{"entity": "publication", "iuid": "ddf03b5f1f1c47209a97f015b429d9c4", "timestamp": "2026-08-10T14:06:49.521Z", "links": {"self": {"href": "https://publications.scilifelab.se/publication/ddf03b5f1f1c47209a97f015b429d9c4.json"}, "display": {"href": "https://publications.scilifelab.se/publication/ddf03b5f1f1c47209a97f015b429d9c4"}}, "title": "On the origin of the widespread self-compatible allotetraploid Capsella bursa-pastoris (Brassicaceae).", "authors": [{"family": "Bachmann", "given": "J\u00f6rg A", "initials": "JA", "orcid": "0000-0002-7212-813X", "researcher": {"href": "https://publications.scilifelab.se/researcher/7dadd1300e85443d8ee98a2d58d08a4b.json"}}, {"family": "Tedder", "given": "Andrew", "initials": "A", "orcid": "0000-0002-7378-4673", "researcher": {"href": "https://publications.scilifelab.se/researcher/8a29b3c1160f46bf8b21e331268eb4b1.json"}}, {"family": "Fracassetti", "given": "Marco", "initials": "M", "orcid": "0000-0002-2962-2669", "researcher": {"href": "https://publications.scilifelab.se/researcher/695213cdd1a645cbbf10d44122237b18.json"}}, {"family": "Steige", "given": "Kim A", "initials": "KA"}, {"family": "Lafon-Placette", "given": "Cl\u00e9ment", "initials": "C"}, {"family": "K\u00f6hler", "given": "Claudia", "initials": "C", "orcid": "0000-0002-2619-4857", "researcher": {"href": "https://publications.scilifelab.se/researcher/accd3f9307614c8ab67154dd5e50cdac.json"}}, {"family": "Slotte", "given": "Tanja", "initials": "T"}], "type": "journal article", "published": "2021-07-00", "journal": {"title": "Heredity (Edinb)", "issn": "1365-2540", "issn-l": "0018-067X", "volume": "127", "issue": "1", "pages": "124-134"}, "abstract": "Polyploidy, or whole-genome duplication, is a common speciation mechanism in plants. An important barrier to polyploid establishment is a lack of compatible mates. Because self-compatibility alleviates this problem, it has long been hypothesized that there should be an association between polyploidy and self-compatibility (SC), but empirical support for this prediction is mixed. Here, we investigate whether the molecular makeup of the Brassicaceae self-incompatibility (SI) system, and specifically dominance relationships among S-haplotypes mediated by small RNAs, could facilitate loss of SI in allopolyploid crucifers. We focus on the allotetraploid species Capsella bursa-pastoris, which formed ~300 kya by hybridization and whole-genome duplication involving progenitors from the lineages of Capsella orientalis and Capsella grandiflora. We conduct targeted long-read sequencing to assemble and analyze eight full-length S-locus haplotypes, representing both homeologous subgenomes of C. bursa-pastoris. We further analyze small RNA (sRNA) sequencing data from flower buds to identify candidate dominance modifiers. We find that C. orientalis-derived S-haplotypes of C. bursa-pastoris harbor truncated versions of the male SI specificity gene SCR and express a conserved sRNA-based candidate dominance modifier with a target in the C. grandiflora-derived S-haplotype. These results suggest that pollen-level dominance may have facilitated loss of SI in C. bursa-pastoris. Finally, we demonstrate that spontaneous somatic tetraploidization after a wide cross between C. orientalis and C. grandiflora can result in production of self-compatible tetraploid offspring. We discuss the implications of this finding on the mode of formation of this widespread weed.", "doi": "10.1038/s41437-021-00434-9", "pmid": "33875831", "labels": {"NGI Uppsala (SNP&SEQ Technology Platform)": "Service", "National Genomics Infrastructure": "Service", "NGI Stockholm (Genomics Production)": "Service", "NGI Stockholm (Genomics Applications)": "Service", "NGI Uppsala (Uppsala Genome Center)": "Service", "Bioinformatics Support for Computational Resources": "Service"}, "xrefs": [{"db": "pii", "key": "10.1038/s41437-021-00434-9"}, {"db": "pmc", "key": "PMC8249383"}], "notes": [], "created": "2021-09-02T09:52:09.038Z", "modified": "2024-01-16T13:48:39.247Z"}