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Gnann C, Cesnik AJ, Lundberg E
Trends Cancer 7 (4) 278-282 [2021-04-00; online 2021-01-10]
Cellular heterogeneity is an important biological phenomenon observed across space and time in human tissues. Imaging-based spatial proteomic technologies can provide fruitful new readouts of phenotypic states for individual cells at subcellular resolution, which may help unravel the roles of non-genetic cellular heterogeneity in tumorigenesis and drug resistance.
Spatial Proteomics [Technology development]
PubMed 33436349
DOI 10.1016/j.trecan.2020.12.006
Crossref 10.1016/j.trecan.2020.12.006
pii: S2405-8033(20)30333-2