Optimizing Solubility and Permeability of a Biopharmaceutics Classification System (BCS) Class 4 Antibiotic Drug Using Lipophilic Fragments Disturbing the Crystal Lattice

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Tehler U, Fagerberg JH, Svensson R, Larhed M, Artursson P, Bergström CAS

J. Med. Chem. 56 (6) 2690-2694 [2013-03-28; online 2013-03-28]

Chemical Biology Consortium Sweden (CBCS) [Technology development]

PubMed 23432334

DOI 10.1021/jm301721e

Crossref 10.1021/jm301721e