{"entity": "journal", "iuid": "694e0884e9ee4ba68e89971f8798bdde", "timestamp": "2026-07-22T17:49:01.191Z", "links": {"self": {"href": "https://publications.scilifelab.se/journal/J.%20Nat.%20Prod..json"}, "display": {"href": "https://publications.scilifelab.se/journal/J.%20Nat.%20Prod."}}, "title": "J. Nat. Prod.", "issn": "1520-6025", "issn-l": "0163-3864", "publications_count": 5, "publications": [{"entity": "publication", "iuid": "025e768a51504535a00b3757d24df6d1", "links": {"self": {"href": "https://publications.scilifelab.se/publication/025e768a51504535a00b3757d24df6d1.json"}, "display": {"href": "https://publications.scilifelab.se/publication/025e768a51504535a00b3757d24df6d1"}}, "title": "Prenylated Flavonoids from the Roots of Tephrosia rhodesica.", "authors": [{"family": "Atilaw", "given": "Yoseph", "initials": "Y"}, {"family": "Muiva-Mutisya", "given": "Lois", "initials": "L"}, {"family": "Bogaerts", "given": "Jonathan", "initials": "J"}, {"family": "Duffy", "given": "Sandra", "initials": "S"}, {"family": "Valkonen", "given": "Arto", "initials": "A", "orcid": "0000-0003-2806-3807", "researcher": {"href": "https://publications.scilifelab.se/researcher/ab27a4a2b3da4f85a4068024ae0bd4ca.json"}}, {"family": "Heydenreich", "given": "Matthias", "initials": "M"}, {"family": "Avery", "given": "Vicky M", "initials": "VM"}, {"family": "Rissanen", "given": "Kari", "initials": "K", "orcid": "0000-0002-7282-8419", "researcher": {"href": "https://publications.scilifelab.se/researcher/0fbf32c0cbe34b069a07be5e23a3e638.json"}}, {"family": "Erd\u00e9lyi", "given": "M\u00e1t\u00e9", "initials": "M", "orcid": "0000-0003-0359-5970", "researcher": {"href": "https://publications.scilifelab.se/researcher/f772b571449e417ca6fda2eee361a0c3.json"}}, {"family": "Yenesew", "given": "Abiy", "initials": "A"}], "type": "journal article", "published": "2020-08-28", "journal": {"title": "J. Nat. Prod.", "issn": "1520-6025", "volume": "83", "issue": "8", "pages": "2390-2398", "issn-l": "0163-3864"}, "abstract": "Five new compounds-rhodimer (1), rhodiflavan A (2), rhodiflavan B (3), rhodiflavan C (4), and rhodacarpin (5)-along with 16 known secondary metabolites, were isolated from the CH2Cl2-CH3OH (1:1) extract of the roots of Tephrosia rhodesica. They were identified by NMR spectroscopic, mass spectrometric, X-ray crystallographic, and ECD spectroscopic analyses. The crude extract and the isolated compounds 2-5, 9, 15, and 21 showed activity (100% at 10 \u03bcg and IC50 = 5-15 \u03bcM) against the chloroquine-sensitive (3D7) strain of Plasmodium falciparum.", "doi": "10.1021/acs.jnatprod.0c00245", "pmid": "32790306", "labels": {"Swedish NMR Centre": "Service"}, "xrefs": [{"db": "pmc", "key": "PMC7460544"}], "notes": [], "created": "2023-05-31T16:25:54.732Z", "modified": "2025-10-17T13:03:56.647Z"}, {"entity": "publication", "iuid": "7744ce583f08458c9b5c9c8dea19b02d", "links": {"self": {"href": "https://publications.scilifelab.se/publication/7744ce583f08458c9b5c9c8dea19b02d.json"}, "display": {"href": "https://publications.scilifelab.se/publication/7744ce583f08458c9b5c9c8dea19b02d"}}, "title": "Isoflavones and Rotenoids from the Leaves of Millettia oblata ssp. teitensis", "authors": [{"family": "Deyou", "given": "Tsegaye", "initials": "T"}, {"family": "Marco", "given": "Makungu", "initials": "M"}, {"family": "Heydenreich", "given": "Matthias", "initials": "M"}, {"family": "Pan", "given": "Fangfang", "initials": "F"}, {"family": "Gruhonjic", "given": "Amra", "initials": "A"}, {"family": "Fitzpatrick", "given": "Paul A", "initials": "PA"}, {"family": "Koch", "given": "Andreas", "initials": "A"}, {"family": "Derese", "given": "Solomon", "initials": "S"}, {"family": "Pelletier", "given": "Jerry", "initials": "J"}, {"family": "Rissanen", "given": "Kari", "initials": "K"}, {"family": "Yenesew", "given": "Abiy", "initials": "A"}, {"family": "Erd\u00e9lyi", "given": "M\u00e1t\u00e9", "initials": "M"}], "type": "journal-article", "published": "2017-07-28", "journal": {"volume": "80", "issn": "1520-6025", "issue": "7", "pages": "2060-2066", "title": "J. Nat. Prod.", "issn-l": "0163-3864"}, "abstract": null, "doi": "10.1021/acs.jnatprod.7b00255", "pmid": "28665590", "labels": {"Swedish NMR Centre": "Service"}, "xrefs": [], "notes": [], "created": "2017-11-03T11:01:03.744Z", "modified": "2025-10-17T13:03:59.666Z"}, {"entity": "publication", "iuid": "8a7781e0bd8f4bb08cfb479a681554c1", "links": {"self": {"href": "https://publications.scilifelab.se/publication/8a7781e0bd8f4bb08cfb479a681554c1.json"}, "display": {"href": "https://publications.scilifelab.se/publication/8a7781e0bd8f4bb08cfb479a681554c1"}}, "title": "Flavonoids fromErythrina schliebenii", "authors": [{"family": "Nyandoro", "given": "Stephen S", "initials": "SS"}, {"family": "Munissi", "given": "Joan J E", "initials": "JJE"}, {"family": "Kombo", "given": "Msim", "initials": "M"}, {"family": "Mgina", "given": "Clarence A", "initials": "CA"}, {"family": "Pan", "given": "Fangfang", "initials": "F"}, {"family": "Gruhonjic", "given": "Amra", "initials": "A"}, {"family": "Fitzpatrick", "given": "Paul", "initials": "P"}, {"family": "Lu", "given": "Yu", "initials": "Y"}, {"family": "Wang", "given": "Bin", "initials": "B"}, {"family": "Rissanen", "given": "Kari", "initials": "K"}, {"family": "Erd\u00e9lyi", "given": "M\u00e1t\u00e9", "initials": "M"}], "type": "journal-article", "published": "2017-02-24", "journal": {"volume": "80", "issn": "1520-6025", "issue": "2", "pages": "377-383", "title": "J. Nat. Prod.", "issn-l": "0163-3864"}, "abstract": null, "doi": "10.1021/acs.jnatprod.6b00839", "pmid": "28112509", "labels": {"Swedish NMR Centre": "Service"}, "xrefs": [], "notes": [], "created": "2017-11-03T16:46:06.058Z", "modified": "2025-10-17T13:03:59.973Z"}, {"entity": "publication", "iuid": "ecbb9eedad564312b53c2998afae42cf", "links": {"self": {"href": "https://publications.scilifelab.se/publication/ecbb9eedad564312b53c2998afae42cf.json"}, "display": {"href": "https://publications.scilifelab.se/publication/ecbb9eedad564312b53c2998afae42cf"}}, "title": "Polyoxygenated Cyclohexenes and Other Constituents of Cleistochlamys kirkii Leaves", "authors": [{"family": "Nyandoro", "given": "Stephen S", "initials": "SS"}, {"family": "Munissi", "given": "Joan J E", "initials": "JJE"}, {"family": "Gruhonjic", "given": "Amra", "initials": "A"}, {"family": "Duffy", "given": "Sandra", "initials": "S"}, {"family": "Pan", "given": "Fangfang", "initials": "F"}, {"family": "Puttreddy", "given": "Rakesh", "initials": "R"}, {"family": "Holleran", "given": "John P", "initials": "JP"}, {"family": "Fitzpatrick", "given": "Paul A", "initials": "PA"}, {"family": "Pelletier", "given": "Jerry", "initials": "J"}, {"family": "Avery", "given": "Vicky M", "initials": "VM"}, {"family": "Rissanen", "given": "Kari", "initials": "K"}, {"family": "Erd\u00e9lyi", "given": "M\u00e1t\u00e9", "initials": "M"}], "type": "journal-article", "published": "2017-01-27", "journal": {"volume": "80", "issn": "1520-6025", "issue": "1", "pages": "114-125", "title": "J. Nat. Prod.", "issn-l": "0163-3864"}, "abstract": null, "doi": "10.1021/acs.jnatprod.6b00759", "pmid": "28001067", "labels": {"Swedish NMR Centre": "Service"}, "xrefs": [], "notes": [], "created": "2017-11-03T16:46:07.686Z", "modified": "2025-10-17T13:04:00.082Z"}, {"entity": "publication", "iuid": "1cc7f80d232c4416930b28041df06ff9", "links": {"self": {"href": "https://publications.scilifelab.se/publication/1cc7f80d232c4416930b28041df06ff9.json"}, "display": {"href": "https://publications.scilifelab.se/publication/1cc7f80d232c4416930b28041df06ff9"}}, "title": "Naphthalene Derivatives from the Roots of Pentas parvifolia and Pentas bussei.", "authors": [{"family": "Abdissa", "given": "Negera", "initials": "N"}, {"family": "Pan", "given": "Fangfang", "initials": "F"}, {"family": "Gruhonjic", "given": "Amra", "initials": "A"}, {"family": "Gr\u00e4fenstein", "given": "J\u00fcrgen", "initials": "J"}, {"family": "Fitzpatrick", "given": "Paul A", "initials": "PA"}, {"family": "Landberg", "given": "G\u00f6ran", "initials": "G"}, {"family": "Rissanen", "given": "Kari", "initials": "K"}, {"family": "Yenesew", "given": "Abiy", "initials": "A"}, {"family": "Erd\u00e9lyi", "given": "M\u00e1t\u00e9", "initials": "M"}], "type": "journal article", "published": "2016-09-23", "journal": {"volume": "79", "issn": "1520-6025", "issue": "9", "pages": "2181-2187", "title": "J. Nat. Prod.", "issn-l": "0163-3864"}, "abstract": "The phytochemical investigation of the CH2Cl2/MeOH (1:1) extract of the roots of Pentas parvifolia led to the isolation of three new naphthalenes, parvinaphthols A (1), B (2), and C (3), two known anthraquinones, and five known naphthalene derivatives. Similar investigation of the roots of Pentas bussei afforded a new polycyclic naphthalene, busseihydroquinone E (4), a new 2,2'-binaphthralenyl-1,1'-dione, busseihydroquinone F (5), and five known naphthalenes. All purified metabolites were characterized by NMR and MS data analyses, whereas the absolute configurations of 3 and 4 were determined by single-crystal X-ray diffraction studies. The E-geometry of compound 5 was supported by DFT-based chemical shift calculations. Compounds 2-4 showed marginal cytotoxicity against the MDA-MB-231 human triple-negative breast cancer cell line with IC50 values ranging from 62.3 to 129.6 \u03bcM.", "doi": "10.1021/acs.jnatprod.6b00178", "pmid": "27518587", "labels": {"Swedish NMR Centre": "Service"}, "xrefs": [], "notes": [], "created": "2017-05-03T13:02:48.892Z", "modified": "2025-10-17T13:04:00.367Z"}], "created": "2017-05-09T09:12:45.353Z", "modified": "2020-11-27T13:14:04.344Z"}