Immunocyte single cell analysis of vaccine-induced narcolepsy.

Lind A, Salami F, Landtblom AM, Palm L, Lernmark Å, Adolfsson J, Elding Larsson H

Eur. J. Immunol. 51 (1) 247-249 [2021-01-00; online 2020-07-30]

Increased incidence of narcolepsy type 1 (NT1) was observed following Pandemrix®-vaccination, initiated as a preventive measure against the 2009 Influenza pandemic. Here, single cell analysis was conducted to suggest a lower number of CD8+ CD27+ T cells among these patients. These findings provide understanding into the autoimmune pathogenesis of NT1.

Cellular Immunomonitoring [Service]

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PubMed 32671842

DOI 10.1002/eji.202048633

Crossref 10.1002/eji.202048633