEA)
Sustained inflammation due to nuclear factor-kappa B activation in irradiated human arteries.
Halle M, Gabrielsen A, Paulsson-Berne G, ..., Farnebo F, Tornvall P
pii: S0735-1097(10)00142-7
J. Am. Coll. Cardiol. 55 (12) 1227-1236 [2010-03-23; online 2010-03-20]
Bioinformatics and Expression Analysis (BEA)
Appearance of Cxcl10-expressing cell clusters is common for traumatic brain injury and neurodegenerative disorders.
Israelsson C, Bengtsson H, Lobell A, ..., Hillered L, Ebendal T
pii: EJN7105
Eur. J. Neurosci. 31 (5) 852-863 [2010-03-00; online 2010-04-09]
Array and Analysis Facility
The impact of tissue fixatives on morphology and antibody-based protein profiling in tissues and cells.
Paavilainen L, Edvinsson A, Asplund A, ..., Pontén F, Wester K
pii: jhc.2009.954321 pmc: PMC2825489
J. Histochem. Cytochem. 58 (3) 237-246 [2010-03-00; online 2009-11-11]
Tissue Profiling
Sensitive plasma protein analysis by microparticle-based proximity ligation assays.
Darmanis S, Nong RY, Hammond M, ..., Landegren U, Kamali-Moghaddam M
pii: M900248-MCP200 pmc: PMC2830843
Mol. Cell Proteomics 9 (2) 327-335 [2010-02-00; online 2009-12-04]
PLA and Single Cell Proteomics
Genetic and biochemical studies of SNPs of the mitochondrial A beta-degrading protease, hPreP.
Pinho CM, Björk BF, Alikhani N, ..., Glaser E, Graff C
pii: S0304-3940(09)01566-3
Neurosci. Lett. 469 (2) 204-208 [2010-01-22; online 2009-12-08]
Mutation Analysis Facility (MAF)
Tissue-Specific Protein Expression in Human Cells, Tissues and Organs
Gry M, Oksvold P, Pontén F, Uhlén M
JPB 03 (10) - [2010-00-00; online 2010-00-00]
Tissue Profiling