{"entity": "researcher", "timestamp": "2026-08-15T22:21:25.213Z", "family": "Busch", "given": "Wolfgang", "initials": "W", "orcid": "0000-0003-2042-7290", "affiliations": [], "links": {"self": {"href": "https://publications.scilifelab.se/researcher/690f19002a5e49aea937eb9025827fae.json"}, "display": {"href": "https://publications.scilifelab.se/researcher/690f19002a5e49aea937eb9025827fae"}}, "publications": [{"entity": "publication", "iuid": "796d298838e14da89a5adb267514aac4", "links": {"self": {"href": "https://publications.scilifelab.se/publication/796d298838e14da89a5adb267514aac4.json"}, "display": {"href": "https://publications.scilifelab.se/publication/796d298838e14da89a5adb267514aac4"}}, "title": "HY5 and phytochrome activity modulate shoot-to-root coordination during thermomorphogenesis in Arabidopsis.", "authors": [{"family": "Gaillochet", "given": "Christophe", "initials": "C"}, {"family": "Burko", "given": "Yogev", "initials": "Y"}, {"family": "Platre", "given": "Matthieu Pierre", "initials": "MP", "orcid": "0000-0002-4934-3050", "researcher": {"href": "https://publications.scilifelab.se/researcher/7fb4dfd55aae43db8a082ca3b2e4d0e0.json"}}, {"family": "Zhang", "given": "Ling", "initials": "L"}, {"family": "Simura", "given": "Jan", "initials": "J"}, {"family": "Willige", "given": "Bj\u00f6rn C", "initials": "BC", "orcid": "0000-0003-4275-5826", "researcher": {"href": "https://publications.scilifelab.se/researcher/92cf9ec5b382449c9c4474b2e5b9e915.json"}}, {"family": "Kumar", "given": "S Vinod", "initials": "SV"}, {"family": "Ljung", "given": "Karin", "initials": "K"}, {"family": "Chory", "given": "Joanne", "initials": "J"}, {"family": "Busch", "given": "Wolfgang", "initials": "W", "orcid": "0000-0003-2042-7290", "researcher": {"href": "https://publications.scilifelab.se/researcher/690f19002a5e49aea937eb9025827fae.json"}}], "type": "journal article", "published": "2020-12-15", "journal": {"title": "Development", "issn": "1477-9129", "volume": "147", "issue": "24", "issn-l": "0950-1991"}, "abstract": "Temperature is one of the most impactful environmental factors to which plants adjust their growth and development. Although the regulation of temperature signaling has been extensively investigated for the aerial part of plants, much less is known and understood about how roots sense and modulate their growth in response to fluctuating temperatures. Here, we found that shoot and root growth responses to high ambient temperature are coordinated during early seedling development in Arabidopsis A shoot signaling module that includes HY5, the phytochromes and the PIFs exerts a central function in coupling these growth responses and maintaining auxin levels in the root. In addition to the HY5/PIF-dependent shoot module, a regulatory axis composed of auxin biosynthesis and auxin perception factors controls root responses to high ambient temperature. Taken together, our findings show that shoot and root developmental responses to temperature are tightly coupled during thermomorphogenesis and suggest that roots integrate energy signals with local hormonal inputs.", "doi": "10.1242/dev.192625", "pmid": "33144393", "labels": {"Swedish Metabolomics Centre": "Service"}, "xrefs": [{"db": "pmc", "key": "PMC7758624"}, {"db": "pii", "key": "226051"}], "notes": [], "created": "2023-04-12T14:19:44.787Z", "modified": "2025-10-17T13:03:16.496Z"}, {"entity": "publication", "iuid": "4f6a27020d4e4cc8a66101b05df1d17e", "links": {"self": {"href": "https://publications.scilifelab.se/publication/4f6a27020d4e4cc8a66101b05df1d17e.json"}, "display": {"href": "https://publications.scilifelab.se/publication/4f6a27020d4e4cc8a66101b05df1d17e"}}, "title": "Auxin minimum triggers the developmental switch from cell division to cell differentiation in the Arabidopsis root.", "authors": [{"family": "Di Mambro", "given": "Riccardo", "initials": "R", "orcid": "0000-0002-1243-7395", "researcher": {"href": "https://publications.scilifelab.se/researcher/e06682ddf24e45648d08dc1db5a272d5.json"}}, {"family": "De Ruvo", "given": "Micol", "initials": "M"}, {"family": "Pacifici", "given": "Elena", "initials": "E"}, {"family": "Salvi", "given": "Elena", "initials": "E"}, {"family": "Sozzani", "given": "Rosangela", "initials": "R"}, {"family": "Benfey", "given": "Philip N", "initials": "PN"}, {"family": "Busch", "given": "Wolfgang", "initials": "W", "orcid": "0000-0003-2042-7290", "researcher": {"href": "https://publications.scilifelab.se/researcher/690f19002a5e49aea937eb9025827fae.json"}}, {"family": "Novak", "given": "Ondrej", "initials": "O", "orcid": "0000-0003-3452-0154", "researcher": {"href": "https://publications.scilifelab.se/researcher/8c19165acb9a4ff79dd96af7fccdc5f8.json"}}, {"family": "Ljung", "given": "Karin", "initials": "K", "orcid": "0000-0003-2901-189X", "researcher": {"href": "https://publications.scilifelab.se/researcher/f91b1e1f90c24559b915ebcd265804a4.json"}}, {"family": "Di Paola", "given": "Luisa", "initials": "L"}, {"family": "Mar\u00e9e", "given": "Athanasius F M", "initials": "AFM"}, {"family": "Costantino", "given": "Paolo", "initials": "P"}, {"family": "Grieneisen", "given": "Ver\u00f4nica A", "initials": "VA"}, {"family": "Sabatini", "given": "Sabrina", "initials": "S"}], "type": "journal article", "published": "2017-09-05", "journal": {"title": "Proc. Natl. Acad. Sci. U.S.A.", "issn": "1091-6490", "volume": "114", "issue": "36", "pages": "E7641-E7649", "issn-l": "0027-8424"}, "abstract": "In multicellular organisms, a stringent control of the transition between cell division and differentiation is crucial for correct tissue and organ development. In the Arabidopsis root, the boundary between dividing and differentiating cells is positioned by the antagonistic interaction of the hormones auxin and cytokinin. Cytokinin affects polar auxin transport, but how this impacts the positional information required to establish this tissue boundary, is still unknown. By combining computational modeling with molecular genetics, we show that boundary formation is dependent on cytokinin's control on auxin polar transport and degradation. The regulation of both processes shapes the auxin profile in a well-defined auxin minimum. This auxin minimum positions the boundary between dividing and differentiating cells, acting as a trigger for this developmental transition, thus controlling meristem size.", "doi": "10.1073/pnas.1705833114", "pmid": "28831001", "labels": {"Swedish Metabolomics Centre": "Service"}, "xrefs": [{"db": "pii", "key": "1705833114"}, {"db": "pmc", "key": "PMC5594665"}], "notes": [], "created": "2018-01-09T12:29:37.442Z", "modified": "2025-10-17T13:03:18.557Z"}]}