{"entity": "journal", "iuid": "c7d339d71e874b9bb10a5dc961b94123", "timestamp": "2026-07-13T08:55:59.943Z", "links": {"self": {"href": "https://publications.scilifelab.se/journal/Langmuir.json"}, "display": {"href": "https://publications.scilifelab.se/journal/Langmuir"}}, "title": "Langmuir", "issn": "1520-5827", "issn-l": "0743-7463", "publications_count": 6, "publications": [{"entity": "publication", "iuid": "cc6f7e72892a4f618e0c7a1b7d271f07", "links": {"self": {"href": "https://publications.scilifelab.se/publication/cc6f7e72892a4f618e0c7a1b7d271f07.json"}, "display": {"href": "https://publications.scilifelab.se/publication/cc6f7e72892a4f618e0c7a1b7d271f07"}}, "title": "Water Film-Driven Brucite Nanosheet Growth and Stacking.", "authors": [{"family": "Luong", "given": "N Tan", "initials": "NT"}, {"family": "Boily", "given": "Jean-Fran\u00e7ois", "initials": "JF", "orcid": "0000-0003-4954-6461", "researcher": {"href": "https://publications.scilifelab.se/researcher/0a8cc96018014a97a0ab7e99b4fc0eb5.json"}}], "type": "journal article", "published": "2023-08-08", "journal": {"title": "Langmuir", "issn": "1520-5827", "volume": "39", "issue": "31", "pages": "11090-11098", "issn-l": "0743-7463"}, "abstract": "Thin water films that form by the adhesion and condensation of air moisture on minerals can initiate phase transformation reactions with broad implications in nature and technology. We here show important effects of water film coverages on reaction rates and products during the transformation of periclase (MgO) nanocubes to brucite [Mg(OH)2] nanosheets. Using vibrational spectroscopy, we found that the first minutes to hours of Mg(OH)2 growth followed first-order kinetics, with rates scaling with water loadings. Growth was tightly linked to periclase surface hydration and to the formation of a brucite precursor solid, akin to poorly stacked/dislocated nanosheets. These nanosheets were the predominant forms of Mg(OH)2 growth in the 2D-like hydration environments of sub-monolayer water films, which formed below \u223c50% relative humidity (RH). From molecular simulations, we infer that reactions may have been facilitated near surface defects where sub-monolayer films preferentially accumulated. In contrast, the 3D-like hydration environment of multilayered water films promoted brucite nanoparticle formation by enhancing Mg(OH)2 nanosheet growth and stacking rates and yields. From the structural similarity of periclase and brucite to other metal (hydr)oxide minerals, this concept of contrasting nanosheet growth should even be applicable for explaining water film-driven mineralogical transformations on other related nanominerals.", "doi": "10.1021/acs.langmuir.3c01411", "pmid": "37486722", "labels": {"Integrated Microscopy Technologies Ume\u00e5": "Service"}, "xrefs": [{"db": "pmc", "key": "PMC10413962"}], "notes": [], "created": "2023-11-28T12:27:13.206Z", "modified": "2023-11-28T12:27:13.214Z"}, {"entity": "publication", "iuid": "8225e98e6c16416bad28e5ef097f8407", "links": {"self": {"href": "https://publications.scilifelab.se/publication/8225e98e6c16416bad28e5ef097f8407.json"}, "display": {"href": "https://publications.scilifelab.se/publication/8225e98e6c16416bad28e5ef097f8407"}}, "title": "Intracrystalline Transport Barriers Affecting the Self-Diffusion of CH4 in Zeolites |Na12|-A and |Na12\u2013K|-A", "authors": [{"family": "Hedin", "given": "Niklas", "initials": "N", "orcid": "0000-0002-7284-2974", "researcher": {"href": "https://publications.scilifelab.se/researcher/36ec1b6fa2654626b17b88e7c9d18412.json"}}, {"family": "Rzepka", "given": "Przemyslaw", "initials": "P", "orcid": "0000-0003-3185-3535", "researcher": {"href": "https://publications.scilifelab.se/researcher/7c11e0ded4eb4ce189f907d4f554b580.json"}}, {"family": "Jasso-Salcedo", "given": "Alma Berenice", "initials": "AB"}, {"family": "Church", "given": "Tamara L", "initials": "TL", "orcid": "0000-0002-0494-9657", "researcher": {"href": "https://publications.scilifelab.se/researcher/72b6f8f1af2d402b904504fcc8ca0686.json"}}, {"family": "Bernin", "given": "Diana", "initials": "D", "orcid": "0000-0002-9611-2263", "researcher": {"href": "https://publications.scilifelab.se/researcher/7ad134b1d8ab41b8a8a3318801d92e10.json"}}], "type": "journal-article", "published": "2019-10-08", "journal": {"title": "Langmuir", "issn": "0743-7463", "volume": "35", "issue": "40", "pages": "12971-12978", "issn-l": null}, "abstract": "Carbon dioxide must be removed from biogas or natural gas to obtain compressed or liquefied methane, and adsorption-driven isolation of CO2 could be improved by developing new adsorbents. Zeolite adsorbents can select CO2 over CH4, and the adsorption of CH4 on zeolite |Na12-Kx|-A is significantly lower for samples with a high Kx+ content, i.e., x > 2. Nevertheless, we show, using 1H NMR experiments, that these zeolites adsorb CH4 after long equilibration times. Pulsed-field gradient NMR experiments indicated that in large crystals of zeolites |Na12-Kx|-A, the long-time diffusion coefficients of CHx4 did not vary with x, and the upper limit of the mean-square displacement was about 1.5 \u03bcm, irrespective of the diffusion time. Also for zeolite |Na12|-A samples of three different particle sizes (\u223c0.44, \u223c2.9, and \u223c10.6 \u03bcm), the upper limit of the mean-square displacement of CH4 was 1.5 \u03bcm and largely independent of the diffusion time. This similarity provided further evidence for an intracrystalline diffusion restriction for CH4 within the medium- and large-sized zeolite A crystals and possibly of clustering and close contact among the small zeolite A crystals. The upper limit of the long-time diffusion coefficient of adsorbed CH4 was (at 1 atm and 298 K) about 10-10 m2/s irrespective of the size of the zeolite particle or the studied content of K+ in zeolites |Na12-Kx|-A and |Nax12|-A. The T1 relaxation time for adsorbed CH4 on zeolites |Na12-Kx|-A with xx > 2 was smaller than for those with x < 2, indicating that the short-time diffusion of CH4 was hindered.", "doi": "10.1021/acs.langmuir.9b02574", "pmid": "31510744", "labels": {"Swedish NMR Centre": "Collaborative"}, "xrefs": [], "notes": [], "created": "2023-05-31T16:48:06.605Z", "modified": "2025-10-17T13:03:57.510Z"}, {"entity": "publication", "iuid": "436bb1985ced401fb83d2cb3f9b0b9af", "links": {"self": {"href": "https://publications.scilifelab.se/publication/436bb1985ced401fb83d2cb3f9b0b9af.json"}, "display": {"href": "https://publications.scilifelab.se/publication/436bb1985ced401fb83d2cb3f9b0b9af"}}, "title": "Dispersed Uniform Nanoparticles from a Macroscopic Organosilica Powder.", "authors": [{"family": "Church", "given": "Tamara L", "initials": "TL"}, {"family": "Bernin", "given": "Diana", "initials": "D", "orcid": "0000-0002-9611-2263", "researcher": {"href": "https://publications.scilifelab.se/researcher/7ad134b1d8ab41b8a8a3318801d92e10.json"}}, {"family": "Garcia-Bennett", "given": "Alfonso E", "initials": "AE"}, {"family": "Hedin", "given": "Niklas", "initials": "N", "orcid": "0000-0002-7284-2974", "researcher": {"href": "https://publications.scilifelab.se/researcher/36ec1b6fa2654626b17b88e7c9d18412.json"}}], "type": "journal article", "published": "2018-02-13", "journal": {"volume": "34", "issn": "1520-5827", "issue": "6", "pages": "2274-2281", "title": "Langmuir", "issn-l": "0743-7463"}, "abstract": "A colloidal dispersion of uniform organosilica nanoparticles could be produced via the disassembly of the non-surfactant-templated organosilica powder nanostructured folate material (NFM-1). This unusual reaction pathway was available because the folate and silica-containing moieties in NFM-1 are held together by noncovalent interactions. No precipitation was observed from the colloidal dispersion after a week, though particle growth occurred at a solvent-dependent rate that could be described by the Lifshitz-Slyozov-Wagner equation. An organosilica film that was prepared from the colloidal dispersion adsorbed folate-binding protein from solution but adsorbed ions from a phosphate-buffered saline solution to a larger degree. To our knowledge, this is the first instance of a colloidal dispersion of organosilica nanoparticles being derived from a macroscopic material rather than from molecular precursors.", "doi": "10.1021/acs.langmuir.7b03705", "pmid": "29400064", "labels": {"Swedish NMR Centre": "Collaborative"}, "xrefs": [], "notes": [], "created": "2018-10-31T13:04:38.141Z", "modified": "2025-10-17T13:03:58.936Z"}, {"entity": "publication", "iuid": "bb6d4614c26347a3bd247c38cd10c6a2", "links": {"self": {"href": "https://publications.scilifelab.se/publication/bb6d4614c26347a3bd247c38cd10c6a2.json"}, "display": {"href": "https://publications.scilifelab.se/publication/bb6d4614c26347a3bd247c38cd10c6a2"}}, "title": "Influence of Glycosylation on Interfacial Properties of Recombinant Mucins: Adsorption, Surface Forces, and Friction.", "authors": [{"family": "An", "given": "Junxue", "initials": "J"}, {"family": "Jin", "given": "Chunsheng", "initials": "C"}, {"family": "D\u0117dinait\u0117", "given": "Andra", "initials": "A"}, {"family": "Holgersson", "given": "Jan", "initials": "J"}, {"family": "Karlsson", "given": "Niclas G", "initials": "NG"}, {"family": "Claesson", "given": "Per M", "initials": "PM"}], "type": "journal article", "published": "2017-05-09", "journal": {"volume": "33", "issn": "1520-5827", "issue": "18", "pages": "4386-4395", "title": "Langmuir", "issn-l": "0743-7463"}, "abstract": "Interfacial properties of two brush-with-anchor mucins, C-P55 and C-PSLex, have been investigated at the aqueous solution/poly(methyl methacrylate) (PMMA) interface. Both are recombinant mucin-type fusion proteins, produced by fusing the glycosylated mucin part of P-selectin glycoprotein ligand-1 (PSLG-1) to the Fc part of a mouse immunoglobulin in two different cells. They are mainly expressed as dimers upon production. Analysis of the O-glycans shows that the C-PSLex mucin has the longer and more branched side chains, but C-P55 has slightly higher sialic acid content. The adsorption of the mucins to PMMA surfaces was studied by quartz crystal microbalance with dissipation. The sensed mass, including the adsorbed mucin and water trapped in the layer, was found to be similar for these two mucin layers. Atomic force microscopy with colloidal probe was employed to study surface and friction forces between mucin-coated PMMA surfaces. Purely repulsive forces of steric origin were observed between mucin layers on compression, whereas a small adhesion was detected between both mucin layers on decompression. This was attributed to chain entanglement. The friction force between C-PSLex-coated PMMA is lower than that between C-P55-coated PMMA at low loads, but vice versa at high loads. We discuss our results in terms of the differences in the glycosylation composition of these two mucins.", "doi": "10.1021/acs.langmuir.7b00030", "pmid": "28431467", "labels": {"Glycoproteomics and MS Proteomics": "Collaborative"}, "xrefs": [], "notes": [], "created": "2020-01-30T16:19:34.217Z", "modified": "2024-01-16T13:46:32.669Z"}, {"entity": "publication", "iuid": "07e0aad42700478fbf4496f8b2c0521b", "links": {"self": {"href": "https://publications.scilifelab.se/publication/07e0aad42700478fbf4496f8b2c0521b.json"}, "display": {"href": "https://publications.scilifelab.se/publication/07e0aad42700478fbf4496f8b2c0521b"}}, "title": "Spontaneous Vesiculation and pH-Induced Disassembly of a Lysosomotropic Detergent: Impacts on Lysosomotropism and Lysosomal Delivery.", "authors": [{"family": "Villamil Giraldo", "given": "Ana M", "initials": "AM"}, {"family": "Fyrner", "given": "Timmy", "initials": "T"}, {"family": "Wennmalm", "given": "Stefan", "initials": "S"}, {"family": "Parikh", "given": "Atul N", "initials": "AN"}, {"family": "\u00d6llinger", "given": "Karin", "initials": "K"}, {"family": "Ederth", "given": "Thomas", "initials": "T"}], "type": "journal article", "published": "2016-12-20", "journal": {"volume": "32", "issn": "1520-5827", "issue": "50", "pages": "13566-13575", "title": "Langmuir", "issn-l": "0743-7463"}, "abstract": "Lysosomotropic detergents (LDs) selectively rupture lysosomal membranes through mechanisms that have yet to be characterized. A consensus view, currently, holds that LDs, which are weakly basic, diffuse across cellular membranes as monomers in an uncharged state, and via protonation in the acidic lysosomal compartment, they become trapped, accumulate, and subsequently solubilize the membrane and induce lysosomal membrane permeabilization. Here we demonstrate that the lysosomotropic detergent O-methyl-serine dodecylamide hydrochloride (MSDH) spontaneously assembles into vesicles at, and above, cytosolic pH, and that the vesicles disassemble as the pH reaches 6.4 or lower. The aggregation commences at concentrations below the range of those used in cell studies. Assembly and disassembly of the vesicles was studied via dynamic light scattering, zeta potential measurements, cryo-TEM, and fluorescence correlation spectroscopy and was found to be reversible via control of the pH. Aggregation of MSDH into closed vesicles under cytosolic conditions is at variance with the commonly held view of LD behavior, and we propose that endocytotic pathways should be considered as possible routes of LD entry into lysosomes. We further demonstrate that MSDH vesicles can be loaded with fluorophores via a solution transition from low to high pH, for subsequent release when the pH is lowered again. The ability to encapsulate molecular cargo into MSDH vesicles together with its ability to disaggregate at low pH and to permeabilize the lysosomal membrane presents an intriguing possibility to use MSDH as a delivery system.", "doi": "10.1021/acs.langmuir.6b03458", "pmid": "27936755", "labels": {"Fluorescence Correlation Spectroscopy": "Collaborative", "Integrated Microscopy Technologies Stockholm": null}, "xrefs": [], "notes": [], "created": "2017-05-03T12:59:26.728Z", "modified": "2021-05-24T15:33:38.044Z"}, {"entity": "publication", "iuid": "a64d69ed23e54353ba1043ae21711cfb", "links": {"self": {"href": "https://publications.scilifelab.se/publication/a64d69ed23e54353ba1043ae21711cfb.json"}, "display": {"href": "https://publications.scilifelab.se/publication/a64d69ed23e54353ba1043ae21711cfb"}}, "title": "Removal of total organic carbon from sewage wastewater using poly(ethylenimine)-functionalized magnetic nanoparticles.", "authors": [{"family": "Lakshmanan", "given": "Ramnath", "initials": "R"}, {"family": "Sanchez-Dominguez", "given": "Margarita", "initials": "M"}, {"family": "Matutes-Aquino", "given": "Jose A", "initials": "JA"}, {"family": "Wennmalm", "given": "Stefan", "initials": "S"}, {"family": "Kuttuva Rajarao", "given": "Gunaratna", "initials": "G"}], "type": "journal article", "published": "2014-02-04", "journal": {"volume": "30", "issn": "1520-5827", "issue": "4", "pages": "1036-1044", "title": "Langmuir", "issn-l": "0743-7463"}, "abstract": "The increased levels of organic carbon in sewage wastewater during recent years impose a great challenge to the existing wastewater treatment process (WWTP). Technological innovations are therefore sought that can reduce the release of organic carbon into lakes and seas. In the present study, magnetic nanoparticles (NPs) were synthesized, functionalized with poly(ethylenimine) (PEI), and characterized using TEM (transmission electron microscopy), X-ray diffraction (XRD), FTIR (Fourier transform infrared spectroscopy), CCS (confocal correlation spectroscopy), SICS (scattering interference correlation spectroscopy), magnetism studies, and thermogravimetric analysis (TGA). The removal of total organic carbon (TOC) and other contaminants using PEI-coated magnetic nanoparticles (PEI-NPs) was tested in wastewater obtained from the Hammarby Sj\u00f6stadsverk sewage plant, Sweden. The synthesized NPs were about 12 nm in diameter and showed a homogeneous particle size distribution in dispersion by TEM and CCS analyses, respectively. The magnetization curve reveals superparamagnetic behavior, and the NPs do not reach saturation because of surface anisotropy effects. A 50% reduction in TOC was obtained in 60 min when using 20 mg/L PEI-NPs in 0.5 L of wastewater. Along with TOC, other contaminants such as turbidity (89%), color (86%), total nitrogen (24%), and microbial content (90%) were also removed without significant changes in the mineral ion composition of wastewater. We conclude that the application of PEI-NPs has the potential to reduce the processing time, complexity, sludge production, and use of additional chemicals in the WWTP.", "doi": "10.1021/la404076n", "pmid": "24428551", "labels": {"Fluorescence Correlation Spectroscopy": "Collaborative", "Integrated Microscopy Technologies Stockholm": null}, "xrefs": [], "notes": [], "created": "2017-05-04T14:56:12.722Z", "modified": "2021-05-24T15:33:38.311Z"}], "created": "2017-05-09T09:12:39.153Z", "modified": "2020-11-27T13:14:04.308Z"}