Targeted Chromosome Conformation Capture (HiCap).

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Zhigulev A, Sahlén P

Methods Mol. Biol. 2532 (-) 75-94 [2022-07-23; online 2022-07-23]

Targeted chromosome conformation capture (HiCap) is an experimental method for detecting spatial interactions of genomic features such as promoters and/or enhancers. The protocol first describes the design of sequence capture probes. After that, it provides details on the chromosome conformation capture adapted for next-generation sequencing (Hi-C). Finally, the methodology for coupling Hi-C with sequence capture technology is described.

NGI Short read [Service]

NGI Stockholm (Genomics Production) [Service]

National Genomics Infrastructure [Service]

PubMed 35867246

DOI 10.1007/978-1-0716-2497-5_5

Crossref 10.1007/978-1-0716-2497-5_5