Axelsson H

Image based subcellular mapping of the protein landscape of SARS-CoV-2 infected cells for target-centric drug repurposing.

Tampere M, H Le T, Asp E, ..., Östling P, Stadler C

Biomed Pharmacother 191 (-) 118447 [2025-08-16; online 2025-08-16]

Chemical Biology Consortium Sweden [Collaborative] Spatial Proteomics [Collaborative]

Subcellular mapping of the protein landscape of SARS-CoV-2 infected cells for target-centric drug repurposing

Kaimal JM, Tampere M, Le TH, ..., Östling P, Stadler C

- - (-) - [2022-03-29; online 2022-03-29]

Spatial Proteomics [Technology development]

Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells

Mathew NR, Jayanthan JK, Smirnov IV, ..., Bemark M, Angeletti D

Cell Rep 35 (12) 109286 [2021-06-00; online 2021-06-00]

Bioinformatics (NBIS) [Collaborative] Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Systems Biology [Collaborative]

A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens.

Vella P, Rudraraju RS, Lundbäck T, ..., Schneider G, Schnell R

Bioorg. Med. Chem. 30 (-) 115898 [2021-01-15; online 2020-12-05]

Chemical Biology Consortium Sweden [Collaborative]

Development of a chemical probe against NUDT15.

Zhang SM, Desroses M, Hagenkort A, ..., Stenmark P, Helleday T

Nat. Chem. Biol. 16 (10) 1120-1128 [2020-10-00; online 2020-07-20]

Chemical Biology Consortium Sweden [Collaborative] Protein Science Facility (PSF) [Service]

Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy.

Rudd SG, Tsesmetzis N, Sanjiv K, ..., Helleday T, Herold N

EMBO Mol Med 12 (3) e10419 [2020-03-06; online 2020-01-17]

Chemical Biology Consortium Sweden [Collaborative]

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.

Gad H, Koolmeister T, Jemth A, ..., Berglund UW, Helleday T

Nature 508 (7495) 215-221 [2014-04-10; online 2014-04-02]

Chemical Biology Consortium Sweden [Collaborative] Drug Discovery and Development [Collaborative] Protein Science Facility (PSF)