{"entity": "researcher", "timestamp": "2026-06-08T05:00:08.718Z", "family": "Wellenreuther", "given": "Maren", "initials": "M", "orcid": "0000-0002-2764-8291", "affiliations": ["The New Zealand Institute for Plant and Food Research Ltd, Nelson, New Zealand.", "School of Biological Sciences, University of Auckland, Auckland, New Zealand."], "links": {"self": {"href": "https://publications.scilifelab.se/researcher/82e9b593bf0f4535a7b9231608b1e27d.json"}, "display": {"href": "https://publications.scilifelab.se/researcher/82e9b593bf0f4535a7b9231608b1e27d"}}, "publications": [{"entity": "publication", "iuid": "383fc2f557f74c5ca9961f9823a9c2e0", "links": {"self": {"href": "https://publications.scilifelab.se/publication/383fc2f557f74c5ca9961f9823a9c2e0.json"}, "display": {"href": "https://publications.scilifelab.se/publication/383fc2f557f74c5ca9961f9823a9c2e0"}}, "title": "Parallel clines of chromosomal inversion frequencies in seaweed flies are associated with thermal variation.", "authors": [{"family": "Nicolas", "given": "L\u00e9a A", "initials": "LA", "orcid": "0009-0007-2292-8431", "researcher": {"href": "https://publications.scilifelab.se/researcher/400196db3fb04ab0911f28029b922598.json"}}, {"family": "Berdan", "given": "Emma L", "initials": "EL", "orcid": "0000-0002-6435-4604", "researcher": {"href": "https://publications.scilifelab.se/researcher/9f65066e9a744b95b25ec0597b4b8e23.json"}}, {"family": "Wellenreuther", "given": "Maren", "initials": "M", "orcid": "0000-0002-2764-8291", "researcher": {"href": "https://publications.scilifelab.se/researcher/82e9b593bf0f4535a7b9231608b1e27d.json"}}, {"family": "Colinet", "given": "Herv\u00e9", "initials": "H"}, {"family": "Clouard", "given": "Andr\u00e9a", "initials": "A"}, {"family": "De Wit", "given": "Pierre", "initials": "P", "orcid": "0000-0003-4709-3438", "researcher": {"href": "https://publications.scilifelab.se/researcher/95b69d4724ce4b69819c0a1578cd56eb.json"}}, {"family": "Gl\u00e9min", "given": "Sylvain", "initials": "S"}, {"family": "M\u00e9rot", "given": "Claire", "initials": "C"}], "type": "journal article", "published": "2025-11-05", "journal": {"title": "Heredity (Edinb)", "issn": "1365-2540", "issn-l": "0018-067X"}, "abstract": "Chromosomal inversion supergenes, which form blocks of linked genes, are increasingly recognized for their role in maintaining intra-specific diversity. They are predicted to be relevant genetic architectures for local adaptation in the face of gene flow. However, pinpointing the underlying traits and functional mechanisms under selection remains challenging. The seaweed fly Coelopa frigida harbors several large polymorphic inversions, of which the Cf-Inv(4.1) inversion displays a latitudinal cline of frequencies along the North American Atlantic Coast, suggesting a putative role in adaptation along the eco-climatic gradient. To investigate this hypothesis, we designed a molecular marker for karyotyping and studied natural and experimental populations from North America and Europe. We confirmed that this inversion is also polymorphic in Europe, and displays parallel latitudinal clines across continents, providing strong indirect support that Cf-Inv(4.1) is under natural selection along similar environmental gradients. We found that Cf-Inv(4.1) had a significant impact on egg-to-adult survival and fecundity under different thermal conditions. However, no effect on cold tolerance could be determined using supercooling point and chill coma recovery time. We speculate that fitness associated with Cf-Inv(4.1) is shaped by subtle life-history differences whose relative advantage depends on climate. While our experimental approaches provided insights into genotype-phenotype associations, it is worth noting that selection acts on the overall fitness, involving complex sets of traits. This is especially relevant for inversions linking hundreds of genes. This multi-gene property also explains why inversions are frequently involved in repeated parallel adaptation to environmental gradients, as demonstrated here in the seaweed fly.", "doi": "10.1038/s41437-025-00808-3", "pmid": "41193615", "labels": {"National Genomics Infrastructure": "Service", "NGI Stockholm (Genomics Production)": "Service", "NGI Short read": "Service"}, "xrefs": [{"db": "pii", "key": "10.1038/s41437-025-00808-3"}], "notes": [], "created": "2025-11-19T07:41:34.155Z", "modified": "2025-11-19T07:41:34.300Z"}, {"entity": "publication", "iuid": "796f460ce9794c089a8bdd175c3a9b65", "links": {"self": {"href": "https://publications.scilifelab.se/publication/796f460ce9794c089a8bdd175c3a9b65.json"}, "display": {"href": "https://publications.scilifelab.se/publication/796f460ce9794c089a8bdd175c3a9b65"}}, "title": "Restricted X chromosome introgression and support for Haldane's rule in hybridizing damselflies.", "authors": [{"family": "Swaegers", "given": "Janne", "initials": "J", "orcid": "0000-0003-1952-3170", "researcher": {"href": "https://publications.scilifelab.se/researcher/0cb5191ea7e94e8696e42fc15e854ce8.json"}}, {"family": "S\u00e1nchez-Guill\u00e9n", "given": "Rosa Ana", "initials": "RA", "orcid": "0000-0001-6024-8321", "researcher": {"href": "https://publications.scilifelab.se/researcher/c03f95fe4ced4dd690950ab8bb656710.json"}}, {"family": "Chauhan", "given": "Pallavi", "initials": "P", "orcid": "0000-0002-5160-6673", "researcher": {"href": "https://publications.scilifelab.se/researcher/c2ca3733447d4e38ae5cce50d1b4d165.json"}}, {"family": "Wellenreuther", "given": "Maren", "initials": "M", "orcid": "0000-0002-2764-8291", "researcher": {"href": "https://publications.scilifelab.se/researcher/82e9b593bf0f4535a7b9231608b1e27d.json"}}, {"family": "Hansson", "given": "Bengt", "initials": "B", "orcid": "0000-0001-6694-8169", "researcher": {"href": "https://publications.scilifelab.se/researcher/01f0144e207c41dcbc4d5aec68690e4b.json"}}], "type": "journal article", "published": "2022-07-27", "journal": {"title": "Proc. Biol. Sci.", "issn": "1471-2954", "issn-l": "0962-8452", "volume": "289", "issue": "1979", "pages": "20220968"}, "abstract": "Contemporary hybrid zones act as natural laboratories for the investigation of species boundaries and may shed light on the little understood roles of sex chromosomes in species divergence. Sex chromosomes are considered to function as a hotspot of genetic divergence between species; indicated by less genomic introgression compared to autosomes during hybridization. Moreover, they are thought to contribute to Haldane's rule, which states that hybrids of the heterogametic sex are more likely to be inviable or sterile. To test these hypotheses, we used contemporary hybrid zones of Ischnura elegans, a damselfly species that has been expanding its range into the northern and western regions of Spain, leading to chronic hybridization with its sister species Ischnura graellsii. We analysed genome-wide SNPs in the Spanish I. elegans and I. graellsii hybrid zone and found (i) that the X chromosome shows less genomic introgression compared to autosomes, and (ii) that males are underrepresented among admixed individuals, as predicted by Haldane's rule. This is the first study in Odonata that suggests a role of the X chromosome in reproductive isolation. Moreover, our data add to the few studies on species with X0 sex determination system and contradict the hypothesis that the absence of a Y chromosome causes exceptions to Haldane's rule.", "doi": "10.1098/rspb.2022.0968", "pmid": "35855603", "labels": {"NGI Short read": "Service", "NGI Uppsala (SNP&SEQ Technology Platform)": "Service", "National Genomics Infrastructure": "Service", "Bioinformatics Support for Computational Resources": "Service"}, "xrefs": [{"db": "pmc", "key": "PMC9297008"}, {"db": "Dryad", "key": "10.5061/dryad.gqnk98sp8"}], "notes": [], "created": "2022-11-09T15:50:07.860Z", "modified": "2024-01-16T13:48:35.646Z"}]}