Pan-Hammarström Q

Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency.

Le Voyer T, Parent AV, Liu X, ..., Casanova JL, Puel A

Nature - (-) - [2023-11-08; online 2023-11-08]

Autoimmunity and Serology Profiling [Service]

Design, structure and plasma binding of ancestral β-CoV scaffold antigens.

Hueting D, Schriever K, Sun R, ..., Andréll J, Syrén PO

Nat Commun 14 (1) 6527 [2023-10-16; online 2023-10-16]

Cryo-EM [Service] Drug Discovery and Development (DDD) [Service]

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.

Matuozzo D, Talouarn E, Marchal A, ..., Abel L, Cobat A

medRxiv - (-) - [2022-10-25; online 2022-10-25]

Clinical Genomics Stockholm [Service]

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia.

Zhang Q, Matuozzo D, Le Pen J, ..., Cobat A, Casanova JL

J. Exp. Med. 219 (8) - [2022-08-01; online 2022-06-16]

Clinical Genomics Stockholm [Service]

Inherited IFNAR1 Deficiency in a Child with Both Critical COVID-19 Pneumonia and Multisystem Inflammatory Syndrome

Abolhassani H, Landegren N, Bastard P, ..., Hammarström L, Pan-Hammarström Q

J Clin Immunol 42 (3) 471-483 [2022-04-00; online 2022-01-28]

Autoimmunity and Serology Profiling [Service]

X-Linked TLR7 Deficiency Underlies Critical COVID-19 Pneumonia in a Male Patient with Ataxia-Telangiectasia.

Abolhassani H, Vosughimotlagh A, Asano T, ..., Hammarström L, Pan-Hammarström Q

J Clin Immunol - (-) - [2021-10-23; online 2021-10-23]

Autoimmunity and Serology Profiling [Service]

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.

Asano T, Boisson B, Onodi F, ..., Zhang Q, Casanova JL

Sci Immunol 6 (62) - [2021-08-19; online 2021-08-21]

Clinical Genomics Stockholm [Service]

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

Nie M, Du L, Ren W, ..., Zhang F, Pan-Hammarström Q

Cell Death Dis 12 (5) 419 [2021-04-28; online 2021-04-28]

Bioinformatics Compute and Storage [Service]