{"entity": "researcher", "timestamp": "2026-07-22T16:33:18.454Z", "family": "Walker", "given": "Catriona H", "initials": "CH", "orcid": "0000-0001-7854-4348", "affiliations": ["School of Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK."], "links": {"self": {"href": "https://publications.scilifelab.se/researcher/37ada8225d8e4931b1d093af5a71306e.json"}, "display": {"href": "https://publications.scilifelab.se/researcher/37ada8225d8e4931b1d093af5a71306e"}}, "publications": [{"entity": "publication", "iuid": "a77d37158afd4ede8f43dcf11d98841e", "links": {"self": {"href": "https://publications.scilifelab.se/publication/a77d37158afd4ede8f43dcf11d98841e.json"}, "display": {"href": "https://publications.scilifelab.se/publication/a77d37158afd4ede8f43dcf11d98841e"}}, "title": "Cytokinin signaling regulates two-stage inflorescence arrest in Arabidopsis.", "authors": [{"family": "Walker", "given": "Catriona H", "initials": "CH", "orcid": "0000-0001-7854-4348", "researcher": {"href": "https://publications.scilifelab.se/researcher/37ada8225d8e4931b1d093af5a71306e.json"}}, {"family": "Ware", "given": "Alexander", "initials": "A", "orcid": "0000-0002-0723-178X", "researcher": {"href": "https://publications.scilifelab.se/researcher/f81ec7512ffb4c70bc61f7b433dd18b5.json"}}, {"family": "\u0160imura", "given": "Jan", "initials": "J"}, {"family": "Ljung", "given": "Karin", "initials": "K", "orcid": "0000-0003-2901-189X", "researcher": {"href": "https://publications.scilifelab.se/researcher/f91b1e1f90c24559b915ebcd265804a4.json"}}, {"family": "Wilson", "given": "Zoe", "initials": "Z", "orcid": "0000-0003-0948-8770", "researcher": {"href": "https://publications.scilifelab.se/researcher/76cb7bfa2b1c4961ad52a2080f7c9822.json"}}, {"family": "Bennett", "given": "Tom", "initials": "T", "orcid": "0000-0003-1612-4019", "researcher": {"href": "https://publications.scilifelab.se/researcher/f39f318b0f094229aa34d1c137575d6b.json"}}], "type": "journal article", "published": "2023-01-02", "journal": {"title": "Plant Physiol.", "issn": "1532-2548", "volume": "191", "issue": "1", "pages": "479-495", "issn-l": "0032-0889"}, "abstract": "To maximize reproductive success, flowering plants must correctly time entry and exit from the reproductive phase. While much is known about mechanisms that regulate initiation of flowering, end-of-flowering remains largely uncharacterized. End-of-flowering in Arabidopsis (Arabidopsis thaliana) consists of quasi-synchronous arrest of inflorescences, but it is unclear how arrest is correctly timed with respect to environmental stimuli and reproductive success. Here, we showed that Arabidopsis inflorescence arrest is a complex developmental phenomenon, which includes the arrest of the inflorescence meristem (IM), coupled with a separable \"floral arrest\" of all unopened floral primordia; these events occur well before visible inflorescence arrest. We showed that global inflorescence removal delays both IM and floral arrest, but that local fruit removal only delays floral arrest, emphasizing their separability. We tested whether cytokinin regulates inflorescence arrest, and found that cytokinin signaling dynamics mirror IM activity, while cytokinin treatment can delay both IM and floral arrest. We further showed that gain-of-function cytokinin receptor mutants can delay IM and floral arrest; conversely, loss-of-function mutants prevented the extension of flowering in response to inflorescence removal. Collectively, our data suggest that the dilution of cytokinin among an increasing number of sink organs leads to end-of-flowering in Arabidopsis by triggering IM and floral arrest.", "doi": "10.1093/plphys/kiac514", "pmid": "36331332", "labels": {"Swedish Metabolomics Centre": "Service"}, "xrefs": [{"db": "pmc", "key": "PMC9806609"}, {"db": "pii", "key": "6798646"}], "notes": [], "created": "2023-08-30T07:09:54.771Z", "modified": "2025-10-17T13:03:14.503Z"}, {"entity": "publication", "iuid": "c2cb0bab4db649efac151742b39cf0bb", "links": {"self": {"href": "https://publications.scilifelab.se/publication/c2cb0bab4db649efac151742b39cf0bb.json"}, "display": {"href": "https://publications.scilifelab.se/publication/c2cb0bab4db649efac151742b39cf0bb"}}, "title": "Auxin export from proximal fruits drives arrest in temporally competent inflorescences", "authors": [{"family": "Ware", "given": "Alexander", "initials": "A"}, {"family": "Walker", "given": "Catriona H", "initials": "CH", "orcid": "0000-0001-7854-4348", "researcher": {"href": "https://publications.scilifelab.se/researcher/37ada8225d8e4931b1d093af5a71306e.json"}}, {"family": "\u0160imura", "given": "Jan", "initials": "J"}, {"family": "Gonz\u00e1lez-Su\u00e1rez", "given": "Pablo", "initials": "P", "orcid": "0000-0002-2122-5984", "researcher": {"href": "https://publications.scilifelab.se/researcher/770ac95b3e6c44e28967de3fb8fbe149.json"}}, {"family": "Ljung", "given": "Karin", "initials": "K", "orcid": "0000-0003-2901-189X", "researcher": {"href": "https://publications.scilifelab.se/researcher/f91b1e1f90c24559b915ebcd265804a4.json"}}, {"family": "Bishopp", "given": "Anthony", "initials": "A"}, {"family": "Wilson", "given": "Zoe A", "initials": "ZA", "orcid": "0000-0003-0948-8770", "researcher": {"href": "https://publications.scilifelab.se/researcher/76cb7bfa2b1c4961ad52a2080f7c9822.json"}}, {"family": "Bennett", "given": "Tom", "initials": "T", "orcid": "0000-0003-1612-4019", "researcher": {"href": "https://publications.scilifelab.se/researcher/f39f318b0f094229aa34d1c137575d6b.json"}}], "type": "journal-article", "published": "2020-05-25", "journal": {"title": "NPLANTS", "issn": "2055-0278", "issn-l": "2055-0278", "volume": "6", "issue": "6", "pages": "699-707"}, "abstract": "A well-defined set of regulatory pathways control entry into the reproductive phase in flowering plants, but little is known about the mechanistic control of the end-of-flowering despite this being a critical process for optimization of fruit and seed production. Complete fruit removal, or lack of fertile fruit-set, prevents timely inflorescence arrest in Arabidopsis, leading to a previous proposal that a cumulative fruit/seed-derived signal causes simultaneous 'global proliferative arrest'. Recent studies have suggested that inflorescence arrest involves gene expression changes in the inflorescence meristem that are, at least in part, controlled by the FRUITFULL-APETALA2 pathway; however, there is limited understanding of how this process is coordinated at the whole-plant level. Here, we provide a framework for the communication previously inferred in the global proliferative arrest model. We show that the end-of-flowering in Arabidopsis is not 'global' and does not occur synchronously between branches, but rather that the arrest of each inflorescence is a local process, driven by auxin export from fruit proximal to the inflorescence apex. Furthermore, we show that inflorescences are competent for arrest only once they reach a certain developmental age. Understanding the regulation of inflorescence arrest will be of major importance to extending and maximizing crop yields.", "doi": "10.1038/s41477-020-0661-z", "pmid": "32451444", "labels": {"Swedish Metabolomics Centre": "Service"}, "xrefs": [{"db": "pii", "key": "10.1038/s41477-020-0661-z"}], "notes": [], "created": "2020-01-21T10:14:13.466Z", "modified": "2025-10-17T13:03:16.780Z"}]}