{"entity": "researcher", "timestamp": "2026-07-13T09:25:28.930Z", "family": "Stavrinidou", "given": "Eleni", "initials": "E", "orcid": "0000-0002-9357-776X", "affiliations": ["Laboratory of Organic Electronics, Department of Science and Technology, Link\u00f6ping University, Norrk\u00f6ping, SE-601 74, Sweden.", "Ume\u00e5 Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Ume\u00e5, 90183, Sweden.", "Wallenberg Wood Science Center, Department of Science and Technology, Link\u00f6ping University, Norrk\u00f6ping, SE-60174, Sweden."], "links": {"self": {"href": "https://publications.scilifelab.se/researcher/c311228cbcaa470ca772ab894000f45d.json"}, "display": {"href": "https://publications.scilifelab.se/researcher/c311228cbcaa470ca772ab894000f45d"}}, "publications": [{"entity": "publication", "iuid": "57c4b0adc568475fba8e61f5615175f8", "links": {"self": {"href": "https://publications.scilifelab.se/publication/57c4b0adc568475fba8e61f5615175f8.json"}, "display": {"href": "https://publications.scilifelab.se/publication/57c4b0adc568475fba8e61f5615175f8"}}, "title": "Glucose-Sensitive Biohybrid Roots for Supercapacitive Bioanodes.", "authors": [{"family": "Dufil", "given": "Gwenna\u00ebl", "initials": "G", "orcid": "0000-0001-5213-9002", "researcher": {"href": "https://publications.scilifelab.se/researcher/bc5e549e48be4fc6967987fb21d99ea5.json"}}, {"family": "Pham", "given": "Julie", "initials": "J"}, {"family": "Diacci", "given": "Chiara", "initials": "C"}, {"family": "Daguerre", "given": "Yohann", "initials": "Y"}, {"family": "Mantione", "given": "Daniele", "initials": "D", "orcid": "0000-0001-5495-9856", "researcher": {"href": "https://publications.scilifelab.se/researcher/cef165ee5ac34d5a8896d36867047878.json"}}, {"family": "Zrig", "given": "Samia", "initials": "S"}, {"family": "N\u00e4sholm", "given": "Torgny", "initials": "T"}, {"family": "Donahue", "given": "Mary J", "initials": "MJ"}, {"family": "Oikonomou", "given": "Vasileios K", "initials": "VK"}, {"family": "No\u00ebl", "given": "Vincent", "initials": "V", "orcid": "0000-0003-3901-8358", "researcher": {"href": "https://publications.scilifelab.se/researcher/75f6cd81202c4c20b2dd59ccfcc15f15.json"}}, {"family": "Piro", "given": "Benoit", "initials": "B"}, {"family": "Stavrinidou", "given": "Eleni", "initials": "E", "orcid": "0000-0002-9357-776X", "researcher": {"href": "https://publications.scilifelab.se/researcher/c311228cbcaa470ca772ab894000f45d.json"}}], "type": "journal article", "published": "2024-12-16", "journal": {"title": "ACS Appl Bio Mater", "issn": "2576-6422", "volume": "7", "issue": "12", "pages": "8632-8641", "issn-l": null}, "abstract": "Plants as living organisms, as well as their material-structural components and physiological processes, offer promising elements for developing more sustainable technologies. Previously, we demonstrated that plants could acquire electronic functionality, as their enzymatic activity catalyzes the in vivo polymerization of water-soluble conjugated oligomers. We then leveraged plant-integrated conductors to develop biohybrid energy storage devices and circuits. Here, we extend the concept of plant biohybrids to develop plant-based energy-harvesting devices. We demonstrate plant biohybrids with modified roots that can convert common root exudates, such as glucose, to electricity. To do so, we developed a simple one-step approach to convert living roots to glucose-sensitive electrodes by dipping the root in a solution of the conjugated trimer ETE-S and the enzyme glucose dehydrogenase flavin adenine dinucleotide. The biohybrid device responds to glucose concentrations down to 100 \u03bcM while it saturates at 100 mM. The performance of our approach was compared with a classic mediator-based glucose biosensor functionalization method. While the latter method increases the stability of the sensor, it results in less sensitivity and damages the root structure. Finally, we show that glucose oxidation can be combined with the volumetric capacitance of p(ETE-S)-forming devices that generate current in the presence of glucose and store it in the same biohybrid root electrodes. The plant biohybrid devices open a pathway to biologically integrated technology that finds application in low-power devices, for example, sensors for agriculture or the environment.", "doi": "10.1021/acsabm.4c01425", "pmid": "39625339", "labels": {"Swedish Metabolomics Centre": "Service"}, "xrefs": [{"db": "pmc", "key": "PMC11653237"}], "notes": [], "created": "2025-11-18T12:06:25.765Z", "modified": "2025-11-18T12:06:25.925Z"}, {"entity": "publication", "iuid": "5bae73c3a26a413b8e4db6f078c8c5a4", "links": {"self": {"href": "https://publications.scilifelab.se/publication/5bae73c3a26a413b8e4db6f078c8c5a4.json"}, "display": {"href": "https://publications.scilifelab.se/publication/5bae73c3a26a413b8e4db6f078c8c5a4"}}, "title": "Biohybrid Energy Storage Circuits Based on Electronically Functionalized Plant Roots.", "authors": [{"family": "Parker", "given": "Daniela", "initials": "D"}, {"family": "Dar", "given": "Abdul Manan", "initials": "AM"}, {"family": "Armada-Moreira", "given": "Adam", "initials": "A", "orcid": "0000-0002-1598-5784", "researcher": {"href": "https://publications.scilifelab.se/researcher/bcd30e8ddbc748df9bb5ff991173bd25.json"}}, {"family": "Bernacka Wojcik", "given": "Iwona", "initials": "I"}, {"family": "Rai", "given": "Rajat", "initials": "R", "orcid": "0000-0003-2175-0428", "researcher": {"href": "https://publications.scilifelab.se/researcher/845eb8a09d894df4868de22ef7937acb.json"}}, {"family": "Mantione", "given": "Daniele", "initials": "D", "orcid": "0000-0001-5495-9856", "researcher": {"href": "https://publications.scilifelab.se/researcher/cef165ee5ac34d5a8896d36867047878.json"}}, {"family": "Stavrinidou", "given": "Eleni", "initials": "E", "orcid": "0000-0002-9357-776X", "researcher": {"href": "https://publications.scilifelab.se/researcher/c311228cbcaa470ca772ab894000f45d.json"}}], "type": "journal article", "published": "2024-03-05", "journal": {"title": "ACS Appl Mater Interfaces", "issn": "1944-8252", "issn-l": "1944-8244"}, "abstract": "Biohybrid systems based on plants integrate plant structures and processes into technological components targeting more sustainable solutions. Plants' biocatalytic machinery, for example, has been leveraged for the organization of electronic materials directly in the vasculature and roots of living plants, resulting in biohybrid electrochemical devices. Among other applications, energy storage devices were demonstrated where the charge storage electrodes were seamlessly integrated into the plant tissue. However, the capacitance and the voltage output of a single biohybrid supercapacitor are limited. Here, we developed biohybrid circuits based on functionalized conducting roots, extending the performance of plant based biohybrid energy storage systems. We show that root-supercapacitors can be combined in series and in parallel configuration, achieving up to 1.5 V voltage output or up to 11 mF capacitance, respectively. We further demonstrate that the supercapacitors circuit can be charged with an organic photovoltaic cell, and that the stored charge can be used to power an electrochromic display or a bioelectronic device. Furthermore, the functionalized roots degrade in composting similarly to native roots. The proof-of-concept demonstrations illustrate the potential of this technology to achieve more sustainable solutions for powering low consumption devices such as bioelectronics for agriculture or IoT applications.", "doi": "10.1021/acsami.3c16861", "pmid": "38441544", "labels": {"Integrated Microscopy Technologies Ume\u00e5": "Service", "Cryo-EM": "Service"}, "xrefs": [], "notes": [], "created": "2024-11-13T12:53:50.143Z", "modified": "2024-11-13T12:53:50.718Z"}, {"entity": "publication", "iuid": "dc94714c2f924302bdaa51c3ba01d9da", "links": {"self": {"href": "https://publications.scilifelab.se/publication/dc94714c2f924302bdaa51c3ba01d9da.json"}, "display": {"href": "https://publications.scilifelab.se/publication/dc94714c2f924302bdaa51c3ba01d9da"}}, "title": "Flexible Organic Electronic Ion Pump for Flow-Free Phytohormone Delivery into Vasculature of Intact Plants.", "authors": [{"family": "Bernacka-Wojcik", "given": "Iwona", "initials": "I", "orcid": "0000-0002-7135-8275", "researcher": {"href": "https://publications.scilifelab.se/researcher/393624af38a04a6fa724f1d4f33cf0e6.json"}}, {"family": "Talide", "given": "Lo\u00efc", "initials": "L"}, {"family": "Abdel Aziz", "given": "Ilaria", "initials": "I"}, {"family": "Simura", "given": "Jan", "initials": "J"}, {"family": "Oikonomou", "given": "Vasileios K", "initials": "VK"}, {"family": "Rossi", "given": "Stefano", "initials": "S"}, {"family": "Mohammadi", "given": "Mohsen", "initials": "M"}, {"family": "Dar", "given": "Abdul Manan", "initials": "AM"}, {"family": "Seitanidou", "given": "Maria", "initials": "M"}, {"family": "Berggren", "given": "Magnus", "initials": "M"}, {"family": "Simon", "given": "Daniel T", "initials": "DT"}, {"family": "Tybrandt", "given": "Klas", "initials": "K"}, {"family": "Jonsson", "given": "Magnus P", "initials": "MP"}, {"family": "Ljung", "given": "Karin", "initials": "K"}, {"family": "Niittyl\u00e4", "given": "Totte", "initials": "T"}, {"family": "Stavrinidou", "given": "Eleni", "initials": "E", "orcid": "0000-0002-9357-776X", "researcher": {"href": "https://publications.scilifelab.se/researcher/c311228cbcaa470ca772ab894000f45d.json"}}], "type": "journal article", "published": "2023-05-00", "journal": {"title": "Adv Sci (Weinh)", "issn": "2198-3844", "volume": "10", "issue": "14", "pages": "e2206409", "issn-l": null}, "abstract": "Plant vasculature transports molecules that play a crucial role in plant signaling including systemic responses and acclimation to diverse environmental conditions. Targeted controlled delivery of molecules to the vascular tissue can be a biomimetic way to induce long distance responses, providing a new tool for the fundamental studies and engineering of stress-tolerant plants. Here, a flexible organic electronic ion pump, an electrophoretic delivery device, for controlled delivery of phytohormones directly in plant vascular tissue is developed. The c-OEIP is based on polyimide-coated glass capillaries that significantly enhance the mechanical robustness of these microscale devices while being minimally disruptive for the plant. The polyelectrolyte channel is based on low-cost and commercially available precursors that can be photocured with blue light, establishing much cheaper and safer system than the state-of-the-art. To trigger OEIP-induced plant response, the phytohormone abscisic acid (ABA) in the petiole of intact Arabidopsis plants is delivered. ABA is one of the main phytohormones involved in plant stress responses and induces stomata closure under drought conditions to reduce water loss and prevent wilting. The OEIP-mediated ABA delivery triggered fast and long-lasting stomata closure far away from the delivery point demonstrating systemic vascular transport of the delivered ABA, verified delivering deuterium-labeled ABA.", "doi": "10.1002/advs.202206409", "pmid": "36935365", "labels": {"Swedish Metabolomics Centre": "Service"}, "xrefs": [{"db": "pmc", "key": "PMC10190655"}], "notes": [], "created": "2023-08-30T07:04:28.312Z", "modified": "2025-10-17T13:03:13.982Z"}, {"entity": "publication", "iuid": "cf82395f3a744a54a1a0fa1f79e343c4", "links": {"self": {"href": "https://publications.scilifelab.se/publication/cf82395f3a744a54a1a0fa1f79e343c4.json"}, "display": {"href": "https://publications.scilifelab.se/publication/cf82395f3a744a54a1a0fa1f79e343c4"}}, "title": "Chitosan-Modified Polyethyleneimine Nanoparticles for Enhancing the Carboxylation Reaction and Plants' CO2 Uptake.", "authors": [{"family": "Routier", "given": "Cyril", "initials": "C"}, {"family": "Vallan", "given": "Lorenzo", "initials": "L", "orcid": "0000-0001-5267-4849", "researcher": {"href": "https://publications.scilifelab.se/researcher/380013a04644414ba84ed361712da42b.json"}}, {"family": "Daguerre", "given": "Yohann", "initials": "Y"}, {"family": "Juvany", "given": "Marta", "initials": "M"}, {"family": "Istif", "given": "Emin", "initials": "E"}, {"family": "Mantione", "given": "Daniele", "initials": "D"}, {"family": "Brochon", "given": "Cyril", "initials": "C", "orcid": "0000-0003-3242-1574", "researcher": {"href": "https://publications.scilifelab.se/researcher/b0ac7c32b919447db8232b7f2c6f7f21.json"}}, {"family": "Hadziioannou", "given": "Georges", "initials": "G", "orcid": "0000-0002-7377-6040", "researcher": {"href": "https://publications.scilifelab.se/researcher/f37fd38ddc554a2b9c30fd9a8be86197.json"}}, {"family": "Strand", "given": "\u00c5sa", "initials": "\u00c5"}, {"family": "N\u00e4sholm", "given": "Torgny", "initials": "T"}, {"family": "Cloutet", "given": "Eric", "initials": "E"}, {"family": "Pavlopoulou", "given": "Eleni", "initials": "E", "orcid": "0000-0002-5291-0132", "researcher": {"href": "https://publications.scilifelab.se/researcher/8fe58aab0eee47e59eeb4a3e20393001.json"}}, {"family": "Stavrinidou", "given": "Eleni", "initials": "E", "orcid": "0000-0002-9357-776X", "researcher": {"href": "https://publications.scilifelab.se/researcher/c311228cbcaa470ca772ab894000f45d.json"}}], "type": "journal article", "published": "2023-02-28", "journal": {"title": "ACS Nano", "issn": "1936-086X", "issn-l": "1936-0851", "volume": "17", "issue": "4", "pages": "3430-3441"}, "abstract": "Increasing plants' photosynthetic efficiency is a major challenge that must be addressed in order to cover the food demands of the growing population in the changing climate. Photosynthesis is greatly limited at the initial carboxylation reaction, where CO2 is converted to the organic acid 3-PGA, catalyzed by the RuBisCO enzyme. RuBisCO has poor affinity for CO2, but also the CO2 concentration at the RuBisCO site is limited by the diffusion of atmospheric CO2 through the various leaf compartments to the reaction site. Beyond genetic engineering, nanotechnology can offer a materials-based approach for enhancing photosynthesis, and yet, it has mostly been explored for the light-dependent reactions. In this work, we developed polyethyleneimine-based nanoparticles for enhancing the carboxylation reaction. We demonstrate that the nanoparticles can capture CO2 in the form of bicarbonate and increase the CO2 that reacts with the RuBisCO enzyme, enhancing the 3-PGA production in in vitro assays by 20%. The nanoparticles can be introduced to the plant via leaf infiltration and, because of the functionalization with chitosan oligomers, they do not induce any toxic effect to the plant. In the leaves, the nanoparticles localize in the apoplastic space but also spontaneously reach the chloroplasts where photosynthetic activity takes place. Their CO2 loading-dependent fluorescence verifies that, in vivo, they maintain their ability to capture CO2 and can be therefore reloaded with atmospheric CO2 while in planta. Our results contribute to the development of a nanomaterials-based CO2-concentrating mechanism in plants that can potentially increase photosynthetic efficiency and overall plants' CO2 storage.", "doi": "10.1021/acsnano.2c09255", "pmid": "36796108", "labels": {"Swedish Metabolomics Centre": "Collaborative"}, "xrefs": [{"db": "pmc", "key": "PMC9979637"}], "notes": [], "created": "2023-08-30T07:04:30.967Z", "modified": "2025-10-17T13:03:14.183Z"}]}