Design and development of a photoswitchable DFG-out kinase inhibitor.

Xu Y, Gao C, Håversen L, Lundbäck T, Andréasson J, Grøtli M

Chem. Commun. (Camb.) 57 (78) 10043-10046 [2021-09-30; online 2021-09-30]

We report the synthesis and characterisation of a photoswitchable DFG-out kinase inhibitor. Photocontrol of the target kinase in both enzymatic and living cell assays is demonstrated.

Chemical Biology Consortium Sweden (CBCS) [Service]

PubMed 34505602

DOI 10.1039/d1cc04125h

Crossref 10.1039/d1cc04125h


Publications 7.1.2