Advanced Light Microscopy (ALM)

Primary cell wall inspired micro containers as a step towards a synthetic plant cell

Paulraj T, Wennmalm S, Wieland DCF, ..., Cárdenas M, Svagan AJ

Nat Commun 11 (1) - [2020-12-00; online 2020-02-19]

Extracellular vesicles from mast cells induce mesenchymal transition in airway epithelial cells

Yin Y, Shelke GV, Lässer C, Brismar H, Lötvall J

Respir. Res. 21 (1) - [2020-12-00; online 2020-05-01]

Ouabain Modulates the Functional Interaction Between Na,K-ATPase and NMDA Receptor

Akkuratov EE, Westin L, Vazquez-Juarez E, ..., Brismar H, Aperia A

Mol Neurobiol - (-) - [2020-07-10; online 2020-07-10]

Advanced Light Microscopy (ALM) [Technology development]

GPSeq reveals the radial organization of chromatin in the cell nucleus

Girelli G, Custodio J, Kallas T, ..., Crosetto N, Bienko M

Nat Biotechnol - (-) - [2020-05-25; online 2020-05-25]

A molecular mechanism explaining albuminuria in kidney disease

Butt L, Unnersjö-Jess D, Höhne M, ..., Schermer B, Benzing T

Nat Metab 2 (5) 461-474 [2020-05-00; online 2020-05-11]

Interactions of the Lysosomotropic Detergent O-Methyl-Serine Dodecylamide Hydrochloride (MSDH) with Lipid Bilayer Membranes—Implications for Cell Toxicity

Villamil Giraldo AM, Eriksson I, Wennmalm S, ..., Ederth T, Öllinger K

Int J Mol Sci 21 (9) 3136 [2020-04-29; online 2020-04-29]

Year 2019

Coro2b, a podocyte protein downregulated in human diabetic nephropathy, is involved in the development of protamine sulphate-induced foot process effacement

Schwarz A, Möller-Hackbarth K, Ebarasi L, ..., Lal M, Patrakka J

Sci Rep 9 (1) - [2019-12-00; online 2019-06-20]

Breast cancer quantitative proteome and proteogenomic landscape

Johansson HJ, None , Socciarelli F, ..., Børresen-Dale AL, Lehtiö J

Nat Commun 10 (1) - [2019-12-00; online 2019-04-08]

Advanced Light Microscopy (ALM) [Service] Bioinformatics Compute and Storage [Service] Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Proteogenomics [Technology development]

Endocytic pathway of vascular cell adhesion molecule 1 in human umbilical vein endothelial cell identified in vitro by using functionalized nontoxic fluorescent quantum dots

Fu Y, Jussi J, Wang Q, ..., Yang X, Chen Y

Sensors and Actuators B: Chemical 297 (-) 126702 [2019-10-00; online 2019-10-00]

Joint Image Deconvolution and Separation Using Mixed Dictionaries

Siadat M, Aghazadeh N, Akbarifard F, Brismar H, Oktem O

IEEE Trans. on Image Process. 28 (8) 3936-3945 [2019-08-00; online 2019-08-00]

Advanced Light Microscopy (ALM) [Technology development]

Post‐metaphase correction of aberrant kinetochore‐microtubule attachments in mammalian eggs

Kouznetsova A, Kitajima TS, Brismar H, Höög C

EMBO rep - (-) - [2019-07-10; online 2019-07-10]

Correlative STED super-resolution light and electron microscopy on resin sections

Wurm CA, Schwarz H, Jans DC, ..., Humbel B, Jakobs S

J. Phys. D: Appl. Phys. - (-) - [2019-06-19; online 2019-06-19]

Advanced Light Microscopy (ALM) [Technology development]

Ouabain-regulated phosphoproteome reveals molecular mechanisms for Na+, K+–ATPase control of cell adhesion, proliferation, and survival

Panizza E, Zhang L, Fontana JM, ..., Lehtiö J, Aperia A

The FASEB Journal - (-) fj.201900445R [2019-06-14; online 2019-06-14]

Advanced Light Microscopy (ALM) [Collaborative] Bioinformatics Compute and Storage [Service] Proteogenomics [Technology development]

Prompt apoptotic response to high glucose in SGLT-expressing renal cells

Nilsson LM, Zhang L, Bondar A, ..., Scott L, Aperia A

American Journal of Physiology-Renal Physiology 316 (5) F1078-F1089 [2019-05-01; online 2019-05-01]

Advanced Light Microscopy (ALM) [Service] Bioinformatics Compute and Storage [Service]

Mic60 exhibits a coordinated clustered distribution along and across yeast and mammalian mitochondria

Stoldt S, Stephan T, Jans DC, ..., Hell SW, Jakobs S

Proc Natl Acad Sci USA - (-) 201820364 [2019-04-26; online 2019-04-26]

Spontaneous calcium activity in metanephric mesenchymal cells regulates branching morphogenesis in the embryonic kidney

Fontana JM, Khodus GR, Unnersjö-Jess D, ..., Aperia A, Brismar H

The FASEB Journal 33 (3) 4089-4096 [2019-03-00; online 2019-03-00]

Intrinsic blinking characteristics of single colloidal CdSe-CdS/ZnS core-multishell quantum dots

Fu Y, Jussi J, Elmlund L, ..., Wang Q, Brismar H

Phys. Rev. B 99 (3) - [2019-01-02; online 2019-01-02]

Year 2018

Porous Cellulose Nanofiber-Based Microcapsules for Biomolecular Sensing

Paulraj T, Wennmalm S, Riazanova AV, ..., Crespo GA, Svagan AJ

ACS Appl. Mater. Interfaces 10 (48) 41146-41154 [2018-12-05; online 2018-11-09]

Extracellular nanovesicles released from the commensal yeast Malassezia sympodialis are enriched in allergens and interact with cells in human skin

Johansson HJ, Vallhov H, Holm T, ..., Lehtiö J, Scheynius A

Sci Rep 8 (1) - [2018-12-00; online 2018-06-15]

Advanced Light Microscopy (ALM) [Collaborative] Bioinformatics Compute and Storage [Service] Cryo-EM [Service] Proteogenomics [Collaborative]

An orthotopic glioblastoma animal model suitable for high-throughput screenings

Pudelko L, Edwards S, Balan M, ..., Helleday T, Bräutigam L

Neuro Oncol 20 (11) 1475-1484 [2018-10-09; online 2018-05-10]

A Protein-Based Encapsulation System with Calcium-Controlled Cargo Loading and Detachment

Lizatović R, Assent M, Barendregt A, ..., Wennmalm S, André I

Angew. Chem. Int. Ed. 57 (35) 11334-11338 [2018-08-27; online 2018-07-30]

Regulation of Neuronal Na,K-ATPase by Extracellular Scaffolding Proteins

Liebmann T, Fritz N, Kruusmägi M, ..., Aperia A, Brismar H

Int J Mol Sci 19 (8) 2214 [2018-07-29; online 2018-07-29]

Advanced Light Microscopy (ALM) [Service] Bioinformatics Compute and Storage [Service]

OLMα2 Cells Bidirectionally Modulate Learning

Siwani S, França ASC, Mikulovic S, ..., Tort ABL, Kullander K

Neuron 99 (2) 404-412.e3 [2018-07-00; online 2018-07-00]

Advanced Light Microscopy (ALM) [Collaborative] Bioinformatics Compute and Storage [Service]

Stabilized Cyclic Peptides as Scavengers of Autoantibodies: Neutralization of Anticitrullinated Protein/Peptide Antibodies in Rheumatoid Arthritis

Gunasekera S, Fernandes-Cerqueira C, Wennmalm S, ..., Jakobsson PJ, Göransson U

ACS Chem. Biol. 13 (6) 1525-1535 [2018-06-15; online 2018-04-09]

Advanced Light Microscopy (ALM) [Collaborative] Bioinformatics Compute and Storage [Service] Swedish NMR Centre (SNC) [Service]

Neuronal Aβ42 is enriched in small vesicles at the presynaptic side of synapses

Yu Y, Jans DC, Winblad B, Tjernberg LO, Schedin-Weiss S

Life Sci. Alliance 1 (3) e201800028 [2018-06-00; online 2018-06-14]

Potentials and pitfalls of inverse fluorescence correlation spectroscopy

Wennmalm S

Methods 140-141 (-) 23-31 [2018-05-00; online 2018-05-00]

Advanced Light Microscopy (ALM) [Technology development]

Quantification of endogenous and exogenous protein expressions of Na,K-ATPase with super-resolution PALM/STORM imaging

Bernhem K, Blom H, Brismar H

Dryad

PLoS ONE 13 (4) e0195825 [2018-04-25; online 2018-04-25]

Advanced Light Microscopy (ALM) [Technology development] Bioinformatics Compute and Storage [Service]

Experimental validation of predicted cancer genes using FRET

Guala D, Bernhem K, Blal HA, ..., Brismar H, Sonnhammer ELL

Methods Appl. Fluoresc. 6 (3) 035007 [2018-04-25; online 2018-04-25]

Advanced Light Microscopy (ALM) [Collaborative] Bioinformatics Compute and Storage [Service]

Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions

Spiess M, Hernandez-Varas P, Oddone A, ..., Lakadamyali M, Strömblad S

J. Cell Biol. - (-) jcb.201707075 [2018-04-09; online 2018-04-09]

Confocal super-resolution imaging of the glomerular filtration barrier enabled by tissue expansion

Unnersjö-Jess D, Scott L, Sevilla SZ, ..., Blom H, Brismar H

Kidney International 93 (4) 1008-1013 [2018-04-00; online 2018-04-00]

Advanced Light Microscopy (ALM) [Technology development] Bioinformatics Compute and Storage [Service]

Sexual dimorphism in the width of the mouse synaptonemal complex

Agostinho A, Kouznetsova A, Hernández-Hernández A, ..., Brismar H, Höög C

J Cell Sci 131 (5) jcs212548 [2018-03-01; online 2018-02-02]

Educated natural killer cells show dynamic movement of the activating receptor NKp46 and confinement of the inhibitory receptor Ly49A

Staaf E, Hedde PN, Bagawath Singh S, ..., Gratton E, Johansson S

Sci. Signal. 11 (517) eaai9200 [2018-02-13; online 2018-02-13]

SMLocalizer, a GPU accelerated ImageJ plugin for single molecule localization microscopy

Bernhem K, Brismar H

Bioinformatics 34 (1) 137-138 [2018-01-01; online 2017-09-04]

Advanced Light Microscopy (ALM) [Technology development] Bioinformatics Compute and Storage [Service]

Year 2017

Glioblastoma and glioblastoma stem cells are dependent on functional MTH1

Pudelko L, Rouhi P, Sanjiv K, ..., Helleday T, Bräutigam L

Oncotarget 8 (49) - [2017-10-17; online 2017-07-20]

Multifocus structured illumination microscopy for fast volumetric super-resolution imaging

Abrahamsson S, Blom H, Agostinho A, ..., Heintzmann R, Brismar H

Biomed. Opt. Express 8 (9) 4135 [2017-09-01; online 2017-08-17]

Advanced Light Microscopy (ALM) [Technology development]

Cerium oxide nanoparticles inhibit differentiation of neural stem cells.

Gliga AR, Edoff K, Caputo F, ..., Ceccatelli S, Fadeel B

pmc

Sci Rep 7 (1) 9284 [2017-08-24; online 2017-08-24]

Advanced Light Microscopy (ALM) [Collaborative] Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Stimulated Emission Depletion Microscopy

Blom H, Widengren J

Chem. Rev. 117 (11) 7377-7427 [2017-06-14; online 2017-03-06]

Advanced Light Microscopy (ALM) [Technology development]

Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage

Kaucka M, Zikmund T, Tesarova M, ..., Fried K, Adameyko I

Elife 6 (-) - [2017-04-17; online 2017-04-17]

Measuring true localization accuracy in super resolution microscopy with DNA-origami nanostructures

Reuss M, Fördős F, Blom H, ..., Högberg B, Brismar H

New J. Phys. 19 (2) 025013 [2017-02-27; online 2017-02-27]

Advanced Light Microscopy (ALM) [Technology development]

Vimentin Levels and Serine 71 Phosphorylation in the Control of Cell-Matrix Adhesions, Migration Speed, and Shape of Transformed Human Fibroblasts

Terriac E, Coceano G, Mavajian Z, ..., Lautenschläger F, Gad A

Cells 6 (1) 2 [2017-01-22; online 2017-01-22]

Year 2016

Sodium pump organization in dendritic spines.

Blom H, Bernhem K, Brismar H

pmc

Neurophotonics 3 (4) 041803 [2016-10-00; online 2016-05-14]

Advanced Light Microscopy (ALM) [Technology development]

Profilin connects actin assembly with microtubule dynamics.

Nejedla M, Sadi S, Sulimenko V, ..., Aspenström P, Karlsson R

pmc

Mol. Biol. Cell 27 (15) 2381-2393 [2016-08-01; online 2016-06-17]

Analysis of neural crest-derived clones reveals novel aspects of facial development.

Kaucka M, Ivashkin E, Gyllborg D, ..., Hellander A, Adameyko I

pmc

Sci Adv 2 (8) e1600060 [2016-08-00; online 2016-08-03]

Prevention of apoptosis averts glomerular tubular disconnection and podocyte loss in proteinuric kidney disease.

Burlaka I, Nilsson LM, Scott L, ..., Brismar H, Aperia A

Kidney Int. 90 (1) 135-148 [2016-07-00; online 2016-05-25]

Super-resolution structured illumination fluorescence microscopy of the lateral wall of the cochlea: the Connexin26/30 proteins are separately expressed in man.

Liu W, Edin F, Blom H, ..., Laurell G, Rask-Andersen H

Cell Tissue Res. 365 (1) 13-27 [2016-07-00; online 2016-03-05]

High density of REC8 constrains sister chromatid axes and prevents illegitimate synaptonemal complex formation.

Agostinho A, Manneberg O, van Schendel R, ..., Brismar H, Höög C

pmc

EMBO Rep. 17 (6) 901-913 [2016-06-00; online 2016-05-14]

Microwell-Based Live Cell Imaging of NK Cell Dynamics to Assess Heterogeneity in Motility and Cytotoxic Response.

Vanherberghen B, Frisk T, Forslund E, ..., Guldevall K, Önfelt B

Methods Mol. Biol. 1441 (-) 87-106 [2016-05-15; online 2016-05-15]

Advanced Light Microscopy (ALM) [Technology development]

Microchip Screening Platform for Single Cell Assessment of NK Cell Cytotoxicity.

Guldevall K, Brandt L, Forslund E, ..., Uhlin M, Önfelt B

pmc

Front Immunol 7 (-) 119 [2016-04-05; online 2016-04-05]

Advanced Light Microscopy (ALM) [Technology development]

Na+-K+-ATPase, a new class of plasma membrane receptors.

Aperia A, Akkuratov EE, Fontana JM, Brismar H

Am. J. Physiol., Cell Physiol. 310 (7) C491-C495 [2016-04-01; online 2016-01-23]

Super-resolution microscopy reveals γ-secretase at both sides of the neuronal synapse.

Schedin-Weiss S, Caesar I, Winblad B, Blom H, Tjernberg LO

pmc

Acta Neuropathol Commun 4 (-) 29 [2016-03-31; online 2016-03-31]

Pseudomonas aeruginosa N-3-oxo-dodecanoyl-homoserine Lactone Elicits Changes in Cell Volume, Morphology, and AQP9 Characteristics in Macrophages

Holm A, Magnusson KE, Vikström E

Front. Cell. Infect. Microbiol. 6 (-) - [2016-03-24; online 2016-03-24]

Bioelectric and Morphological Response of Liquid-Covered Human Airway Epithelial Calu-3 Cell Monolayer to Periodic Deposition of Colloidal 3-Mercaptopropionic-Acid Coated CdSe-CdS/ZnS Core-Multishell Quantum Dots.

Turdalieva A, Solandt J, Shambetova N, ..., Zelenina M, Fu Y

pmc

PLoS ONE 11 (2) e0149915 [2016-02-25; online 2016-02-25]

Super-resolution stimulated emission depletion imaging of slit diaphragm proteins in optically cleared kidney tissue.

Unnersjö-Jess D, Scott L, Blom H, Brismar H

Kidney Int. 89 (1) 243-247 [2016-01-00; online 2015-10-08]

Advanced Light Microscopy (ALM) [Technology development]

Year 2015

BCG Skin Infection Triggers IL-1R-MyD88-Dependent Migration of EpCAMlow CD11bhigh Skin Dendritic cells to Draining Lymph Node During CD4+ T-Cell Priming.

Bollampalli VP, Harumi Yamashiro L, Feng X, ..., Nylén S, Rothfuchs AG

pmc

PLoS Pathog. 11 (10) e1005206 [2015-10-00; online 2015-10-06]

Pseudomonas aeruginosa lasI/rhlI quorum sensing genes promote phagocytosis and aquaporin 9 redistribution to the leading and trailing regions in macrophages.

Holm A, Karlsson T, Vikström E

pmc

Front Microbiol 6 (-) 915 [2015-09-03; online 2015-09-03]

Compaction of rolling circle amplification products increases signal integrity and signal-to-noise ratio.

Clausson C, Arngården L, Ishaq O, ..., Wählby C, Söderberg O

pmc

Sci Rep 5 (-) 12317 [2015-07-23; online 2015-07-23]

Advanced Light Microscopy (ALM) [Collaborative] BioImage Informatics [Technology development]

Dynamics of Cell Generation and Turnover in the Human Heart.

Bergmann O, Zdunek S, Felker A, ..., Druid H, Frisén J

Cell 161 (7) 1566-1575 [2015-06-18; online 2015-06-16]

Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery.

Mørch Ý, Hansen R, Berg S, ..., de Lange Davies C, Stenstad PM

Contrast Media Mol Imaging 10 (5) 356-366 [2015-04-30; online 2015-04-30]

SLC10A4 is a vesicular amine-associated transporter modulating dopamine homeostasis.

Larhammar M, Patra K, Blunder M, ..., Wallén-Mackenzie Å, Kullander K

Biol. Psychiatry 77 (6) 526-536 [2015-03-15; online 2014-09-02]

Year 2014

Glial origin of mesenchymal stem cells in a tooth model system.

Kaukua N, Shahidi MK, Konstantinidou C, ..., Fried K, Adameyko I

Nature 513 (7519) 551-554 [2014-09-25; online 2014-08-01]

Disassembly of the divisome in Escherichia coli: evidence that FtsZ dissociates before compartmentalization.

Söderström B, Skoog K, Blom H, ..., von Heijne G, Daley DO

pmc mid

Mol. Microbiol. 92 (1) 1-9 [2014-04-00; online 2014-02-11]

Nanoscopic spine localization of Norbin, an mGluR5 accessory protein.

Westin L, Reuss M, Lindskog M, Aperia A, Brismar H

pmc

BMC Neurosci 15 (-) 45 [2014-03-26; online 2014-03-26]

Advanced Light Microscopy (ALM) [Technology development]

Year 2013

Nanoscale elucidation of Na,K-ATPase isoforms in dendritic spines

Liebmann T, Blom H, Aperia A, Brismar H

Optical Nanoscopy Opt Nanoscopy 2 (1) 6 [2013-00-00; online 2013-00-00]

Advanced Light Microscopy (ALM) [Technology development]

Year 2012

The Pseudomonas aeruginosa N-acylhomoserine lactone quorum sensing molecules target IQGAP1 and modulate epithelial cell migration.

Karlsson T, Turkina MV, Yakymenko O, Magnusson K, Vikström E

pmc

PLoS Pathog. 8 (10) e1002953 [2012-10-11; online 2012-10-11]

Sequential closure of the cytoplasm and then the periplasm during cell division in Escherichia coli.

Skoog K, Söderström B, Widengren J, von Heijne G, Daley DO

pmc

J. Bacteriol. 194 (3) 584-586 [2012-02-00; online 2011-11-22]