{"entity": "researcher", "timestamp": "2026-06-15T16:57:20.713Z", "family": "Dingemanse", "given": "Niels J", "initials": "NJ", "orcid": "0000-0003-3320-0861", "affiliations": ["Ludwig Maximilians University of Munich (LMU), 82152 Munich, Planegg-Martinsried, Germany."], "links": {"self": {"href": "https://publications.scilifelab.se/researcher/364e2f2173244470bc7f9c1feff13bc9.json"}, "display": {"href": "https://publications.scilifelab.se/researcher/364e2f2173244470bc7f9c1feff13bc9"}}, "publications": [{"entity": "publication", "iuid": "0e37ae638f8a41589a54a60d69ead29f", "links": {"self": {"href": "https://publications.scilifelab.se/publication/0e37ae638f8a41589a54a60d69ead29f.json"}, "display": {"href": "https://publications.scilifelab.se/publication/0e37ae638f8a41589a54a60d69ead29f"}}, "title": "Continent-wide genomic signatures of adaptation to urbanisation in a songbird across Europe.", "authors": [{"family": "Salm\u00f3n", "given": "Pablo", "initials": "P", "orcid": "0000-0001-9718-6611", "researcher": {"href": "https://publications.scilifelab.se/researcher/b60bfa8b60174680a1546f283c2ccbc1.json"}}, {"family": "Jacobs", "given": "Arne", "initials": "A", "orcid": "0000-0001-7635-5447", "researcher": {"href": "https://publications.scilifelab.se/researcher/7c375694c76e48279bdc6e7dcc2808a6.json"}}, {"family": "Ahr\u00e9n", "given": "Dag", "initials": "D"}, {"family": "Biard", "given": "Clotilde", "initials": "C", "orcid": "0000-0001-7474-5345", "researcher": {"href": "https://publications.scilifelab.se/researcher/7f2845cc669e41f38f4abc7be2d749c2.json"}}, {"family": "Dingemanse", "given": "Niels J", "initials": "NJ", "orcid": "0000-0003-3320-0861", "researcher": {"href": "https://publications.scilifelab.se/researcher/364e2f2173244470bc7f9c1feff13bc9.json"}}, {"family": "Dominoni", "given": "Davide M", "initials": "DM", "orcid": "0000-0003-2063-9955", "researcher": {"href": "https://publications.scilifelab.se/researcher/f5c5e5b23a174cecb550e7a68cd0b0d7.json"}}, {"family": "Helm", "given": "Barbara", "initials": "B", "orcid": "0000-0002-6648-1463", "researcher": {"href": "https://publications.scilifelab.se/researcher/54eeba33656a4e44a2a8281b9a1d9c6d.json"}}, {"family": "Lundberg", "given": "Max", "initials": "M"}, {"family": "Senar", "given": "Juan Carlos", "initials": "JC", "orcid": "0000-0001-9955-3892", "researcher": {"href": "https://publications.scilifelab.se/researcher/9acb6c1702bf4ce88d24eb8a35b39ae3.json"}}, {"family": "Sprau", "given": "Philipp", "initials": "P"}, {"family": "Visser", "given": "Marcel E", "initials": "ME", "orcid": "0000-0002-1456-1939", "researcher": {"href": "https://publications.scilifelab.se/researcher/87e0c4d6e845447ab627a26c7d12d989.json"}}, {"family": "Isaksson", "given": "Caroline", "initials": "C", "orcid": "0000-0002-6889-1386", "researcher": {"href": "https://publications.scilifelab.se/researcher/30ddbca044f64cb1b1feef58baf539ba.json"}}], "type": "journal article", "published": "2021-05-20", "journal": {"title": "Nat Commun", "issn": "2041-1723", "volume": "12", "issue": "1", "pages": "2983", "issn-l": "2041-1723"}, "abstract": "Urbanisation is increasing worldwide, and there is now ample evidence of phenotypic changes in wild organisms in response to this novel environment. Yet, the genetic changes and genomic architecture underlying these adaptations are poorly understood. Here, we genotype 192 great tits (Parus major) from nine European cities, each paired with an adjacent rural site, to address this major knowledge gap in our understanding of wildlife urban adaptation. We find that a combination of polygenic allele frequency shifts and recurrent selective sweeps are associated with the adaptation of great tits to urban environments. While haplotypes under selection are rarely shared across urban populations, selective sweeps occur within the same genes, mostly linked to neural function and development. Collectively, we show that urban adaptation in a widespread songbird occurs through unique and shared selective sweeps in a core-set of behaviour-linked genes.", "doi": "10.1038/s41467-021-23027-w", "pmid": "34016968", "labels": {"Bioinformatics Support, Infrastructure and Training": "Collaborative", "Bioinformatics Support and Infrastructure": "Collaborative", "Bioinformatics (NBIS)": "Collaborative"}, "xrefs": [{"db": "pii", "key": "10.1038/s41467-021-23027-w"}, {"db": "pmc", "key": "PMC8137928"}], "notes": [], "created": "2021-12-10T09:50:47.664Z", "modified": "2021-12-10T09:50:47.897Z"}, {"entity": "publication", "iuid": "fdff2262424e46cc949c4ce71f7b8f59", "links": {"self": {"href": "https://publications.scilifelab.se/publication/fdff2262424e46cc949c4ce71f7b8f59.json"}, "display": {"href": "https://publications.scilifelab.se/publication/fdff2262424e46cc949c4ce71f7b8f59"}}, "title": "Intra-Individual Behavioural Variability: A Trait under Genetic Control.", "authors": [{"family": "Henriksen", "given": "Rie", "initials": "R"}, {"family": "H\u00f6glund", "given": "Andrey", "initials": "A", "orcid": "0000-0002-1130-374X", "researcher": {"href": "https://publications.scilifelab.se/researcher/70a484451caf40f2a1a196b36bb9c423.json"}}, {"family": "Fogelholm", "given": "Jesper", "initials": "J", "orcid": "0000-0002-0868-8722", "researcher": {"href": "https://publications.scilifelab.se/researcher/5dc8c561c04f437991504aca4c86593d.json"}}, {"family": "Abbey-Lee", "given": "Robin", "initials": "R"}, {"family": "Johnsson", "given": "Martin", "initials": "M"}, {"family": "Dingemanse", "given": "Niels J", "initials": "NJ", "orcid": "0000-0003-3320-0861", "researcher": {"href": "https://publications.scilifelab.se/researcher/364e2f2173244470bc7f9c1feff13bc9.json"}}, {"family": "Wright", "given": "Dominic", "initials": "D", "orcid": "0000-0003-2329-2635", "researcher": {"href": "https://publications.scilifelab.se/researcher/6447b896ea3b453ab10136b5f44ae241.json"}}], "type": "journal article", "published": "2020-10-29", "journal": {"title": "Int J Mol Sci", "issn": "1422-0067", "issn-l": null, "volume": "21", "issue": "21", "pages": "8069"}, "abstract": "When individuals are measured more than once in the same context they do not behave in exactly the same way each time. The degree of predictability differs between individuals, with some individuals showing low levels of variation around their behavioural mean while others show high levels of variation. This intra-individual variability in behaviour has received much less attention than between-individual variability in behaviour, and very little is known about the underlying mechanisms that affect this potentially large but understudied component of behavioural variation. In this study, we combine standardized behavioural tests in a chicken intercross to estimate intra-individual behavioural variability with a large-scale genomics analysis to identify genes affecting intra-individual behavioural variability in an avian population. We used a variety of different anxiety-related behavioural phenotypes for this purpose. Our study shows that intra-individual variability in behaviour has a direct genetic basis that is largely unique compared to the genetic architecture for the standard behavioural measures they are based on (at least in the detected quantitative trait locus). We identify six suggestive candidate genes that may underpin differences in intra-individual behavioural variability, with several of these candidates having previously been linked to behaviour and mental health. These findings demonstrate that intra-individual variability in behaviour appears to be a heritable trait in and of itself on which evolution can act.", "doi": "10.3390/ijms21218069", "pmid": "33138119", "labels": {"NGI Uppsala (SNP&SEQ Technology Platform)": "Service", "National Genomics Infrastructure": "Service", "Bioinformatics Support for Computational Resources": "Service"}, "xrefs": [{"db": "pii", "key": "ijms21218069"}, {"db": "pmc", "key": "PMC7663371"}], "notes": [], "created": "2021-01-12T13:47:04.128Z", "modified": "2024-01-16T13:48:41.496Z"}]}