{"entity": "researcher", "timestamp": "2026-08-08T15:57:20.351Z", "family": "Teixeira", "given": "Pedro F", "initials": "PF", "orcid": "0000-0001-8638-7477", "affiliations": ["Department of Biochemistry and Biophysics, Stockholm University, Arrhenius Laboratories for Natural Sciences, Stockholm SE-106 91, Sweden."], "links": {"self": {"href": "https://publications.scilifelab.se/researcher/9b43730fe20b424db84f091333be7244.json"}, "display": {"href": "https://publications.scilifelab.se/researcher/9b43730fe20b424db84f091333be7244"}}, "publications": [{"entity": "publication", "iuid": "170fec648fb448e99fbe3bd024cd7e34", "links": {"self": {"href": "https://publications.scilifelab.se/publication/170fec648fb448e99fbe3bd024cd7e34.json"}, "display": {"href": "https://publications.scilifelab.se/publication/170fec648fb448e99fbe3bd024cd7e34"}}, "title": "A Mitochondrial LYR Protein Is Required for Complex I Assembly.", "authors": [{"family": "Ivanova", "given": "Aneta", "initials": "A", "orcid": "0000-0002-2465-7213", "researcher": {"href": "https://publications.scilifelab.se/researcher/3b4791ef8f5843949894df534ff8355e.json"}}, {"family": "Gill-Hille", "given": "Mabel", "initials": "M", "orcid": "0000-0001-7749-5839", "researcher": {"href": "https://publications.scilifelab.se/researcher/7eb758e47fb34b8a86f076d1574c31b1.json"}}, {"family": "Huang", "given": "Shaobai", "initials": "S", "orcid": "0000-0003-3667-611X", "researcher": {"href": "https://publications.scilifelab.se/researcher/eee12c8a03254793b1735eb4510fc90f.json"}}, {"family": "Branca", "given": "Rui M", "initials": "RM", "orcid": "0000-0003-3890-6476", "researcher": {"href": "https://publications.scilifelab.se/researcher/87d6256540174d3da581d4572f9d182a.json"}}, {"family": "Kmiec", "given": "Beata", "initials": "B", "orcid": "0000-0002-1383-0412", "researcher": {"href": "https://publications.scilifelab.se/researcher/7cacde5eab9a4ce8ada537324ed66d05.json"}}, {"family": "Teixeira", "given": "Pedro F", "initials": "PF", "orcid": "0000-0001-8638-7477", "researcher": {"href": "https://publications.scilifelab.se/researcher/9b43730fe20b424db84f091333be7244.json"}}, {"family": "Lehti\u00f6", "given": "Janne", "initials": "J", "orcid": "0000-0002-8100-9562", "researcher": {"href": "https://publications.scilifelab.se/researcher/8406a97bac744a59b1bc951978994581.json"}}, {"family": "Whelan", "given": "James", "initials": "J", "orcid": "0000-0001-5754-025X", "researcher": {"href": "https://publications.scilifelab.se/researcher/15d6dae558a24c03b6298dc9bd5b991d.json"}}, {"family": "Murcha", "given": "Monika W", "initials": "MW", "orcid": "0000-0002-3689-6158", "researcher": {"href": "https://publications.scilifelab.se/researcher/49b1e7e1fca74be090072ad2185c9827.json"}}], "type": "journal article", "published": "2019-12-00", "journal": {"volume": "181", "issn": "1532-2548", "issue": "4", "pages": "1632-1650", "title": "Plant Physiol.", "issn-l": "0032-0889"}, "abstract": "Complex I biogenesis requires the expression of both nuclear and mitochondrial genes, the import of proteins, cofactor biosynthesis, and the assembly of at least 49 individual subunits. Assembly factors interact with subunits of Complex I but are not part of the final holocomplex. We show that in Arabidopsis (Arabidopsis thaliana), a mitochondrial matrix protein (EMB1793, At1g76060), which we term COMPLEX I ASSEMBLY FACTOR 1 (CIAF1), contains a LYR domain and is required for Complex I assembly. T-DNA insertion mutants of CIAF1 lack Complex I and the Supercomplex I+III. Biochemical characterization shows that the assembly of Complex I is stalled at 650 and 800 kD intermediates in mitochondria isolated from ciaf1 mutant lines.I. Yeast-two-hybrid interaction and complementation assays indicate that CIAF1 specifically interacts with the 23-kD TYKY-1 matrix domain subunit of Complex I and likely plays a role in Fe-S insertion into this subunit. These data show that CIAF1 plays an essential role in assembling the peripheral matrix arm Complex I subunits into the Complex I holoenzyme.", "doi": "10.1104/pp.19.00822", "pmid": "31601645", "labels": {"Global Proteomics and Proteogenomics": "Collaborative"}, "xrefs": [{"db": "pii", "key": "pp.19.00822"}, {"db": "pmc", "key": "PMC6878026"}], "notes": [], "created": "2020-01-07T12:28:27.281Z", "modified": "2021-07-08T11:16:55.122Z"}, {"entity": "publication", "iuid": "37442ab98d914bb1827ce6b803dae200", "links": {"self": {"href": "https://publications.scilifelab.se/publication/37442ab98d914bb1827ce6b803dae200.json"}, "display": {"href": "https://publications.scilifelab.se/publication/37442ab98d914bb1827ce6b803dae200"}}, "title": "A multi-step peptidolytic cascade for amino acid recovery in chloroplasts.", "authors": [{"family": "Teixeira", "given": "Pedro F", "initials": "PF", "orcid": "0000-0001-8638-7477", "researcher": {"href": "https://publications.scilifelab.se/researcher/9b43730fe20b424db84f091333be7244.json"}}, {"family": "Kmiec", "given": "Beata", "initials": "B"}, {"family": "Branca", "given": "Rui M M", "initials": "RM"}, {"family": "Murcha", "given": "Monika W", "initials": "MW", "orcid": "0000-0002-3689-6158", "researcher": {"href": "https://publications.scilifelab.se/researcher/49b1e7e1fca74be090072ad2185c9827.json"}}, {"family": "Byzia", "given": "Anna", "initials": "A"}, {"family": "Ivanova", "given": "Aneta", "initials": "A"}, {"family": "Whelan", "given": "James", "initials": "J"}, {"family": "Drag", "given": "Marcin", "initials": "M"}, {"family": "Lehti\u00f6", "given": "Janne", "initials": "J", "orcid": "0000-0002-8100-9562", "researcher": {"href": "https://publications.scilifelab.se/researcher/8406a97bac744a59b1bc951978994581.json"}}, {"family": "Glaser", "given": "Elzbieta", "initials": "E"}], "type": "journal article", "published": "2017-01-00", "journal": {"volume": "13", "issn": "1552-4469", "issue": "1", "pages": "15-17", "title": "Nat. Chem. Biol.", "issn-l": "1552-4450"}, "abstract": "Plastids (including chloroplasts) are subcellular sites for a plethora of proteolytic reactions, required in functions ranging from protein biogenesis to quality control. Here we show that peptides generated from pre-protein maturation within chloroplasts of Arabidopsis thaliana are degraded to amino acids by a multi-step peptidolytic cascade consisting of oligopeptidases and aminopeptidases, effectively allowing the recovery of single amino acids within these organelles.", "doi": "10.1038/nchembio.2227", "pmid": "27820795", "labels": {"Clinical Proteomics Mass spectrometry": "Collaborative", "Global Proteomics and Proteogenomics": "Collaborative", "Swedish Metabolomics Centre": "Service"}, "xrefs": [{"db": "pii", "key": "nchembio.2227"}], "notes": [], "created": "2017-05-03T12:59:39.078Z", "modified": "2025-10-17T13:03:19.180Z"}]}