{"entity": "publication", "iuid": "5ef10a01a35845139e73fd3393b8b2a7", "timestamp": "2026-08-18T22:47:42.571Z", "links": {"self": {"href": "https://publications.scilifelab.se/publication/5ef10a01a35845139e73fd3393b8b2a7.json"}, "display": {"href": "https://publications.scilifelab.se/publication/5ef10a01a35845139e73fd3393b8b2a7"}}, "title": "Data on haplotype-supported immunoglobulin germline gene inference.", "authors": [{"family": "Kirik", "given": "Ufuk", "initials": "U"}, {"family": "Greiff", "given": "Lennart", "initials": "L"}, {"family": "Levander", "given": "Fredrik", "initials": "F"}, {"family": "Ohlin", "given": "Mats", "initials": "M"}], "type": "journal article", "published": "2017-08-00", "journal": {"volume": "13", "issn": "2352-3409", "issue": null, "pages": "620-640", "title": "Data Brief", "issn-l": "2352-3409"}, "abstract": "Data that defines IGHV (immunoglobulin heavy chain variable) germline gene inference using sequences of IgM-encoding transcriptomes obtained by Illumina MiSeq sequencing technology are described. Such inference is used to establish personalized germline gene sets for in-depth antibody repertoire studies and to detect new antibody germline genes from widely available immunoglobulin-encoding transcriptome data sets. Specifically, the data has been used to validate (Parallel antibody germline gene and haplotype analyses support the validity of immunoglobulin germline gene inference and discovery (DOI: 10.1016/j.molimm.2017.03.012) (Kirik et al., 2017) [1]) the inference process. This was accomplished based on analysis of the inferred germline genes' association to the donors' different haplotypes as defined by their different, expressed IGHJ alleles and/or IGHD genes/alleles. The data is important for development of validated germline gene databases containing entries inferred from immunoglobulin-encoding transcriptome sequencing data sets, and for generation of valid, personalized antibody germline gene repertoires.", "doi": "10.1016/j.dib.2017.06.031", "pmid": "28725665", "labels": {"National Genomics Infrastructure": "Service", "NGI Stockholm (Genomics Applications)": "Service", "NGI Stockholm (Genomics Production)": "Service", "Bioinformatics Support for Computational Resources": "Service"}, "xrefs": [{"db": "pii", "key": "S2352-3409(17)30275-5"}, {"db": "pmc", "key": "PMC5502703"}], "notes": [], "created": "2017-11-03T16:22:11.988Z", "modified": "2024-01-16T13:48:47.688Z"}