{"entity": "researcher", "timestamp": "2026-04-16T17:57:30.181Z", "family": "While", "given": "Geoffrey M", "initials": "GM", "orcid": "0000-0001-8122-9322", "affiliations": ["School of Natural Sciences, University of Tasmania, Sandy Bay, Tasmania, Australia."], "links": {"self": {"href": "https://publications.scilifelab.se/researcher/b40ba32f8185473fa3543815e8a539fe.json"}, "display": {"href": "https://publications.scilifelab.se/researcher/b40ba32f8185473fa3543815e8a539fe"}}, "publications": [{"entity": "publication", "iuid": "7d3c4336130e450099e81cfa741064ec", "links": {"self": {"href": "https://publications.scilifelab.se/publication/7d3c4336130e450099e81cfa741064ec.json"}, "display": {"href": "https://publications.scilifelab.se/publication/7d3c4336130e450099e81cfa741064ec"}}, "title": "Adaptive introgression reveals the genetic basis of a sexually selected syndrome in wall lizards.", "authors": [{"family": "Feiner", "given": "Nathalie", "initials": "N", "orcid": "0000-0003-4648-6950", "researcher": {"href": "https://publications.scilifelab.se/researcher/4dfa523d52b348359775994be5d69640.json"}}, {"family": "Yang", "given": "Weizhao", "initials": "W"}, {"family": "Bunikis", "given": "Ignas", "initials": "I"}, {"family": "While", "given": "Geoffrey M", "initials": "GM", "orcid": "0000-0001-8122-9322", "researcher": {"href": "https://publications.scilifelab.se/researcher/b40ba32f8185473fa3543815e8a539fe.json"}}, {"family": "Uller", "given": "Tobias", "initials": "T", "orcid": "0000-0003-1293-5842", "researcher": {"href": "https://publications.scilifelab.se/researcher/6346267a5c3e41c6a6825b7b20a53fa5.json"}}], "type": "journal article", "published": "2024-04-05", "journal": {"title": "Sci Adv", "issn": "2375-2548", "volume": "10", "issue": "14", "pages": "eadk9315", "issn-l": "2375-2548"}, "abstract": "The joint expression of particular colors, morphologies, and behaviors is a common feature of adaptation, but the genetic basis for such \"phenotypic syndromes\" remains poorly understood. Here, we identified a complex genetic architecture associated with a sexually selected syndrome in common wall lizards, by capitalizing on the adaptive introgression of coloration and morphology into a distantly related lineage. Consistent with the hypothesis that the evolution of phenotypic syndromes in vertebrates is facilitated by developmental linkage through neural crest cells, most of the genes associated with the syndrome are involved in neural crest cell regulation. A major locus was a ~400-kb region, characterized by standing structural genetic variation and previously implied in the evolutionary innovation of coloration and beak size in birds. We conclude that features of the developmental and genetic architecture contribute to maintaining trait integration, facilitating the extensive and rapid introgressive spread of suites of sexually selected characters.", "doi": "10.1126/sciadv.adk9315", "pmid": "38569035", "labels": {"NGI Stockholm (Genomics Production)": "Service", "NGI Stockholm (Genomics Applications)": "Service", "National Genomics Infrastructure": "Collaborative", "NGI Uppsala (Uppsala Genome Center)": "Collaborative", "NGI Long read": "Collaborative", "Bioinformatics Support for Computational Resources": "Service"}, "xrefs": [{"db": "pmc", "key": "PMC10990284"}], "notes": [], "created": "2024-04-09T12:41:11.047Z", "modified": "2024-11-25T10:28:12.121Z"}]}