Cell Profiling

SciLifeLab Infrastructure Unit Since 2013.

Started: 2013

Ended: Current

63 publications

Year 2021

Subcellular proteomics
Christopher JA, Stadler C, Martin CE, ..., Emili A, Lilley KS
Nat Rev Methods Primers 1 (1) - [2021-12-00; online 2021-04-29]
Cell Profiling
Spatiotemporal dissection of the cell cycle with single-cell proteogenomics
Mahdessian D, Cesnik AJ, Gnann C, ..., Sullivan DP, Lundberg E
Nature 590 (7847) 649-654 [2021-02-25; online 2021-02-24]
Cell Profiling Eukaryotic Single Cell Genomics (ESCG)

Year 2020

Year 2019

Immune-informed mucin hydrogels evade fibrotic foreign body response in vivo
Yan H, Seignez C, Hjorth M, ..., Phillipson M, Crouzier T
- - (-) - [2019-02-19; online 2019-02-19]
Cell Profiling [Service]
Spatiotemporal dissection of the cell cycle regulated human proteome
Mahdessian D, Sullivan D, Danielsson F, ..., Lindskog C, Lundberg E
- - (-) - [2019-02-07; online 2019-02-07]
Bioinformatics Compute and Storage [Service] Cell Profiling [Collaborative]

Year 2018

Year 2017

Year 2016

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.
Scharaw S, Iskar M, Ori A, ..., Bork P, Pepperkok R
pii: jcb.201601090 pmc: PMC5119934
J. Cell Biol. 215 (4) 543-558 [2016-11-21; online 2016-11-08]
Cell Profiling [Collaborative]
A proposal for validation of antibodies.
Uhlen M, Bandrowski A, Carr S, ..., Snyder M, Yamamoto T
pii: nmeth.3995
Nat. Methods 13 (10) 823-827 [2016-10-00; online 2016-09-07]
Cell Profiling [Collaborative]

Year 2015

The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation.
Gustafsson Sheppard N, Jarl L, Mahadessian D, ..., Jain M, Nilsson R
pii: srep15029 pmc: PMC4602236
Sci Rep 5 (-) 15029 [2015-10-13; online 2015-10-13]
Cell Profiling
Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project.
Horvatovich P, Lundberg EK, Chen YJ, ..., Paik YK, Hancock WS
J. Proteome Res. 14 (9) 3415-3431 [2015-09-04; online 2015-06-16]
Cell Profiling

Year 2014

Immunoproteomics using polyclonal antibodies and stable isotope-labeled affinity-purified recombinant proteins.
Edfors F, Boström T, Forsström B, ..., Mann M, Uhlen M
pii: M113.034140 pmc: PMC4047479
Mol. Cell Proteomics 13 (6) 1611-1624 [2014-06-00; online 2014-04-12]
Cell Profiling
A chromosome-centric analysis of antibodies directed toward the human proteome using Antibodypedia.
Alm T, von Feilitzen K, Lundberg E, Sivertsson Å, Uhlén M
J. Proteome Res. 13 (3) 1669-1676 [2014-03-07; online 2014-02-19]
Cell Profiling
Antibody performance in western blot applications is context-dependent.
Algenäs C, Agaton C, Fagerberg L, ..., Ottosson Takanen J, Hober S
Biotechnol J 9 (3) 435-445 [2014-03-00; online 2014-01-10]
Cell Profiling Tissue Profiling

Year 2013

Initial quantitative proteomic map of 28 mouse tissues using the SILAC mouse.
Geiger T, Velic A, Macek B, ..., Cox J, Mann M
pii: M112.024919 pmc: PMC3675825
Mol. Cell Proteomics 12 (6) 1709-1722 [2013-06-00; online 2013-02-26]
Cell Profiling Tissue Profiling
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells.
Stadler C, Rexhepaj E, Singan VR, ..., Simpson JC, Lundberg E
pii: nmeth.2377
Nat. Methods 10 (4) 315-323 [2013-04-00; online 2013-02-26]
Cell Profiling

Year 2012

Automated analysis and reannotation of subcellular locations in confocal images from the Human Protein Atlas.
Li J, Newberg JY, Uhlén M, Lundberg E, Murphy RF
pii: PONE-D-12-11801 pmc: PMC3511558
PLoS ONE 7 (11) e50514 [2012-11-30; online 2012-11-30]
Cell Profiling
A tool to facilitate clinical biomarker studies--a tissue dictionary based on the Human Protein Atlas.
Kampf C, Bergman J, Oksvold P, ..., Uhlén M, Ponten F
pii: 1741-7015-10-103 pmc: PMC3523031
BMC Med 10 (-) 103 [2012-09-12; online 2012-09-12]
Cell Profiling Tissue Profiling
Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy.
Stadler C, Hjelmare M, Neumann B, ..., Uhlén M, Lundberg E
pii: S1874-3919(12)00070-X
J Proteomics 75 (7) 2236-2251 [2012-04-03; online 2012-03-01]
Cell Profiling
Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens.
Dengjel J, Høyer-Hansen M, Nielsen MO, ..., Jäättelä M, Andersen JS
pii: M111.014035 pmc: PMC3316729
Mol. Cell Proteomics 11 (3) M111.014035 [2012-03-00; online 2012-02-09]
Cell Profiling
Antibody-based protein profiling of the human chromosome 21.
Uhlén M, Oksvold P, Älgenäs C, ..., Kondo T, Sivertsson Å
pii: M111.013458 pmc: PMC3316724
Mol. Cell Proteomics 11 (3) M111.013458 [2012-03-00; online 2011-11-02]
Cell Profiling Tissue Profiling
Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.
Larance M, Kirkwood KJ, Xirodimas DP, ..., Uhlen M, Lamond AI
pii: M111.014407 pmc: PMC3316733
Mol. Cell Proteomics 11 (3) M111.014407 [2012-03-00; online 2011-11-01]
Cell Profiling

Year 2011

Mapping the subcellular protein distribution in three human cell lines.
Fagerberg L, Stadler C, Skogs M, ..., Uhlén M, Lundberg E
J. Proteome Res. 10 (8) 3766-3777 [2011-08-05; online 2011-06-17]
Cell Profiling
SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas.
Magnusson K, de Wit M, Brennan DJ, ..., Jirström K, Pontén F
pii: 00000478-201107000-00001
Am. J. Surg. Pathol. 35 (7) 937-948 [2011-07-00; online 2011-06-17]
Cell Profiling Tissue Profiling
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
Jakobsen L, Vanselow K, Skogs M, ..., Hyman AA, Andersen JS
pii: emboj201163 pmc: PMC3102290
EMBO J. 30 (8) 1520-1535 [2011-04-20; online 2011-03-15]
Cell Profiling

Year 2010

Towards a knowledge-based Human Protein Atlas.
Uhlen M, Oksvold P, Fagerberg L, ..., Björling L, Ponten F
pii: nbt1210-1248
Nat. Biotechnol. 28 (12) 1248-1250 [2010-12-00; online 2010-12-09]
Autoimmunity and Serology Profiling [Technology development] Cell Profiling
Creation of an antibody-based subcellular protein atlas.
Lundberg E, Uhlén M
Proteomics 10 (22) 3984-3996 [2010-11-00; online 2010-07-22]
Cell Profiling
A single fixation protocol for proteome-wide immunofluorescence localization studies.
Stadler C, Skogs M, Brismar H, Uhlén M, Lundberg E
pii: S1874-3919(09)00310-8
J Proteomics 73 (6) 1067-1078 [2010-04-18; online 2009-11-10]
Cell Profiling