Peña-Martinez P

Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases.

Thorsson H, Henningsson R, Puente-Moncada N, ..., Lilljebjörn H, Fioretos T

Blood 144 (13) 1399-1411 [2024-09-26; online 2024-07-05]

Clinical Genomics [Service] Clinical Genomics Lund [Service]

Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity.

Rodriguez-Zabala M, Ramakrishnan R, Reinbach K, ..., Woods NB, Järås M

Blood Adv 7 (18) 5382-5395 [2023-09-26; online 2023-07-28]

Clinical Genomics [Service] Clinical Genomics Lund [Service] Swedish Metabolomics Centre [Service]

The complement receptor C3AR constitutes a novel therapeutic target in NPM1-mutated AML.

von Palffy S, Thorsson H, Peña-Martínez P, ..., Lilljebjörn H, Fioretos T

Blood Adv 7 (7) 1204-1218 [2023-04-11; online 2022-11-17]

Clinical Genomics [Service] Clinical Genomics Lund [Service]

Clonal competition within complex evolutionary hierarchies shapes AML over time.

Sandén C, Lilljebjörn H, Orsmark Pietras C, ..., Ågerstam H, Fioretos T

Nat Commun 11 (1) 579 [2020-02-05; online 2020-02-05]

Clinical Genomics Clinical Genomics Lund