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Publications
Llona-Minguez S, Throup A, Steiner E, Lightowler M, Van der Haegen S, Homan E, Eriksson L, Stenmark P, Jenmalm-Jensen A, Helleday T
Org. Biomol. Chem. 15 (37) 7758-7764 [2017-09-26; online 2017-09-12]
Here we present a two-step diastereoselective methodology building on a multicomponent aza-Diels-Alder reaction. Using previously unexplored cyclic ketones, heterocyclic amines and cyclopentadiene derivatives, we obtained novel spiro-heterocyclic frameworks at the interphase between "drug-like" molecules and natural products.
Chemical Biology Consortium Sweden (CBCS) [Collaborative]
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PubMed 28891572
DOI 10.1039/c7ob02069d
Crossref 10.1039/c7ob02069d