{"entity": "publication", "iuid": "2ec4096268f347c79eedea7bb77234a9", "timestamp": "2026-03-05T08:50:42.091Z", "links": {"self": {"href": "https://publications.scilifelab.se/publication/2ec4096268f347c79eedea7bb77234a9.json"}, "display": {"href": "https://publications.scilifelab.se/publication/2ec4096268f347c79eedea7bb77234a9"}}, "title": "Determinants of genetic variation across eco-evolutionary scales in pinnipeds.", "authors": [{"family": "Peart", "given": "Claire R", "initials": "CR", "orcid": "0000-0002-0433-0299", "researcher": {"href": "https://publications.scilifelab.se/researcher/39ca9ce827fb435195a0d5bee245ba6a.json"}}, {"family": "Tusso", "given": "Sergio", "initials": "S", "orcid": "0000-0002-0612-9230", "researcher": {"href": "https://publications.scilifelab.se/researcher/027fc05d9bd843afaa82aeecce0747e8.json"}}, {"family": "Pophaly", "given": "Saurabh D", "initials": "SD"}, {"family": "Botero-Castro", "given": "Fidel", "initials": "F", "orcid": "0000-0002-5062-8272", "researcher": {"href": "https://publications.scilifelab.se/researcher/7ef9abb38c5d4c259d64e6f59ee7440c.json"}}, {"family": "Wu", "given": "Chi-Chih", "initials": "CC"}, {"family": "Aurioles-Gamboa", "given": "David", "initials": "D"}, {"family": "Baird", "given": "Amy B", "initials": "AB"}, {"family": "Bickham", "given": "John W", "initials": "JW", "orcid": "0000-0001-9624-7806", "researcher": {"href": "https://publications.scilifelab.se/researcher/5b8ef9c3991c4da38ad3010bb30977be.json"}}, {"family": "Forcada", "given": "Jaume", "initials": "J", "orcid": "0000-0002-2115-0150", "researcher": {"href": "https://publications.scilifelab.se/researcher/c9fddd47f5b64f779913b9fd631edb2e.json"}}, {"family": "Galimberti", "given": "Filippo", "initials": "F", "orcid": "0000-0001-5537-6409", "researcher": {"href": "https://publications.scilifelab.se/researcher/9d82a8f8835145619fbac351091bfbec.json"}}, {"family": "Gemmell", "given": "Neil J", "initials": "NJ", "orcid": "0000-0003-0671-3637", "researcher": {"href": "https://publications.scilifelab.se/researcher/9ca2b0a676d84b878b3f9faa8748e148.json"}}, {"family": "Hoffman", "given": "Joseph I", "initials": "JI", "orcid": "0000-0001-5895-8949", "researcher": {"href": "https://publications.scilifelab.se/researcher/5455275134754093b050bee85b8f88c5.json"}}, {"family": "Kovacs", "given": "Kit M", "initials": "KM"}, {"family": "Kunnasranta", "given": "Mervi", "initials": "M"}, {"family": "Lydersen", "given": "Christian", "initials": "C"}, {"family": "Nyman", "given": "Tommi", "initials": "T"}, {"family": "de Oliveira", "given": "Larissa Rosa", "initials": "LR"}, {"family": "Orr", "given": "Anthony J", "initials": "AJ"}, {"family": "Sanvito", "given": "Simona", "initials": "S", "orcid": "0000-0003-1427-6414", "researcher": {"href": "https://publications.scilifelab.se/researcher/1f65216b298b4575adb46bfeea38d8d3.json"}}, {"family": "Valtonen", "given": "Mia", "initials": "M", "orcid": "0000-0003-2034-2019", "researcher": {"href": "https://publications.scilifelab.se/researcher/601fe0084ca1460486e607e509f46c3a.json"}}, {"family": "Shafer", "given": "Aaron B A", "initials": "ABA", "orcid": "0000-0001-7652-225X", "researcher": {"href": "https://publications.scilifelab.se/researcher/65325cc227b74704ab85e14385a1673e.json"}}, {"family": "Wolf", "given": "Jochen B W", "initials": "JBW", "orcid": "0000-0002-2958-5183", "researcher": {"href": "https://publications.scilifelab.se/researcher/6c4445d760a64905a9ea6d8664f6a32d.json"}}], "type": "journal article", "published": "2020-08-00", "journal": {"title": "Nat Ecol Evol", "issn": "2397-334X", "volume": "4", "issue": "8", "pages": "1095-1104", "issn-l": "2397-334X"}, "abstract": "The effective size of a population (Ne), which determines its level of neutral variability, is a key evolutionary parameter. Ne can substantially depart from census sizes of present-day breeding populations (NC) as a result of past demographic changes, variation in life-history traits and selection at linked sites. Using genome-wide data we estimated the long-term coalescent Ne for 17 pinniped species represented by 36 population samples (total n = 458 individuals). Ne estimates ranged from 8,936 to 91,178, were highly consistent within (sub)species and showed a strong positive correlation with NC ([Formula: see text] = 0.59; P = 0.0002). Ne/NC ratios were low (mean, 0.31; median, 0.13) and co-varied strongly with demographic history and, to a lesser degree, with species' ecological and life-history variables such as breeding habitat. Residual variation in Ne/NC, after controlling for past demographic fluctuations, contained information about recent population size changes during the Anthropocene. Specifically, species of conservation concern typically had positive residuals indicative of a smaller contemporary NC than would be expected from their long-term Ne. This study highlights the value of comparative population genomic analyses for gauging the evolutionary processes governing genetic variation in natural populations, and provides a framework for identifying populations deserving closer conservation attention.", "doi": "10.1038/s41559-020-1215-5", "pmid": "32514167", "labels": {"National Genomics Infrastructure": "Service", "NGI Uppsala (SNP&SEQ Technology Platform)": "Service", "Bioinformatics Support for Computational Resources": "Service"}, "xrefs": [{"db": "pii", "key": "10.1038/s41559-020-1215-5"}], "notes": [], "created": "2020-12-08T23:33:13.775Z", "modified": "2024-01-16T13:48:42.060Z"}