Tegel H

Engineered calcium-regulated affinity protein for efficient internalization and lysosomal toxin delivery.

Jönsson M, Möller M, Schierholz L, ..., Brismar H, Hober S

Proc. Natl. Acad. Sci. U.S.A. 122 (48) e2509081122 [2025-12-02; online 2025-11-25]

Integrated Microscopy Technologies Stockholm [Collaborative]

Deciphering the determinants of recombinant protein expression across the human secretome.

Masson HO, Di Giusto P, Kuo CC, ..., Rockberg J, Lewis NE

Proc. Natl. Acad. Sci. U.S.A. 122 (41) e2506036122 [2025-10-14; online 2025-10-07]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Deep sequencing combined with high-throughput screening enables efficient development of a pH-dependent high-affinity binding domain targeting HER3.

Möller M, Jönsson M, Lundqvist M, ..., Tegel H, Hober S

Protein Sci. 34 (8) e70247 [2025-08-00; online 2025-07-29]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Prevalent and persistent new-onset autoantibodies in mild to severe COVID-19.

Jernbom AF, Skoglund L, Pin E, ..., Månberg A, Nilsson P

Nat Commun 15 (1) 8941 [2024-10-17; online 2024-10-17]

Autoimmunity and Serology Profiling [Collaborative]

Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis.

Bronge M, Högelin KA, Thomas OG, ..., Olsson T, Grönlund H

Sci Adv 8 (17) eabn1823 [2022-04-29; online 2022-04-27]

Autoimmunity and Serology Profiling [Collaborative]

Systematic evaluation of SARS-CoV-2 antigens enables a highly specific and sensitive multiplex serological COVID-19 assay.

Hober S, Hellström C, Olofsson J, ..., Hedhammar M, Nilsson P

Clin Transl Immunology 10 (7) e1312 [2021-07-19; online 2021-07-19]

Autoimmunity and Serology Profiling [Technology development]

Enhanced validation of antibodies for research applications.

Edfors F, Hober A, Linderbäck K, ..., Forsström B, Uhlen M

Nat Commun 9 (1) 4130 [2018-10-08; online 2018-10-08]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

A subcellular map of the human proteome.

Thul PJ, Åkesson L, Wiking M, ..., Uhlén M, Lundberg E

Science 356 (6340) - [2017-05-26; online 2017-05-11]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Spatial Proteomics [Collaborative]