Targeted and Structural Proteomics

SciLifeLab Infrastructure Unit Since 2021.

Started: 2021

Ended: Current

55 publications

Year 2020

A dual-action peptide-containing hydrogel targets wound infection and inflammation
Puthia M, Butrym M, Petrlova J, ..., Kjellström S, Schmidtchen A
Sci. Transl. Med. 12 (524) eaax6601 [2020-01-01; online 2020-01-01]
Targeted and Structural Proteomics [Collaborative]

Year 2019

Wnt5a is a TLR2/4-ligand that induces tolerance in human myeloid cells
Mehmeti M, Bergenfelz C, Källberg E, ..., André I, Leandersson K
Commun Biol 2 (1) - [2019-12-00; online 2019-05-09]
Targeted and Structural Proteomics [Service]
Identification of two abundant Aerococcus urinae cell wall-anchored proteins.
Senneby E, Sunnerhagen T, Hallström B, ..., Karlsson C, Rasmussen M
pii: S1438-4221(18)30350-3
Int. J. Med. Microbiol. 309 (7) 151325 [2019-11-00; online 2019-06-24]
Targeted and Structural Proteomics [Collaborative]
Novel functional proteins coded by the human genome discovered in metastases of melanoma patients.
Sanchez A, Kuras M, Murillo JR, ..., Betancourt LH, Marko-Varga G
pii: 10.1007/s10565-019-09494-4
Cell Biol. Toxicol. - (-) - [2019-10-10; online 2019-10-10]
Targeted and Structural Proteomics [Service]
Global extracellular vesicle proteomic signature defines U87-MG glioma cell hypoxic status with potential implications for non-invasive diagnostics.
Indira Chandran V, Welinder C, Gonçalves de Oliveira K, ..., Marko-Varga G, Belting M
pii: 10.1007/s11060-019-03262-4 pmc: PMC6764937
J. Neurooncol. 144 (3) 477-488 [2019-09-00; online 2019-08-14]
Targeted and Structural Proteomics [Service]
Matrisome Properties of Scaffolds Direct Fibroblasts in Idiopathic Pulmonary Fibrosis.
Elowsson Rendin L, Löfdahl A, Åhrman E, ..., Malmström J, Westergren-Thorsson G
pii: ijms20164013 pmc: PMC6719040
Int J Mol Sci 20 (16) - [2019-08-17; online 2019-08-17]
Targeted and Structural Proteomics [Collaborative]
Clinical protein science in translational medicine targeting malignant melanoma.
Gil J, Betancourt LH, Pla I, ..., Malm J, Marko-Varga G
pii: 10.1007/s10565-019-09468-6 pmc: PMC6757020
Cell Biol. Toxicol. 35 (4) 293-332 [2019-08-00; online 2019-03-21]
Targeted and Structural Proteomics [Service]
Streptococcus pyogenes evades adaptive immunity through specific IgG glycan hydrolysis.
Naegeli A, Bratanis E, Karlsson C, ..., Malmström J, Collin M
pii: jem.20190293 pmc: PMC6605743
J. Exp. Med. 216 (7) 1615-1629 [2019-07-01; online 2019-05-15]
Targeted and Structural Proteomics [Collaborative]
Structural Basis for YjbH Adaptor-Mediated Recognition of Transcription Factor Spx
Awad W, Al-Eryani Y, Ekström S, Logan DT, von Wachenfeldt C
Structure 27 (6) 923-936.e6 [2019-06-00; online 2019-06-00]
Targeted and Structural Proteomics [Service]
Rapid determination of quaternary protein structures in complex biological samples.
Hauri S, Khakzad H, Happonen L, ..., Malmström J, Malmström L
pii: 10.1038/s41467-018-07986-1 pmc: PMC6331586
Nat Commun 10 (1) 192 [2019-01-14; online 2019-01-14]
Targeted and Structural Proteomics [Technology development]

Year 2018

Structural basis for endotoxin neutralisation and anti-inflammatory activity of thrombin-derived C-terminal peptides.
Saravanan R, Holdbrook DA, Petrlova J, ..., Malmsten M, Schmidtchen A
pii: 10.1038/s41467-018-05242-0 pmc: PMC6050251
Nat Commun 9 (1) 2762 [2018-07-17; online 2018-07-17]
Targeted and Structural Proteomics [Service]
BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma.
Sime W, Niu Q, Abassi Y, ..., Fu H, Massoumi R
pii: 10.1038/s41419-018-0500-6 pmc: PMC5913307
Cell Death Dis 9 (5) 458 [2018-05-01; online 2018-05-01]
Targeted and Structural Proteomics [Service]
Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells
Guzzi N, Cieśla M, Ngoc PCT, ..., Hsieh AC, Bellodi C
Cell 173 (5) 1204-1216.e26 [2018-05-00; online 2018-05-00]
Targeted and Structural Proteomics [Service]
Allele-selective RUNX1 binding regulates P1 blood group status by transcriptional control of A4GALT.
Westman JS, Stenfelt L, Vidovic K, ..., Kjellström S, Olsson ML
pii: blood-2017-08-803080
Blood 131 (14) 1611-1616 [2018-04-05; online 2018-02-08]
Targeted and Structural Proteomics [Service]
Proteomic analyses identify prognostic biomarkers for pancreatic ductal adenocarcinoma.
Hu D, Ansari D, Pawłowski K, ..., Marko-Varga G, Andersson R
pii: 23929 pmc: PMC5839402
Oncotarget 9 (11) 9789-9807 [2018-02-09; online 2018-01-03]
Targeted and Structural Proteomics [Service]

Year 2017

Proteolytic signatures define unique thrombin-derived peptides present in human wound fluid in vivo.
Saravanan R, Adav SS, Choong YK, ..., Sze SK, Schmidtchen A
pii: 10.1038/s41598-017-13197-3 pmc: PMC5640616
Sci Rep 7 (1) 13136 [2017-10-13; online 2017-10-13]
Targeted and Structural Proteomics [Service]
Quantitative proteomic characterization of lung-MSC and bone marrow-MSC using DIA-mass spectrometry.
Rolandsson Enes S, Åhrman E, Palani A, ..., Malmström J, Westergren-Thorsson G
pii: 10.1038/s41598-017-09127-y pmc: PMC5570998
Sci Rep 7 (1) 9316 [2017-08-24; online 2017-08-24]
Targeted and Structural Proteomics [Service]
Epitope mapping of a new anti-Tn antibody detecting gastric cancer cells.
Persson N, Stuhr-Hansen N, Risinger C, ..., Jansson B, Blixt O
pii: 3611453
Glycobiology 27 (7) 635-645 [2017-07-01; online 2017-04-19]
Targeted and Structural Proteomics [Service]
Correlation of histopathologic characteristics to protein expression and function in malignant melanoma.
Welinder C, Pawłowski K, Szasz AM, ..., Wieslander E, Marko-Varga G
pii: PONE-D-16-43238 pmc: PMC5405986
PLoS ONE 12 (4) e0176167 [2017-04-26; online 2017-04-26]
Targeted and Structural Proteomics [Service]

Year 2016

Exploring structure and interactions of the bacterial adaptor protein YjbH by crosslinking mass spectrometry.
Al-Eryani Y, Ib Rasmussen M, Kjellström S, ..., Emanuelsson C, von Wachenfeldt C
Proteins 84 (9) 1234-1245 [2016-09-00; online 2016-06-15]
Targeted and Structural Proteomics [Service]
Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan-Dependent Endocytosis.
Menard JA, Christianson HC, Kucharzewska P, ..., Johansson MC, Belting M
pii: 0008-5472.CAN-15-2831
Cancer Res. 76 (16) 4828-4840 [2016-08-15; online 2016-05-19]
Targeted and Structural Proteomics [Service]
Intra-tumour IgA1 is common in cancer and is correlated with poor prognosis in bladder cancer.
Welinder C, Jirström K, Lehn S, ..., Danielsson L, Jansson B
pii: S2405-8440(16)30369-3 pii: e00143 pmc: PMC4992093
Heliyon 2 (8) e00143 [2016-08-00; online 2016-08-16]
Targeted and Structural Proteomics [Service]
Multiplexed MALDI-MS arrays for screening of MIP solid phase extraction materials
Jagadeesan KK, Wierzbicka C, Laurell T, ..., Shinde S, Ekström S
Journal of Chromatography B 1021 (-) 213-220 [2016-05-00; online 2016-05-00]
Targeted and Structural Proteomics [Service]
Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells.
Bourseau-Guilmain E, Menard JA, Lindqvist E, ..., Welinder C, Belting M
pii: ncomms11371 pmc: PMC4842985
Nat Commun 7 (-) 11371 [2016-04-20; online 2016-04-20]
Targeted and Structural Proteomics [Service]