{"entity": "publication", "iuid": "37442ab98d914bb1827ce6b803dae200", "timestamp": "2026-10-08T10:54:39.260Z", "links": {"self": {"href": "https://publications.scilifelab.se/publication/37442ab98d914bb1827ce6b803dae200.json"}, "display": {"href": "https://publications.scilifelab.se/publication/37442ab98d914bb1827ce6b803dae200"}}, "title": "A multi-step peptidolytic cascade for amino acid recovery in chloroplasts.", "authors": [{"family": "Teixeira", "given": "Pedro F", "initials": "PF", "orcid": "0000-0001-8638-7477", "researcher": {"href": "https://publications.scilifelab.se/researcher/9b43730fe20b424db84f091333be7244.json"}}, {"family": "Kmiec", "given": "Beata", "initials": "B"}, {"family": "Branca", "given": "Rui M M", "initials": "RM"}, {"family": "Murcha", "given": "Monika W", "initials": "MW", "orcid": "0000-0002-3689-6158", "researcher": {"href": "https://publications.scilifelab.se/researcher/49b1e7e1fca74be090072ad2185c9827.json"}}, {"family": "Byzia", "given": "Anna", "initials": "A"}, {"family": "Ivanova", "given": "Aneta", "initials": "A"}, {"family": "Whelan", "given": "James", "initials": "J"}, {"family": "Drag", "given": "Marcin", "initials": "M"}, {"family": "Lehti\u00f6", "given": "Janne", "initials": "J", "orcid": "0000-0002-8100-9562", "researcher": {"href": "https://publications.scilifelab.se/researcher/8406a97bac744a59b1bc951978994581.json"}}, {"family": "Glaser", "given": "Elzbieta", "initials": "E"}], "type": "journal article", "published": "2017-01-00", "journal": {"volume": "13", "issn": "1552-4469", "issue": "1", "pages": "15-17", "title": "Nat. Chem. Biol.", "issn-l": "1552-4450"}, "abstract": "Plastids (including chloroplasts) are subcellular sites for a plethora of proteolytic reactions, required in functions ranging from protein biogenesis to quality control. Here we show that peptides generated from pre-protein maturation within chloroplasts of Arabidopsis thaliana are degraded to amino acids by a multi-step peptidolytic cascade consisting of oligopeptidases and aminopeptidases, effectively allowing the recovery of single amino acids within these organelles.", "doi": "10.1038/nchembio.2227", "pmid": "27820795", "labels": {"Clinical Proteomics Mass spectrometry": "Collaborative", "Global Proteomics and Proteogenomics": "Collaborative", "Swedish Metabolomics Centre": "Service"}, "xrefs": [{"db": "pii", "key": "nchembio.2227"}], "notes": [], "created": "2017-05-03T12:59:39.078Z", "modified": "2025-10-17T13:03:19.180Z"}