{"entity": "publication", "iuid": "1d9eb844850341998a3431de40af9557", "timestamp": "2026-10-11T06:18:53.920Z", "links": {"self": {"href": "https://publications.scilifelab.se/publication/1d9eb844850341998a3431de40af9557.json"}, "display": {"href": "https://publications.scilifelab.se/publication/1d9eb844850341998a3431de40af9557"}}, "title": "Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5", "authors": [{"family": "Rossi Sebastiano", "given": "Matteo", "initials": "M"}, {"family": "Doak", "given": "Bradley C", "initials": "BC"}, {"family": "Backlund", "given": "Maria", "initials": "M"}, {"family": "Poongavanam", "given": "Vasanthanathan", "initials": "V"}, {"family": "Over", "given": "Bj\u00f6rn", "initials": "B"}, {"family": "Ermondi", "given": "Giuseppe", "initials": "G"}, {"family": "Caron", "given": "Giulia", "initials": "G"}, {"family": "Matsson", "given": "P\u00e4r", "initials": "P"}, {"family": "Kihlberg", "given": "Jan", "initials": "J"}], "type": "journal-article", "published": "2018-05-10", "journal": {"volume": "61", "issn": "1520-4804", "issue": "9", "pages": "4189-4202", "title": "J. Med. Chem.", "issn-l": "0022-2623"}, "abstract": null, "doi": "10.1021/acs.jmedchem.8b00347", "pmid": "29608068", "labels": {"Chemical Biology Consortium Sweden": "Service", "Drug Discovery and Development": "Service"}, "xrefs": [], "notes": [], "created": "2018-10-22T13:12:40.051Z", "modified": "2025-10-17T13:05:08.445Z"}