{"entity": "researcher", "timestamp": "2026-08-17T02:28:11.804Z", "family": "Novakazi", "given": "Flutur\u00eb", "initials": "F", "orcid": "0000-0001-7151-6811", "affiliations": [], "links": {"self": {"href": "https://publications.scilifelab.se/researcher/5812b915262d44e4972483c8314675c3.json"}, "display": {"href": "https://publications.scilifelab.se/researcher/5812b915262d44e4972483c8314675c3"}}, "publications": [{"entity": "publication", "iuid": "adaf9a93a2bd4c25a95e6c65cbef74c7", "links": {"self": {"href": "https://publications.scilifelab.se/publication/adaf9a93a2bd4c25a95e6c65cbef74c7.json"}, "display": {"href": "https://publications.scilifelab.se/publication/adaf9a93a2bd4c25a95e6c65cbef74c7"}}, "title": "Pyramiding of scald resistance genes in four spring barley MAGIC populations.", "authors": [{"family": "Hautsalo", "given": "Juho", "initials": "J", "orcid": "0000-0003-2501-2297", "researcher": {"href": "https://publications.scilifelab.se/researcher/838159575f394d7f8a4ddf4e00ef716c.json"}}, {"family": "Novakazi", "given": "Flutur\u00eb", "initials": "F", "orcid": "0000-0001-7151-6811", "researcher": {"href": "https://publications.scilifelab.se/researcher/5812b915262d44e4972483c8314675c3.json"}}, {"family": "Jalli", "given": "Marja", "initials": "M"}, {"family": "G\u00f6ransson", "given": "Magnus", "initials": "M", "orcid": "0000-0002-0081-2207", "researcher": {"href": "https://publications.scilifelab.se/researcher/13cca49312994a8fa45dc1fb7db8a42f.json"}}, {"family": "Manninen", "given": "Outi", "initials": "O", "orcid": "0000-0001-9641-6657", "researcher": {"href": "https://publications.scilifelab.se/researcher/ec5965b7edd0413791c990a978f17045.json"}}, {"family": "Isolahti", "given": "Mika", "initials": "M"}, {"family": "Reitan", "given": "Lars", "initials": "L"}, {"family": "Bergersen", "given": "Stein", "initials": "S"}, {"family": "Krusell", "given": "Lene", "initials": "L"}, {"family": "Damsg\u00e5rd Robertsen", "given": "Charlotte", "initials": "C"}, {"family": "Orabi", "given": "Jihad", "initials": "J"}, {"family": "Due Jensen", "given": "Jens", "initials": "J"}, {"family": "Jahoor", "given": "Ahmed", "initials": "A"}, {"family": "Bengtsson", "given": "Ther\u00e9se", "initials": "T", "orcid": "0000-0003-4784-1723", "researcher": {"href": "https://publications.scilifelab.se/researcher/0ec4d4a00bcf4fd59113eb264283b92a.json"}}, {"family": "PPP Barley Consortium", "given": "", "initials": ""}], "type": "journal article", "published": "2021-12-00", "journal": {"title": "Theor. Appl. Genet.", "issn": "1432-2242", "issn-l": "0040-5752", "volume": "134", "issue": "12", "pages": "3829-3843"}, "abstract": "Genome-Wide Association Studies (GWAS) of four Multi-parent Advanced Generation Inter-Cross (MAGIC) populations identified nine regions on chromosomes 1H, 3H, 4H, 5H, 6H and 7H associated with resistance against barley scald disease. Three of these regions are putatively novel resistance Quantitative Trait Loci (QTL). Barley scald is caused by Rhynchosporium commune, one of the most important barley leaf diseases that are prevalent in most barley-growing regions. Up to 40% yield losses can occur in susceptible barley cultivars. Four MAGIC populations were generated in a Nordic Public-Private Pre-breeding of spring barley project (PPP Barley) to introduce resistance to several important diseases. Here, these MAGIC populations consisting of six to eight founders each were tested for scald resistance in field trials in Finland and Iceland. Eight different model covariate combinations were compared for GWAS studies, and the models that deviated the least from the expected p-values were selected. For all QTL, candidate genes were identified that are predicted to be involved in pathogen defence. The MAGIC progenies contained new haplotypes of significant SNP-markers with high resistance levels. The lines with successfully pyramided resistance against scald and mildew and the significant markers are now distributed among Nordic plant breeders and will benefit development of disease-resistant cultivars.", "doi": "10.1007/s00122-021-03930-y", "pmid": "34350474", "labels": {"NGI Uppsala (SNP&SEQ Technology Platform)": "Service", "National Genomics Infrastructure": "Service"}, "xrefs": [{"db": "pii", "key": "10.1007/s00122-021-03930-y"}, {"db": "pmc", "key": "PMC8580920"}], "notes": [], "created": "2021-08-19T13:41:40.899Z", "modified": "2021-12-07T06:55:41.799Z"}, {"entity": "publication", "iuid": "f046cb0689f843a8833a93b6acea2080", "links": {"self": {"href": "https://publications.scilifelab.se/publication/f046cb0689f843a8833a93b6acea2080.json"}, "display": {"href": "https://publications.scilifelab.se/publication/f046cb0689f843a8833a93b6acea2080"}}, "title": "You Had Me at \u201cMAGIC\u201d!: Four Barley MAGIC Populations Reveal Novel Resistance QTL for Powdery Mildew", "authors": [{"family": "Novakazi", "given": "Flutur\u00eb", "initials": "F", "orcid": "0000-0001-7151-6811", "researcher": {"href": "https://publications.scilifelab.se/researcher/5812b915262d44e4972483c8314675c3.json"}}, {"family": "Krusell", "given": "Lene", "initials": "L"}, {"family": "Jensen", "given": "Jens", "initials": "J"}, {"family": "Orabi", "given": "Jihad", "initials": "J", "orcid": "0000-0001-9641-6657", "researcher": {"href": "https://publications.scilifelab.se/researcher/ec5965b7edd0413791c990a978f17045.json"}}, {"family": "Jahoor", "given": "Ahmed", "initials": "A"}, {"family": "Bengtsson", "given": "Ther\u00e9se", "initials": "T", "orcid": "0000-0003-4784-1723", "researcher": {"href": "https://publications.scilifelab.se/researcher/0ec4d4a00bcf4fd59113eb264283b92a.json"}}, {"family": null, "given": "", "initials": ""}], "type": "journal-article", "published": "2020-12-18", "journal": {"title": "Genes", "issn": "2073-4425", "issn-l": "2073-4425", "volume": "11", "issue": "12", "pages": "1512"}, "abstract": "Blumeria graminis f. sp. hordei (Bgh), the causal agent of barley powdery mildew (PM), is one of the most important barley leaf diseases and is prevalent in most barley growing regions. Infection decreases grain quality and yields on average by 30%. Multi-parent advanced generation inter-cross (MAGIC) populations combine the advantages of bi-parental and association panels and offer the opportunity to incorporate exotic alleles into adapted material. Here, four barley MAGIC populations consisting of six to eight founders were tested for PM resistance in field trials in Denmark. Principle component and STRUCTURE analysis showed the populations were unstructured and genome-wide linkage disequilibrium (LD) decay varied between 14 and 38 Mbp. Genome-wide association studies (GWAS) identified 11 regions associated with PM resistance located on chromosomes 1H, 2H, 3H, 4H, 5H and 7H, of which three regions are putatively novel resistance quantitative trait locus/loci (QTL). For all regions high-confidence candidate genes were identified that are predicted to be involved in pathogen defense. Haplotype analysis of the significant SNPs revealed new allele combinations not present in the founders and associated with high resistance levels.", "doi": "10.3390/genes11121512", "pmid": "33352820", "labels": {"NGI Uppsala (SNP&SEQ Technology Platform)": "Service", "National Genomics Infrastructure": "Service"}, "xrefs": [{"db": "pmc", "key": "PMC7766815"}, {"db": "pii", "key": "genes11121512"}], "notes": [], "created": "2020-12-28T17:52:37.985Z", "modified": "2023-06-19T11:38:46.230Z"}]}