Proteogenomics

SciLifeLab Infrastructure Unit Since 2017.

Started: 2017

Ended: Current

60 publications

Year 2021

Mechanism of membrane-tethered mitochondrial protein synthesis
Itoh Y, Andréll J, Choi A, ..., Battersby BJ, Amunts A
Science 371 (6531) 846-849 [2021-02-19; online 2021-02-18]
Cryo-EM [Service] Proteogenomics [Service]
ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria.
Mühleip A, Kock Flygaard R, Ovciarikova J, ..., Sheiner L, Amunts A
pii: 10.1038/s41467-020-20381-z
Nat Commun 12 (1) 120 [2021-01-05; online 2021-01-05]
Cryo-EM [Service] Proteogenomics [Service]

Year 2020

Type III ATP synthase is a symmetry-deviated dimer that induces membrane curvature through tetramerization.
Flygaard RK, Mühleip A, Tobiasson V, Amunts A
pii: 10.1038/s41467-020-18993-6
Nat Commun 11 (1) 5342 [2020-10-22; online 2020-10-22]
Cryo-EM [Service] Proteogenomics [Service]
Structural basis of mitochondrial translation
Aibara S, Singh V, Modelska A, Amunts A
Elife 9 (-) 1-17 [2020-08-19; online 2020-08-19]
Cryo-EM [Service] Proteogenomics [Service]

Year 2019

A Mitochondrial LYR Protein Is Required for Complex I Assembly.
Ivanova A, Gill-Hille M, Huang S, ..., Whelan J, Murcha MW
pii: pp.19.00822 pmc: PMC6878026
Plant Physiol. 181 (4) 1632-1650 [2019-12-00; online 2019-10-10]
Proteogenomics [Collaborative]
MYCN-enhanced Oxidative and Glycolytic Metabolism Reveals Vulnerabilities for Targeting Neuroblastoma.
Oliynyk G, Ruiz-Pérez MV, Sainero-Alcolado L, ..., Lehtiö J, Arsenian-Henriksson M
pii: S2589-0042(19)30399-2 pmc: PMC6889365
iScience 21 (-) 188-204 [2019-11-22; online 2019-10-11]
Bioinformatics Compute and Storage [Service] Proteogenomics [Collaborative]
Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2
Testini C, Smith RO, Jin Y, ..., Hellström M, Claesson‐Welsh L
EMBO rep 20 (11) - [2019-11-05; online 2019-09-23]
Proteogenomics [Service]
Molecular Basis and Ecological Relevance of Caulobacter Cell Filamentation in Freshwater Habitats
Heinrich K, Leslie DJ, Morlock M, Bertilsson S, Jonas K
MBio 10 (4) - [2019-08-20; online 2019-08-20]
Proteogenomics [Service]
The viral protein corona directs viral pathogenesis and amyloid aggregation.
Ezzat K, Pernemalm M, Pålsson S, ..., Spetz AL, El Andaloussi S
pii: 10.1038/s41467-019-10192-2 pmc: PMC6536551
Nat Commun 10 (1) 2331 [2019-05-27; online 2019-05-27]
Bioinformatics Compute and Storage [Service] Proteogenomics [Technology development]

Year 2018

Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens
Srinivas V, Lebrette H, Lundin D, ..., Sjöberg BM, Högbom M
Nature 563 (7731) 416-420 [2018-11-00; online 2018-10-31]
Proteogenomics [Collaborative]
MYCN-amplified neuroblastoma maintains an aggressive and undifferentiated phenotype by deregulation of estrogen and NGF signaling
Dzieran J, Rodriguez Garcia A, Westermark UK, ..., Lehtiö J, Arsenian-Henriksson M
Proc Natl Acad Sci USA 115 (6) E1229-E1238 [2018-02-06; online 2018-01-26]
Proteogenomics [Collaborative]

Year 2017

Normalization of mass spectrometry data (NOMAD).
Murie C, Sandri B, Sandberg AS, ..., Wendt C, Larsson O
pii: S2212-4926(17)30174-4
Adv Biol Regul - (-) - [2017-11-20; online 2017-11-20]
Clinical Proteomics Mass spectrometry [Service] Proteogenomics [Service]
Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.
Egaña I, Kaito H, Nitzsche A, ..., Hellström M, German Mouse Clinic Consortium
pii: 10.1038/s41598-017-14894-9 pmc: PMC5684320
Sci Rep 7 (1) 15453 [2017-11-13; online 2017-11-13]
Clinical Proteomics Mass spectrometry [Service] Proteogenomics [Collaborative]

Year 2016