{"entity": "researcher", "timestamp": "2026-06-15T08:53:58.997Z", "family": "Ziarelli", "given": "Fabio", "initials": "F", "orcid": "0000-0002-0050-9689", "affiliations": ["Aix Marseille Univ, CNRS, Centrale Marseille, FSCM Marseille France."], "links": {"self": {"href": "https://publications.scilifelab.se/researcher/c147dce214364d62b7cb54bfac76e1ed.json"}, "display": {"href": "https://publications.scilifelab.se/researcher/c147dce214364d62b7cb54bfac76e1ed"}}, "publications": [{"entity": "publication", "iuid": "ae443400124646abbbafbf6c3df9f43b", "links": {"self": {"href": "https://publications.scilifelab.se/publication/ae443400124646abbbafbf6c3df9f43b.json"}, "display": {"href": "https://publications.scilifelab.se/publication/ae443400124646abbbafbf6c3df9f43b"}}, "title": "Exploiting solid-state dynamic nuclear polarization NMR spectroscopy to establish the spatial distribution of polymorphic phases in a solid material.", "authors": [{"family": "Cousin", "given": "Samuel F", "initials": "SF", "orcid": "0000-0002-7021-478X", "researcher": {"href": "https://publications.scilifelab.se/researcher/696aced06abd460a8fc78514eadb659f.json"}}, {"family": "Hughes", "given": "Colan E", "initials": "CE", "orcid": "0000-0003-2374-2763", "researcher": {"href": "https://publications.scilifelab.se/researcher/e0cab13b3a8347a2a75b56c57e3a498f.json"}}, {"family": "Ziarelli", "given": "Fabio", "initials": "F", "orcid": "0000-0002-0050-9689", "researcher": {"href": "https://publications.scilifelab.se/researcher/c147dce214364d62b7cb54bfac76e1ed.json"}}, {"family": "Viel", "given": "St\u00e9phane", "initials": "S", "orcid": "0000-0003-3338-0559", "researcher": {"href": "https://publications.scilifelab.se/researcher/02e5816cb2cc4f1f9622ec6aaeae622c.json"}}, {"family": "Mollica", "given": "Giulia", "initials": "G", "orcid": "0000-0002-6896-2447", "researcher": {"href": "https://publications.scilifelab.se/researcher/0679a5f1a9124fa2bbc81710b0db15e4.json"}}, {"family": "Harris", "given": "Kenneth D M", "initials": "KDM", "orcid": "0000-0001-7855-8598", "researcher": {"href": "https://publications.scilifelab.se/researcher/9f795cff838d43e6a5e6fb00397f117c.json"}}, {"family": "Pinon", "given": "Arthur C", "initials": "AC"}, {"family": "Thureau", "given": "Pierre", "initials": "P", "orcid": "0000-0002-9157-256X", "researcher": {"href": "https://publications.scilifelab.se/researcher/b2fff75e225b40cbb06e7790b8b91195.json"}}], "type": "journal article", "published": "2023-09-27", "journal": {"title": "Chem. Sci.", "issn": "2041-6520", "volume": "14", "issue": "37", "pages": "10121-10128", "issn-l": null}, "abstract": "Solid-state DNP NMR can enhance the ability to detect minor amounts of solid phases within heterogenous materials. Here we demonstrate that NMR contrast based on the transport of DNP-enhanced polarization can be exploited in the challenging case of early detection of a small amount of a minor polymorphic phase within a major polymorph, and we show that this approach can yield quantitative information on the spatial distribution of the two polymorphs. We focus on the detection of a minor amount (<4%) of polymorph III of m-aminobenzoic acid within a powder sample of polymorph I at natural isotopic abundance. Based on proposed models of the spatial distribution of the two polymorphs, simulations of 1H spin diffusion allow NMR data to be calculated for each model as a function of particle size and the relative amounts of the polymorphs. A comparison between simulated and experimental NMR data allows the model(s) best representing the spatial distribution of the polymorphs in the system to be established.", "doi": "10.1039/d3sc02063k", "pmid": "37772100", "labels": {"Swedish NMR Centre": "Technology development"}, "xrefs": [{"db": "pmc", "key": "PMC10530703"}, {"db": "pii", "key": "d3sc02063k"}], "notes": [], "created": "2023-12-04T09:35:44.066Z", "modified": "2025-10-17T13:03:53.501Z"}]}