Lönnblom E

Antigen-presenting autoreactive B cells activate regulatory T cells and suppress autoimmune arthritis in mice.

Aoun M, Coelho A, Krämer A, ..., Burkhardt H, Holmdahl R

J. Exp. Med. 220 (11) - [2023-11-06; online 2023-09-11]

Bioinformatics (NBIS) [Service] Bioinformatics Support and Infrastructure [Service] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Service]

A subset of type-II collagen-binding antibodies prevents experimental arthritis by inhibiting FCGR3 signaling in neutrophils.

Xu Z, Xu B, Lundström SL, ..., Zubarev RA, Holmdahl R

Nat Commun 14 (1) 5949 [2023-09-23; online 2023-09-23]

Drug Discovery and Development (DDD) [Collaborative]

Pathogenic antibody response to glucose-6-phosphate isomerase targets a modified epitope uniquely exposed on joint cartilage.

Li T, Ge C, Krämer A, ..., Gjertsson I, Holmdahl R

Ann. Rheum. Dis. 82 (6) 799-808 [2023-06-00; online 2023-03-01]

Bioinformatics (NBIS) [Service] Bioinformatics Long-term Support WABI [Service] Bioinformatics Support, Infrastructure and Training [Service]