{"entity": "publication", "iuid": "4fd1515f4ad64f6792ce578cadcba6d2", "timestamp": "2026-09-12T19:30:55.185Z", "links": {"self": {"href": "https://publications.scilifelab.se/publication/4fd1515f4ad64f6792ce578cadcba6d2.json"}, "display": {"href": "https://publications.scilifelab.se/publication/4fd1515f4ad64f6792ce578cadcba6d2"}}, "title": "Whole-body fat oxidation increases more by prior exercise than overnight fasting in elite endurance athletes.", "authors": [{"family": "Andersson Hall", "given": "Ulrika", "initials": "U"}, {"family": "Edin", "given": "Fredrik", "initials": "F"}, {"family": "Pedersen", "given": "Anders", "initials": "A"}, {"family": "Madsen", "given": "Klavs", "initials": "K"}], "type": "journal article", "published": "2016-04-00", "journal": {"volume": "41", "issn": "1715-5320", "issue": "4", "pages": "430-437", "title": "Appl Physiol Nutr Metab", "issn-l": "1715-5312"}, "abstract": "The purpose of this study was to compare whole-body fat oxidation kinetics after prior exercise with overnight fasting in elite endurance athletes. Thirteen highly trained athletes (9 men and 4 women; maximal oxygen uptake: 66 \u00b1 1 mL\u00b7min(-1)\u00b7kg(-1)) performed 3 identical submaximal incremental tests on a cycle ergometer using a cross-over design. A control test (CON) was performed 3 h after a standardized breakfast, a fasting test (FAST) 12 h after a standardized evening meal, and a postexercise test (EXER) after standardized breakfast, endurance exercise, and 2 h fasting recovery. The test consisted of 3 min each at 30%, 40%, 50%, 60%, 70%, and 80% of maximal oxygen uptake and fat oxidation rates were measured through indirect calorimetry. During CON, maximal fat oxidation rate was 0.51 \u00b1 0.04 g\u00b7min(-1) compared with 0.69 \u00b1 0.04 g\u00b7min(-1) in FAST (P < 0.01), and 0.89 \u00b1 0.05 g\u00b7min(-1) in EXER (P < 0.01). Across all intensities, EXER was significantly higher than FAST and FAST was higher than CON (P < 0.01). Blood insulin levels were lower and free fatty acid and cortisol levels were higher at the start of EXER compared with CON and FAST (P < 0.05). Plasma nuclear magnetic resonance-metabolomics showed similar changes in both EXER and FAST, including increased levels of fatty acids and succinate. In conclusion, prior exercise significantly increases whole-body fat oxidation during submaximal exercise compared with overnight fasting. Already high rates of maximal fat oxidation in elite endurance athletes were increased by approximately 75% after prior exercise and fasting recovery.", "doi": "10.1139/apnm-2015-0452", "pmid": "26988766", "labels": {"Bioinformatics Support, Infrastructure and Training": "Service", "Bioinformatics Support and Infrastructure": "Service", "Bioinformatics (NBIS)": "Service", "Swedish NMR Centre": "Collaborative"}, "xrefs": [], "notes": [], "created": "2017-05-03T13:00:45.921Z", "modified": "2025-10-17T13:04:00.566Z"}